The Kerr-Newman-Godel Black Hole

By applying a set of Hassan-Sen transformations and string dualities to the Kerr-Godel solution of minimal D=5 supergravity we derive a four parameter family of five dimensional solutions in type II string theory. They describe rotating, charged black holes in a rotating background. For zero background rotation, the solution is D=5 Kerr-Newman; for zero charge it is Kerr-Godel. In a particular extremal limit the solution describes an asymptotically Godel BMPV black hole.Comment: 12 pages, LaTeX, no figures; v2: one reference added, very minor changes; to appear in CQ

Cosmological tachyon from cubic string field theory

The classical dynamics of the tachyon scalar field of cubic string field theory is considered on a cosmological background. Starting from a nonlocal action with arbitrary tachyon potential, which encodes the bosonic and several supersymmetric cases, we study the equations of motion in the Hamilton-Jacobi formalism and with a generalized Friedmann equation, appliable in braneworld or modified gravity models. The cases of cubic (bosonic) and quartic (supersymmetric) tachyon potential in general relativity are automatically included. We comment the validity of the slow-roll approximation, the stability of the cosmological perturbations, and the relation between this tachyon and the Dirac-Born-Infeld one.Comment: 20 pages JHEP style, 1 figure; v4: misprints corrected, matches the published versio

Selective digestive and oropharyngeal decontamination in medical and surgical ICU patients:individual patient data meta-analysis

Objectives: Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) improved intensive care unit (ICU), hospital and 28-day survival in ICUs with low levels of antibiotic resistance. Yet it is unclear whether the effect differs between medical and surgical ICU patients.& para;& para;Methods: In an individual patient data meta-analysis, we systematically searched PubMed and included all randomized controlled studies published since 2000. We performed a two-stage meta-analysis with separate logistic regression models per study and per outcome (hospital survival and ICU survival) and subsequent pooling of main and interaction effects.& para;& para;Results: Six studies, all performed in countries with low levels of antibiotic resistance, yielded 16 528 hospital admissions and 17 884 ICU admissions for complete case analysis. Compared to standard care or placebo, the pooled adjusted odds ratios for hospital mortality was 0.82 (95% confidence interval (CI) 0.72-0.93) for SDD and 0.84 (95% CI 0.73-0.97) for SOD. Compared to SOD, the adjusted odds ratio for hospital mortality was 0.90 (95% CI 0.82-0.97) for SDD. The effects on hospital mortality were not modified by type of ICU admission (p values for interaction terms were 0.66 for SDD and control, 0.87 for SOD and control and 0.47 for SDD and SOD). Similar results were found for ICU mortality.& para;& para;Conclusions: In ICUs with low levels of antibiotic resistance, the effectiveness of SDD and SOD was not modified by type of ICU admission. SDD and SOD improved hospital and ICU survival compared to standard care in both patient populations, with SDD being more effective than SOD. (C) 2017 The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases

Stable de Sitter vacua in N=2, D=5 supergravity

We find 5D gauged supergravity theories exhibiting stable de Sitter vacua. These are the first examples of stable de Sitter vacua in higher-dimensional (D>4) supergravity. Non-compact gaugings with tensor multiplets and R-symmetry gauging seem to be the essential ingredients in these models. They are however not sufficient to guarantee stable de Sitter vacua, as we show by investigating several other models. The qualitative behaviour of the potential also seems to depend crucially on the geometry of the scalar manifold.Comment: 26 pages, v2:typos corrected, published versio

Selection and transfer of an IncI1-tet(A) plasmid of Escherichia coli in an ex vivo model of the porcine caecum at doxycycline concentrations caused by cross-contaminated feed

Aims: The aim of this study was to investigate the effect of subtherapeutic intestinal doxycycline (DOX) concentrations (4 and 1mgl(-1)), caused by cross-contamination of feed, on the enrichment of a DOX-resistant commensal Escherichia coli and its resistance plasmid in an exvivo model of the porcine caecum. Methods and Results: A DOX-resistant, tet(A)-carrying, porcine commensal E.coli strain (EC 682) was cultivated for 6days in the porcine caecum model under different conditions (0, 1 and 4mgl(-1) DOX). EC 682, other coliforms and anaerobic bacteria were enumerated daily. A selection of isolated DOX-resistant coliforms (n=454) was characterized by rep-PCR clustering, PCR assays (Inc1 and tet(A)) and micro broth dilution susceptibility tests (Sensititre). Both 1 and 4mgl(-1) DOX-enriched medium had a significantly higher selective effect on EC 682 and other resistant coliforms than medium without DOX. Transconjugants of EC 682 were isolated more frequently in the presence of 1 and 4mgl(-1) DOX compared to medium without DOX. Conclusions: Subtherapeutic intestinal DOX concentrations have the potential to select for DOX-resistant E.coli, and promote the selection of transconjugants in a porcine caecum model. Significance and Impact of the Study: Cross-contamination of feed with antimicrobials such as DOX likely promotes the spread of antimicrobial resistance. Therefore, it is important to develop or fine-tune guidelines for the safe use of antimicrobials in animal feed and its storage

Fundamental Strings in Open String Theory at the Tachyonic Vacuum

We show that the world-volume theory on a D-p-brane at the tachyonic vacuum has solitonic string solutions whose dynamics is governed by the Nambu-Goto action of a string moving in (25+1) dimensional space-time. This provides strong evidence for the conjecture that at this vacuum the full (25+1) dimensional Poincare invariance is restored. We also use this result to argue that the open string field theory at the tachyonic vacuum must contain closed string excitations.Comment: LaTeX file, 16 pages, references and clarification adde

Tits-Satake projections of homogeneous special geometries

We organize the homogeneous special geometries, describing as well the couplings of D=6, 5, 4 and 3 supergravities with 8 supercharges, in a small number of universality classes. This relates manifolds on which similar types of dynamical solutions can exist. The mathematical ingredient is the Tits-Satake projection of real simple Lie algebras, which we extend to all solvable Lie algebras occurring in these homogeneous special geometries. Apart from some exotic cases all the other, 'very special', homogeneous manifolds can be grouped in seven universality classes. The organization of these classes, which capture the essential features of their basic dynamics, commutes with the r- and c-map. Different members are distinguished by different choices of the paint group, a notion discovered in the context of cosmic billiard dynamics of non maximally supersymmetric supergravities. We comment on the usefulness of this organization in universality classes both in relation with cosmic billiard dynamics and with configurations of branes and orbifolds defining special geometry backgrounds.Comment: 65 pages, LaTeX; v2: added reference; v3: small corrections, section 3.3 modifie