13,206 research outputs found
Chromospheric polarimetry through multi-line observations of the 850 nm spectral region
Future solar missions and ground-based telescopes aim to understand the
magnetism of the solar chromosphere. We performed a supporting study in
Quintero Noda et al. (2016) focused on the infrared Ca II 8542 A line and we
concluded that is one of the best candidates because it is sensitive to a large
range of atmospheric heights, from the photosphere to the middle chromosphere.
However, we believe that it is worth to try improving the results produced by
this line observing additional spectral lines. In that regard, we examined the
neighbour solar spectrum looking for spectral lines that could increase the
sensitivity to the atmospheric parameters. Interestingly, we discovered several
photospheric lines that greatly improve the photospheric sensitivity to the
magnetic field vector. Moreover, they are located close to a second
chromospheric line that also belongs to the Ca II infrared triplet, i.e. the Ca
II 8498 A line, and enhances the sensitivity to the atmospheric parameters at
chromospheric layers. We conclude that the lines in the vicinity of the Ca II
8542 A line not only increase its sensitivity to the atmospheric parameters at
all layers, but also they constitute an excellent spectral window for
chromospheric polarimetry.Comment: 11 pages, 8 figures, 1 tabl
Charged Particles on Surfaces: Coexistence of Dilute Phases and Periodic Structures on Membranes
We consider a mixture of one neutral and two oppositely charged types of
molecules confined to a surface. Using analytical techniques and molecular
dynamics simulations, we construct the phase diagram of the system and exhibit
the coexistence between a patterned solid phase and a charge-dilute phase. The
patterns in the solid phase arise from competition between short-range
immiscibility and long-range electrostatic attractions between the charged
species. The coexistence between phases leads to observations of stable
patterned domains immersed in a neutral matrix background.Comment: 5 pages, 3 figure
Dissecting bombs and bursts: non-LTE inversions of low-atmosphere reconnection in SST and IRIS observations
Ellerman bombs and UV bursts are transient brightenings that are ubiquitously
observed in the lower atmospheres of active and emerging flux regions. Here we
present inversion results of SST/CRISP and CHROMIS, as well as IRIS data of
such transient events. Combining information from the Mg II h & k, Si IV and Ca
II 8542A and Ca II H & K lines, we aim to characterise their temperature and
velocity stratification, as well as their magnetic field configuration. We find
average temperature enhancements of a few thousand kelvin close to the
classical temperature minimum, but localised peak temperatures of up to
10,000-15,000 K from Ca II inversions. Including Mg II generally dampens these
temperature enhancements to below 8000 K, while Si IV requires temperatures in
excess of 10,000 K at low heights, but may also be reproduced with secondary
temperature enhancements of 35,000-60,000 K higher up. However, reproducing Si
IV comes at the expense of overestimating the Mg II emission. The line-of-sight
velocity maps show clear bi-directional jet signatures and strong correlation
with substructure in the intensity images, with slightly larger velocities
towards the observer than away. The magnetic field parameters show an
enhancement of the horizontal field co-located with the brightenings at similar
heights as the temperature increase. We are thus able to largely reproduce the
observational properties of Ellerman bombs with UV burst signature with
temperature stratifications peaking close to the classical temperature minimum.
Correctly modelling the Si IV emission in agreement with all other diagnostics
is, however, an outstanding issue. Accounting for resolution differences,
fitting localised temperature enhancements and/or performing spatially-coupled
inversions is likely necessary to obtain better agreement between all
considered diagnostics.Comment: Accepted for publication in Astronomy & Astrophysics. 24 pages, 17
figure
Chromospheric polarimetry through multi-line observations of the 850 nm spectral region II: A magnetic flux tube scenario
In this publication we continue the work started in Quintero Noda et al.
