Traditional uses of wild plants in Mardin central district and attached villages (Turkey)

This research reveals traditional uses of wild plants found in Artuklu district in Mardin Province in the Southeastern Anatolia Region of Turkey. This study, conducted between 2017 and 2019, gathered information on the medicinal and other uses of plant species traditionally used in Artuklu and the local names of these plants. Face to face surveys were conducted with 183 people in 91 neighbourhoods. The ethnobotanical uses of 125 plants belonging to 35 families, which are traditionally underutilized by the local people, have been recorded. Our results showed that the highest Relative Frequency of Citation (RFC) was recorded for the species Lathyrus pseudocicera Pamp. (0.32). 1 taxon is from Stereocaulaceae of Fungi, 2 taxa are from Pteridophyta and the others 122 taxa are from Magnoliophyta. In the region, plants mostly belonging to the families Fabaceae (21 taxa), Lamiaceae (11 taxa), Asteraceae (10 taxa) and Brassicaceae (10 taxa) were determined. The recorded ethnobotanical uses are for: food (64), medicinal (40), fodder (12), children's toys (5) and various other purposes (4). Due to the fact that Turkish, Kurdish, Arabic and Assyrian people have lived together in the Artuklu district, this ethnic diversity increased the use of wild plants and added richness. Preserving the coexistence of different cultural and religious groups in the research zone is essential for the maintenance of the rich wild plant local heritage

Expert opinion on patient journey, diagnosis and clinical monitoring in acid sphingomyelinase deficiency in Turkey: a pediatric metabolic disease specialist's perspective

This review by a panel of pediatric metabolic disease specialists aimed to provide a practical and implementable guidance document to assist clinicians in best clinical practice in terms of recognition, diagnosis and management of patients with acid sphingomyelinase deficiency (ASMD). The participating experts consider the clinical suspicion of ASMD by the physician to be of utmost importance in the prevention of diagnostic delay and strongly suggest the use of a diagnostic algorithm including/starting with dried blood spots assay in the timely diagnosis of ASMD in patients presenting with hepatosplenomegaly and a need for increased awareness among physicians in this regard to consider ASMD in the differential diagnosis. In anticipation of the introduction of enzyme replacement therapy, raising awareness of the disease among physicians to prevent diagnostic delay and further investigation addressing natural history of ASMD across the disease spectrum, potential presenting characteristics with a high index of suspicion, as well as biomarkers and genotype-phenotype correlations suggestive of poor prognosis seem important in terms of implementation of best practice patterns

Demographic, Phenotypic and Genotypic Features of Alkaptonuria Patients: A Single Centre Experience

Aim:Alkaptonuria (AKU) is an autosomal recessively inherited disease caused by a deficiency of homogentisate 1,2-dioxygenase. This enzyme converts homogentisic acid (HGA) into maleylacetoacetic acid in the tyrosine degradation pathway. The presence of HGA in urine, ochronosis (bluish-black pigmentation in connective tissues) and arthritis of the spine and the other large joints are the three major features of AKU. Nitisinone and a tyrosine-restricted diet are the treatment options. In this study, we evaluated the demographic and clinical characteristics and also the mutations of our AKU patients.Materials and Methods:This retrospective single centre study included 36 patients who were diagnosed as AKU between the years of 2002 and 2017 Çukurova University Faculty of Medicine, Department of Pediatrics, Division of Metabolism and Nutrition.Results:Thirty six AKU patients were included (17 female, 19 male) in our study. The mean age of the patients was 9.3±13.4 years (3 months-54 years). The major complaints were darkening of the urine (100%), ochronosis (11.1%), arthralgia (16.7%) and arthritis (8.1%). Darkening of the urine was firstly recognized at the age of 8.89±16.9 months (1-84 months). Eighteen (86%) patients had homozygous and 3 (14%) patients had compound heterozygous mutations in the HGD gene.Conclusion:AKU was the first inherited metabolic disease defined. The three main features are; darkening of the urine at birth which is followed by ochronosis (blue-dark pigmentation) clinically visible in the ear and alae of the nose and finally a severe ochronotic arthropathy of the spine and large joints at around the age of 50 years. Here we report on the clinical and genetic features of our patients at various ages

A 6-Month-Old Boy with Reddish, Scaly Skin: Netherton Syndrome

Typical features of Netherton syndrome are congenital ichthyosiform erythroderma, atopic diathesis and trichorrhexis nodosa. Here in this report, we present a case with congenital ichthyosis with atopy presenting later. We wanted to discuss the importance of whole exome sequencing to diagnose the atypical presentations of common syndromes

Pollen Morphological Investigations of Salvia L. In Southeastern of Turkey and Its Taxonomic Implication

In this study, the pollen morphology and exine structure of nine species of the genus Salvia L. (Lamiaceae) were investigated using light microscopy and scanning electron microscopy (SEM). Six micromorphological characters (pollen shape, polar length, equatorial width, exine and intine thickness, colpus length and colpus width) of pollen grains of Salvia have been identified. The palynological observations revealed that pollen grains of most studied taxa of Salvia were suboblate shape and possess hekzacolpate aperture. Tectal surface sculpture was a good criterion to identify particular taxa from Salvia. The pollen of which is characterized by reticulate, the pollen ornamentation was similar in all studied taxa

The anatomical characteristics of section Aethiopis (Lamiaceae) from Southeast, Turkey and their taxonomic implications

