51 research outputs found

    Поховання на човнах у давніх слов'ян

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    У статті розповідається про ранньослов’янський обряд поховання на човнах. Наводяться данні археологічних розкопок на території України, середньовічні письмові джерела, елементи фольклору, що свідчать про наявність такого обряду.В статье рассказывается о древнеславянском обряде захоронения на лодках. Приводятся данные археологических раскопок на территории Украины, средневековые письменные источники, элементы фольклора, свидетельствующие о наличии такого обряда.In the article is told about the ancient-Slavonic ceremony of burial place on boats. Data of archaeological excavations on territories of Ukraine, medieval writing sources

    Spinal cord injury without radiological abnormality (SCIWORA) in a young female and pharmacological treatment option: a case report with review of literature

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    Acute spinal cord injury strikes labour active young and middle-aged population, especially men, and consequently usually results in difficult neurological sequel. Also disables normal quality of life and everyday functioning in these patients despite many available supportive measures. Spinal cord injury without radiological abnormality (SCIWORA) presents a great diagnostic challenge because radiological and computed tomography pictures are without visible pathology which would explain the new onset of the neurological deficit. For the first time we report a true spinal cord injury without radiological abnormality in the X-ray, computed tomography and magnetic resonance imaging in a young female manifested with moderate neurological deficit after the traffic accident. Although SCIWORA is very rare in adults, high level of suspicion in emergency department is advisable as the timely applied neuroprotective measures can prevent the onset of the neurological deficit. It is important to emphasize that emergency magnetic resonance imaging application is the diagnostic key. Albeit, the SCIWORA neurologic deficit can show up with a delay of four days after the spinal cord injury in a patient with a normal physical and radiological examination. Treatment of these patients is another challenge for every physician. In fact pharmacological treatment options are still in the experimental research phase. We can conclude that currently the neuroprotective measures of the acute spinal cord injury patient started in the emergency department regardless the radiological test findings represent the right and successful key treatment.

    Role of echocardiography in stress cardiomyopathy diagnosis after tracheal extubation

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    Stress cardiomyopathy or Takotsubo cardiomyopathy is a new syndrome and still insufficiently recognized among emergency patients, hospitalized patients. Many different physical and emotional stressors are triggers, but individual susceptibility to Takotsubo cardiomyopathy can not be predicted. Takotsubo cardiomyopathy in surgical and critical care population is a huge diagnostic challenge. Apart that these patients are treated in stressful environment and conditions. Postoperatively due to change of consciousness and inability to speak we can not rely on verbal symptoms to make differential diagnosis. Although essential sometimes they can not be submitted to coronary angiography to exclude obstructive coronary disease due many risk factors. So, then we follow clinical course, electrocardiographic, radiologic and echocardiographic dynamic changes, laboratory findings and consiliar opinion to make diagnosis. We represent a case of Takotsubo cardiomyopathy in a 59-years old postmenopausal Caucasian woman after tracheal extubation. She was submitted to surgery of intraabdominal collection evacuation in short general endotracheal anesthesia

    Value of Head CT Scan in the Emergency Department in Patients with Vertigo without Focal Neurological Abnormalities

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    BACKGROUND: Vertigo is a common symptom and reason for admission to the emergency department (ED). AIM: This research aimed to determine the incidence of clinically significant findings on computed tomography (CT) in patients with vertigo without focal neurological abnormalities in the ED. MATERIAL AND METHODS: The results of the native CT scans in the ED were retrospectively analysed. Exclusion criteria included: focal neurological abnormalities, underlying malignancy, brain metastasis, previous brain operation, headache, fever, nausea, vomiting, head trauma, coagulopathy. As a clinically significant finding, we took into an account tumour, haemorrhage and acute ischemic lesion. 72 patients fulfilled the set criteria, present vertigo, without focal neurological abnormalities. Out of 72 patients with a median age of 62 (23-87) years old, 54% of the patients were female, and 46% were male. RESULTS: Normal CT findings were found in 44 patients (61.1%), 28 patients (38.9%) had pathological findings, out of that number 23 (31.9%) findings were clinically irrelevant and 5 (6.9%) were clinically significant. Out of the 5 clinically significant findings, tumour process was found in 3 (4.2%) patients, haemorrhage was found in 1 (1.4%) patient, and the ischemic lesion was found in 1 (1.4%) patient. Additional evaluation of five clinically significant findings showed a change of initial diagnosis in one case, but the significance of the finding remained the same. CONCLUSION: Our study demonstrates a low diagnostic yield of head CT examination with 6.9% of clinically significant findings in patients with vertigo without focal neurological abnormalities

    Can a presepsin (SCD14-ST) obtained from tracheal aspirate be a biomarker for early-onset neonatal sepsis

