Radiant waste heat recovery from steelmaking and glass industry

This paper tackles the problem of industrial waste heat recovery through an unexploited heat transfer mechanism: thermal radiation. Energy intensive industries have a considerable potential of unused radiant heat, which cannot be recovered through existing methods. That potential energy is quantified for the main identified industries: steel and glassmaking. Then, a radiant heat capturing device allowing high temperature heat capture is designed according to process requirements. Finally, recoverable heat is estimated and potential uses are proposed

Design of a Radiant Heat Capturing Device for Steel Mills

This paper approaches the energy transition towards decarbonization and lower primary energy use in the steel and glass industries through the exploitation of radiant waste heat. In contrast with exhaust gases heat recovery, radiant waste heat has typically not been used. This energy waste is found in energy intensive processes in which high temperatures are reached. For instance, in the steel making process, the cast steel is red hot and emits a considerable amount of radiant energy. In this paper the conceptual design of a radiant heat capturing device is presented. This device enables the recovery of currently unused energy while solving the radiative emission-related problems. The achieved design gets to an optimized solution regarding view factors and optical properties of the involved surfaces. In this research work, those factors are optimized to maximize the amount of heat recovered by the presented device. Simulation tools are used to test different designs and define the most appropriate solution for a given case.This work has been performed under BEROA-GO project (Waste Heat Collection from Solids for Efficient and Competitive Use), granted by the Basque Government (Spain), exp. KK-2017/00060

Association of TYR SNP rs1042602 with Melanoma Risk and Prognosis

Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated with melanoma progression. Thus, after exome sequencing of a set of melanoma patients and healthy control individuals, we identified rs1042602, an SNP within TYR, as a good candidate. After genotyping rs1042602 in 1025 patients and 773 healthy donors, we found that the rs1042602-A allele was significantly associated with susceptibility to melanoma (CATT test: p = 0.0035). Interestingly, we also observed significant differences between patients with good and bad prognosis (5 years of follow-up) (n = 664) (CATT test for all samples p = 0.0384 and for men alone p = 0.0054). Disease-free-survival (DFS) analyses also showed that patients with the A allele had shorter DFS periods. In men, the association remained significant even in a multivariate Cox Proportional-hazards model, which was adjusted for age at diagnosis, Breslow thickness, ulceration and melanoma subtype (HR 0.4; 95% confidence interval (CI) 0.20–0.83; p = 0.0139). Based on our results, we propose that rs1042602-A is a risk allele for melanoma, which also seems to be responsible for a poorer prognosis of the disease, particularly in men

GLP-1 limits adipocyte inflammation and its low circulating pre-operative concentrations predict worse type 2 diabetes remission after bariatric surgery in obese patients

Objective: Glucagon-like peptide (GLP)-1 has been proposed as a key candidate in glucose improvements after bariatric surgery. Our aim was to explore the role of GLP-1 in surgically-induced type 2 diabetes (T2D) improvement and its capacity to regulate human adipocyte inflammation. Methods: Basal circulating concentrations of GLP-1 as well as during an oral glucose tolerance test (OGTT) were measured in lean and obese volunteers with and without T2D (n = 93). In addition, GLP-1 levels were determined before and after weight loss achieved by Roux-en-Y gastric bypass (RYGB) (n = 77). The impact of GLP-1 on inflammation signalling pathways was also evaluated. Results: We show that the reduced (p < 0.05) circulating levels of GLP-1 in obese T2D patients increased (p < 0.05) after RYGB. The area under the curve was significantly lower in obese patients with (p < 0.01) and without (p < 0.05) T2D compared to lean volunteers while obese patients with T2D exhibited decreased GLP-1 levels at baseline (p < 0.05) and 120 min (p < 0.01) after the OGTT. Importantly, higher (p < 0.05) pre-operative GLP-1 concentrations were found in patients with T2D remission after RYGB. We also revealed that exendin-4, a GLP-1 agonist, downregulated the expression of inflammation-related genes (IL1B, IL6, IL8, TNF) and, conversely, upregulated the mRNA levels of ADIPOQ in human visceral adipocytes. Furthermore, exendin-4 blocked (p < 0.05) LPS-induced inflammation in human adipocytes via downregulating the expression and secretion of key inflammatory markers. Conclusions: Our data indicate that GLP-1 may contribute to glycemic control and exert a role in T2D remission after RYGB. GLP-1 is also involved in limiting inflammation in human visceral adipocytes

Análisis de sistemas binarios con período variable

Estarnos llevando a cabo un monitoreo fotomètrico de una muestra de sistemas binarios eclipsantes con período variable, considerados preliminarmente como semiseparados o en contacto, a fin de determinar sus parámetros astrofísicos fundamentales y caracterizar la interacción entre sus componentes. En este trabajo presentamos las curvas de luz de cuatro sistemas y el modelado de dos de ellas. Verificamos que la fotometría obtenida es adecuada para los objetivos del proyecto. Conjuntamente presentamos la primera clasificación espectral de siete de estos sistemas.We are conducting a photometric monitoring of a sample of eclipsing binary systems with variable periods, preliminarly considered as semidetached or in contact. We aim at determining the fundamental astrophysical parameters of these objects and at characterizing the interactions between their components. In this work we present the light curves of four systems and the modeling of two of them. The photometry has revealed to be adequate for the project purposes. We also report the first spectral classification of seven systems from the sample.Facultad de Ciencias ExactasInstituto de Astrofísica de La Plat

Análisis de sistemas binarios con período variable

Estarnos llevando a cabo un monitoreo fotomètrico de una muestra de sistemas binarios eclipsantes con período variable, considerados preliminarmente como semiseparados o en contacto, a fin de determinar sus parámetros astrofísicos fundamentales y caracterizar la interacción entre sus componentes. En este trabajo presentamos las curvas de luz de cuatro sistemas y el modelado de dos de ellas. Verificamos que la fotometría obtenida es adecuada para los objetivos del proyecto. Conjuntamente presentamos la primera clasificación espectral de siete de estos sistemas.We are conducting a photometric monitoring of a sample of eclipsing binary systems with variable periods, preliminarly considered as semidetached or in contact. We aim at determining the fundamental astrophysical parameters of these objects and at characterizing the interactions between their components. In this work we present the light curves of four systems and the modeling of two of them. The photometry has revealed to be adequate for the project purposes. We also report the first spectral classification of seven systems from the sample.Facultad de Ciencias ExactasInstituto de Astrofísica de La Plat

Análisis de sistemas binarios con período variable

Estarnos llevando a cabo un monitoreo fotomètrico de una muestra de sistemas binarios eclipsantes con período variable, considerados preliminarmente como semiseparados o en contacto, a fin de determinar sus parámetros astrofísicos fundamentales y caracterizar la interacción entre sus componentes. En este trabajo presentamos las curvas de luz de cuatro sistemas y el modelado de dos de ellas. Verificamos que la fotometría obtenida es adecuada para los objetivos del proyecto. Conjuntamente presentamos la primera clasificación espectral de siete de estos sistemas.We are conducting a photometric monitoring of a sample of eclipsing binary systems with variable periods, preliminarly considered as semidetached or in contact. We aim at determining the fundamental astrophysical parameters of these objects and at characterizing the interactions between their components. In this work we present the light curves of four systems and the modeling of two of them. The photometry has revealed to be adequate for the project purposes. We also report the first spectral classification of seven systems from the sample.Facultad de Ciencias ExactasInstituto de Astrofísica de La Plat