(2017) examining this time a numerical simulation of a magnetic flux tube
concentration. Our goal is to study if the physical phenomena that take place
in it, in particular, the magnetic pumping, leaves a specific imprint on the
examined spectral lines. We find that the profiles from the interior of the
flux tube are periodically dopplershifted following an oscillation pattern that
is also reflected in the amplitude of the circular polarization signals. In
addition, we analyse the properties of the Stokes profiles at the edges of the
flux tube discovering the presence of linear polarization signals for the Ca II
lines, although they are weak with an amplitude around 0.5% of the continuum
intensity. Finally, we compute the response functions to perturbations in the
longitudinal field and we estimate the field strength using the weak field
approximation. Our results indicate that the height of formation of the
spectral lines changes during the magnetic pumping process which makes the
interpretation of the inferred magnetic field strength and its evolution more
difficult. These results complement those from previous works demonstrating the
capabilities and limitations of the 850 nm spectrum for chromospheric Zeeman
polarimetry in a very dynamic and complex atmosphere.Comment: 12 pages, 12 figures, 0 tables, MNRAS main journal publicatio
Magnetic order and the electronic ground state in the pyrochlore iridate Nd2Ir2O7
We report a combined muon spin relaxation/rotation, bulk magnetization,
neutron scattering, and transport study of the electronic properties of the
pyrochlore iridate Nd2Ir2O7. We observe the onset of strongly hysteretic
behavior in the temperature dependent magnetization below 120 K, and an abrupt
increase in the temperature dependent resistivity below 8 K. Zero field muon
spin relaxation measurements show that the hysteretic magnetization is driven
by a transition to a magnetically disordered state, and that below 8 K a
complex magnetically ordered ground state sets in, as evidenced by the onset of
heavily damped spontaneous muon precession. Our measurements point toward the
absence of a true metal-to-insulator phase transition in this material and
suggest that Nd2Ir2O7 lies either within or on the metallic side of the
boundary of the Dirac semimetal regime within its topological phase diagram.Comment: 21 pages, 7 figure
Chromospheric polarimetry through multi-line observations of the 850 nm spectral region III: Chromospheric jets driven by twisted magnetic fields
We investigate the diagnostic potential of the spectral lines at 850 nm for
understanding the magnetism of the lower atmosphere. For that purpose, we use a
newly developed 3D simulation of a chromospheric jet to check the sensitivity
of the spectral lines to this phenomenon as well as our ability to infer the
atmospheric information through spectropolarimetric inversions of noisy
synthetic data. We start comparing the benefits of inverting the entire
spectrum at 850 nm versus only the Ca II 8542 A spectral line. We found a
better match of the input atmosphere for the former case, mainly at lower
heights. However, the results at higher layers were not accurate. After several
tests, we determined that we need to weight more the chromospheric lines than
the photospheric ones in the computation of the goodness of the fit. The new
inversion configuration allows us to obtain better fits and consequently more
accurate physical parameters. Therefore, to extract the most from multi-line
inversions, a proper set of weights needs to be estimated. Besides that, we
conclude again that the lines at 850 nm, or a similar arrangement with Ca II
8542 A plus Zeeman sensitive photospheric lines, poses the best observing
configuration for examining the thermal and magnetic properties of the lower
solar atmosphere.Comment: 14 pages, 11 figure
First order phase transition from the vortex liquid to an amorphous solid
We present a systematic study of the topology of the vortex solid phase in
superconducting BiSrCaCuO samples with low doses of
columnar defects. A new state of vortex matter imposed by the presence of
geometrical contours associated with the random distribution of columns is
found. The results show that the first order liquid-solid transition in this
vortex matter does not require a structural symmetry change.Comment: 4 pages, 5 figure
Randomized phase II study of fulvestrant plus palbociclib or placebo in endocrine-sensitive, hormone receptor-positive/HER2–advanced breast cancer: GEICAM/2014–12 (FLIPPER)
Background
The potential benefit of adding palbociclib to fulvestrant as first-line treatment in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative endocrine-sensitive advanced breast cancer (ABC) patients remains uncharacterized.
Patients and methods
In this randomized (1:1), double-blind, phase II study, postmenopausal women with HR-positive, HER2-negative ABC with de novo metastatic disease or those who relapsed after >12 months of adjuvant endocrine therapy received palbociclib/fulvestrant or placebo/fulvestrant. Stratification was based on recurrent versus de novo metastatic disease and visceral involvement. The primary objective was one-year progression-free survival (PFS-1y) rate. The sample size was 190 patients. The two-sided alpha of 0.2, 80% of power to detect a difference between the arms, assuming PFS rates of 0.695 and 0.545 for palbociclib/fulvestrant and placebo/fulvestrant, respectively.
Results
In total, 189 patients were randomized to palbociclib/fulvestrant ([n = 94] or placebo/fulvestrant [n = 95]). 45.5% and 60.3% of patients had de novo metastatic disease and visceral involvement, respectively. PFS-1y rates were 83.5% and 71.9% in the palbociclib/fulvestrant and placebo/fulvestrant arms, (HR 0.55, 80% CI 0.36–0.83, P = 0.064). The median PFS were 31.8 and 22.0 months for the palbociclib/fulvestrant and placebo/fulvestrant arms (aHR 0.48, 80% CI 0.37–0.64, P = 0.001).
The most frequent grade 3–4 adverse events were neutropenia (68.1% vs. 0%), leucopenia (26.6% vs. 0%), anemia (3.2% vs. 0%), and lymphopenia (14.9% vs. 2.1%) for the palbociclib/fulvestrant and placebo/fulvestrant, respectively. The most frequent non-hematologic grade 3–4 adverse event was fatigue (4.3% vs. 0%).
Conclusions
Palbociclib/fulvestrant demonstrated better PFS-1y rates and median PFS than placebo/fulvestrant in HR-positive/HER2-negative endocrine-sensitive ABC patients
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