In this study, 4 Salvia species found in the Aethiopis section distributed in the province of Mardin in the Southeast of Turkey between the years 2018-2021 were analyzed comparatively in terms of anatomy. Transverse sections taken from the roots, stems, leaves, and petioles of the taxa were examined under a light microscope. S. brachyantha ssp. brachyantha, S. montbretii, S. palaestina, and S. syriaca taxa were analyzed anatomically. S. montbretii and S. syriaca species were analyzed in detail for the first time anatomically. In the anatomical examinations, it was observed that the root, stem, leaf, and petiole structures of the taxa were similar, but the shapes and sizes, in addition to the tissue layer and pith row numbers, were different. As a result, anatomical characters provide important information in the differentiation of species

Nutlet micromorphology of Mardin in Turkey Salvia L. (Lamiaceae) and its systematic implacations

The nutlet (mericarp) morphology of nine species of Salvia sect. Salvia (Salvia bracteata Banks & Sol., Salvia macrochlamys Boiss. & Kotschy, Salvia suffruticosa Montbret & Aucher ex Benth., Salvia trichoclada Benth.), Hymenosphace (Salvia multicaulis Vahl), Aethiopis (Salvia montbretii Benth., Salvia palaestina Benth., Salvia syriaca L.) and Hemisphace (Salvia russellii Benth.) (Lamiaceae) has been studied by scanning electron microscopy (SEM), and a detailed description of the nutlet morphological features of all examined taxa is provided. The basic shape of nutlets in most species is subprolate or prolate and the size ranged between 3.02 and 6.47 mm in length and between 1.78 and 5.10 mm in width. Three basic types of sculpturing can be distinguished: colliculate, reticulate and verrucate. The colliculate type is the most common among the studied species. The colliculate type is characteristic for sect. Salvia. Subsection Salvia with colliculate/slightly furrowed sculpturing is easily distinguished from the other subsections. The systematic and biological implications of the nutlet characteristics are shortly discussed. © 2021 Nordic Society Oikos. Published by John Wiley & Sons Lt

Mardin'de (Türkiye) Yayılış Gösteren İki Salvia L. Türü (Seksiyon Hymenosphace, Seksiyon Hemisphace) Üzerine Anatomik Araştırmalar

In this study, we investigated two Salvia species (sect. Hymenosphace, sect. Hemisphace) distributed in the province of Mardin in the Southeastern Anatolia Region in terms of anatomy. These species are S. multicaulis Vahl. (sect. Hymenosphace) and S. russellii Benth. (sect. Hemisphace). For anatomical investigation, cross-sections taken from roots, stems, leaves, and petioles of the taxa were examined under a light microscope. In anatomical examinations, it was observed that root, stem, leaf, and petiole structures of the taxa were similar but shapes and measurements as well as the the number of tissue layers and pith rows were different. In addition, it was observed that the surface of the S. multicaulis species was covered by multicellular and compound hairs. In conclusion, anatomical characters provide information of taxonomic importance, and especially hairiness is important in species differentiation.Bu çalışma Güneydoğu Anadolu Bölgesi'nde Mardin ilinde yayılış gösteren iki Salvia türü (Seksiyon Hymenosphace, Seksiyon Hemisphace) anatomik açıdan araştırılmıştır. Bu türler S. multicaulis Benth. (Seksiyon Hymenosphace) ve S. russellii V ahl. (Seksiyon Hemisphace)’dir. Anatomik inceleme için taksonların kök, gövde, yaprak ve petiollerinden alınan kesitler ışık mikroskobunda incelendi. Anatomik incelemelerde taksonların kök, gövde, yaprak ve petiyol yapılarının benzer olduğu ancak şekil ve ölçülerinin bunlarla beraber doku tabakası ve öz sıra sayılarının da farklı olduğu görüldü. Ayrıca anatomik analizlerde S. multicaulis türünün yüzeyinin çok hücreli ve bileşik tüylerle örtülü olduğu gözlendi. Sonuç olarak anatomik karakterler taksonomik öneme sahip bilgiler sağlar ve türlerin farklılaşmasında özellikle tüylülük önemlidir

The anatomical properties of Salvia section (Lamiaceae) in central district of Mardin (Turkey) and their taxonomic implications

In this study, 4 Salvia species found in the Salvia section distributed in the Artuklu district of Mardin province were analyzed comparatively in terms of anatomy. Plant specimens of Salvia section were collected from 11 localities. Anatomical studies were performed on specimens preserved in 70% alcohol. Transverse sections taken from the roots, stems, leaves, and petioles of the species were examined under a light microscope for anatomical examination. The anatomy of S. bracteata, S. macrochlamys, S. suffruticosa, S. trichoclada species were examined. The S. suffruticosa species was examined in detail for the first time anatomically. The data obtained as a result of the researches were compared with the previous studies on the Salvia section. In anatomical examinations, it was observed that the root, stem, leaf, and petiole structures of the taxa were similar but shapes and measurements in addition to this the number of tissue layers and pith rows are different. Also anatomically analyses, it has been seen that hairiness formed a difference between some species. As a result of all these discussed data, the anatomical characters such as number of ray rows in root, number of collenchyma layers in stem, mesophyll structures in leaves, shape of midrib and number of vascular bundles in petiole, provide important taxonomic information