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    © 2020, University of Kragujevac, Faculty of Science. All rights reserved. In absence of clear clinical signs and clear definition, neonatal sepsis is still one of the major cause of morbidity and mortality. Most researchs in past time was directional on finding new biomarkers with greater sensitivity and specific-ity in detection of neonatal sepsis. The aim of our study was to investigate if presepsin obtained from tracheal asprate in intubated newborns, can be a novel biomarker of systemic bacterial infection. Our ‘’case control’’ study included 60 newborns, 11 with suspected neonatal sepsis. Tracheal aspirate for examination was taken in the usual toilets, in asep-tic conditions, by lavage with 2 ml of 0.9% NaCl in Mucus suction set. In the same day were mesured presepsin (blood), CRP, PCT, leukocytes and neutrophyls, as well as blood cul-ture. Our research showed higher levels for PCT and prese-psin (blood) in septic newborns, as well as in newborns with clinical signs of SIRS. Presepsin obtained from a tracheal aspirate had high score for septic newborns. As the coefficients of simple linear correlation showed, there was quantitative agreement between presepsin (blood) with presepsin (trache-al aspirate)-increase in the value of one leads to an increase in other. In conjunction with an already validated markers of infection, presepsin obtained from tracheal aspirate cam be turned on in diagnostic procedures

    Effects of Si on the expression of miRNA398 and miRNA408 and its target gene, superoxide dismutase (CuSOD) in Fe deficient cucumber plants

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    Silicon (Si) is a beneficial element in several crops enhancing growth and alleviating different biotic and abiotic stresses. Iron (Fe) deficiency stress in plants includes changes in the expression and the activity of certain antioxidative enzymes. Our previous study suggested the role of Si in alleviation of Fe deficiency stress by an increased root Fe acquisition (Pavlovic et al., 2013). MicroRNAs (miRNAs) are a class of endogenous small RNAs (21 to 24 nucleotides) playing a crucial role in the development of both plant and animals by down regulating gene expression at the post-transcriptional level. Here we studied the expression of miRNA398 and miRNA408 and its target gene superoxide dismutase (SOD) in Fe deficient cucumber (Cucumis sativus L.) plants grown with or without addition of Si. The expression of miRNAs and target gene was measured in roots, stems and leaves as well as in the leaves of different ages. lntercostal chlorosis in the young leaves was markedly decreased in the Si treatment. Plants treated with Si also showed increased expression of miRNA398 and miRNA408 in all organs, and consequently lower level of CuSOD transcripts. The expression of particular miRNAs followed this pattern; the highest level in the old fully developed leaves and the lowest level in young chlorotic leaves. Our results indicate that Si reduces (or at least respond on) the oxidative stress in Fe deficient cucumber plants on the posttranscriptional level mediated by miRNAs398 and 408

    Collaboration between research and teaching communities : implications for teacher education, practice, and policy making

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    In this paper, we aim to present the process of realization of a partnership between two professional communities in different countries devoted to supporting academic institutions in strengthening relationships between teacher education, educational research, and practice. Based on the current situation in the involved partners (academic institutions training pre-service and in-service teachers, school psychologists as well as researchers in psychology and education), we were facing the need to re-think how educational research, teacher education, and practice could be connected in a more useful and valuable way. In response to this, we tried to foster practiceled research activities in the partner institutions. Since the practice-led research approach is the hallmark of high-performing education systems, teachers, practitioners, and teacher educators need to research their practice, and young researchers should be prepared to foster carrying out practice-led research activities. Such an approach requires having capacities, motivation, confidence, and opportunities to do so. Consequently, the focus on practice-led research orientations needs to be modeled and sustained during the initial teacher education, but also in the context of training young researchers in educational sciences.peer-reviewe

    Fluorescence and chlorophyll content as indicators of the efficacy of plant extracts of Ambrosia artemisiifolia and Sorghum halepense in weed control

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    Efficient weed control is essential in agricultural production. However, bearing in mind the economic, environmental and health implications of classical chemical weed control, the aim of this study was to test the potential use of plant extract solutions for weed control in wheat. Plant extracts of two widespread and invasive weed species: Ambrosia artemisiifolia and Sorghum halepense were used to test the efficacy of these bioherbicides on three weed species common in wheat fields: Avena fatua, Bromus rigidus and Convolvulus arvensis. Parameters generally used for testing the efficacy of commercial herbicides: relative chlorophyll content, chlorophyll fluorescence and pigment content, were used to evaluate the efficacy of plant extract solutions, in a series of concentrations (1, 5, 10 and 20%). Results have shown that plant extracts of both tested species have negative effects on target weed species, with all tested concentrations of these solutions affecting the recorded parameters in B. rigidus and C. arvensis. However, as negative effects of A. artemisiifolia extract solutions were also documented on the crop plants, only plant extracts of S. halepense can be considered as a safe and efficient alternative option for weed control in wheat fields

    Therapeutic efficacy of mesenchymal stem cells for cardiovascular diseases

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    Despite the improvements in pharmacological and surgical treatments, cardiovascular diseases (CVDs) are the number one cause of death worldwide. During the last two decades, the search for new therapies has been revolutionized with the growing knowledge of stem cell biology. Due to their huge differentiation capacity and paracrine effects, mesenchymal stem cells (MSCs) are a promising tool for the treatment of CVDs. The encouraging outcomes of preclinical studies using MSCs as a treatment for diseased myocardium have set the scene for worldwide clinical trials. In this review, we overview either complete or ongoing clinical trials using MSCs for the therapy of CVDs. In particular, we analyze the biological properties of MSCs, elucidate recent clinical findings and clinical trial phases of investigation, highlight clinical therapeutic effects of MSCs, and discuss challenges towards the clinical use of these cells in the therapy of CVDs
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