1,429 research outputs found
As Time Goes By: The Long-Term Psychological Impact of either Regular Surveillance or Prophylactic Mastectomy in Women at Risk for Hereditary Breast Cancer
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer
death in women worldwide. In the Netherlands, approximately 13000 new breast
cancer cases are diagnosed annually, mostly occurring in women older than 50 years.
In total 12-13% (one in eight) of the women in the Netherlands will be diagnosed with
breast cancer during lifetime, and population screening for breast cancer therefore is
being offered to women as of 50 years of age. While the population risk of ovarian cancer
is 1.5% in the Netherlands, population screening is not offered.
It is estimated that 5-10% of all cancer cases are due to a genetic predisposition.
One of the first recognised entities was the clustering of breast and/or ovarian cancer in
families. A strong family history of breast (and/or ovarian) cancer in combination with
family members affected at a young age (below 50 years of age) may be suggestive of
a cancer susceptibility gene in the family. As of the beginning of the nineteen nineties
it became possible for women from families with clustering of breast (and/or ovarian)
cancer cases to opt for genetic counselling and testing, and subsequently to receive a
personal life time risk estimation. Depending on the risk estimation, decisions have to
be made for either regular surveillance or prophylactic surgery. Both options are associated
with pros and cons regarding on the one hand anxiety that cancer might develop
or be detected (at an advanced stage) during surveillance versus on the other hand
irreversible consequences after preventive surgery of either breasts and/or ovaries,
potentially affecting physical and psychological functioning. As of the beginning of the
availability of genetic testing, it became clear that more data on the (dis)advantages of
the different strategies was needed. More knowledge about the psychosocial consequences
of adhering to regular surveillance as well as prophylactic mastectomy and/or
salpingo-ovariectomy was essential, in order to adequately inform and support women
considering these options.
In 1999, two studies were initiated at the Erasmus University Medical Centre-Daniel
den
B. en C. t. Zwitserland, (EHRM, nrs. 889/19 en 43987/16) – Homoseksuele asielzoekers en niet-statelijke risico’s
Normconflict in de rechtspraak van het EHRM:EHRM 25 september 2012, <em>Rrapo t. Albanië</em>, nr. 58555/10
Dwang, verbod en grootse verwachtingen: over het falende Europese asielbeleid
April liet een spectaculaire daling zien van het aantal Syriërs dat in Nederland asiel vroeg: 101 tegen meer dan 5000 in oktober vorig jaar. Het lijkt erop dat de dichte grenzen in de Balkanlanden en het akkoord met Turkije over de terugname van asielzoekers de komst van Syrische vluchtelingen sterk hebben afgeremd. Is de vluchtelingen‘crisis’ opgelost? Allerminst: de deal met Turkije is kwetsbaar en bovendien juridisch kwestieus. Belangrijker is dat het Europese asielbeleid heeft aangetoond slecht te functioneren. Het is nu vooral zaak de gemeenschappelijke asielregels crisisbestendig te maken. Daarvoor lijkt echter de politieke steun te ontbreken
Europe and extraterritorial asylum
The book focuses on the legal
implications of external mechanisms of migration control for the
protection of refugees and irregular migrants. It defends the thesis
that when European states endeavor to control the movement of migrants
outside their territories, they remain responsible under international
law for upholding the rights of refugees and more general human rights.
The book explores how refugee and human rights law responds to a
phenomenon whereby states engage in external activity and seek
cooperation with other actors in the context of migration control; how
EU law governs and constrains the various types of pre-border migration
enforcement employed by the Member States of the European Union; and
examines the conformity with international law of current and unfolding
practices of external migration control.LEI Universiteit LeidenNWODe bescherming van fundamentele rechten in een integrerend Europ
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