Making the Self in a Material World: Food and Moralities of Consumption

Food is increasingly central to consumer culture today. From fine dining restaurants to farmers’ markets, stainless steel kitchenware to celebrity chef cookbooks, there is a stylish array of culinary commodities available for fashioning our identities. Yet this occurs at a time when commodity consumption more generally is under greater question as a site of self-making, with the rise of anti-consumerist sentiment. This article examines how people negotiate these issues in their identity formation, by focusing on those for whom food is central to their sense of self: ‘foodies’. I draw on theories of consumption, identity and material culture, in particular the work of Daniel Miller, to examine ethnographic research undertaken with foodies in Melbourne, Australia

Food Cultures: Introduction

An introduction to the themes of the 'Food Cultures' section and an overview of the essays within

Ação de rizobactérias sobre fungos fitopatogênicos

Although tumor-associated macrophages have been extensively studied in the control of response to radiotherapy, the molecular mechanisms involved in the ionizing radiation-mediated activation of macrophages remain elusive. Here we show that ionizing radiation induces the expression of interferon regulatory factor 5 (IRF5) promoting thus macrophage activation toward a pro-inflammatory phenotype. We reveal that the activation of the ataxia telangiectasia mutated (ATM) kinase is required for ionizing radiation-elicited macrophage activation, but also for macrophage reprogramming after treatments with γ-interferon, lipopolysaccharide or chemotherapeutic agent (such as cisplatin), underscoring the fact that the kinase ATM plays a central role during macrophage phenotypic switching toward a pro-inflammatory phenotype through the regulation of mRNA level and post-translational modifications of IRF5. We further demonstrate that NADPH oxidase 2 (NOX2)-dependent ROS production is upstream to ATM activation and is essential during this process. We also report that the inhibition of any component of this signaling pathway (NOX2, ROS and ATM) impairs pro-inflammatory activation of macrophages and predicts a poor tumor response to preoperative radiotherapy in locally advanced rectal cancer. Altogether, our results identify a novel signaling pathway involved in macrophage activation that may enhance the effectiveness of radiotherapy through the reprogramming of tumor-infiltrating macrophages