Biodiversity of Antarctic nematodes: the ‘NEMASLAN’ project

Recent biodiversity research reveals that more than 50% of the free-living marine nematode species found in before unexplored environments, such as Antarctica, are new to science. Too few taxonomists remain to describe them all. Additionally, there are problems with the quality control of the identification of nematode samples since fewer labs possess all the literature (and manpower) required to verify the morphological characteristics of the animals.NEMASLAN, software for a tree-based classification system (Access) is a methodological approach for improving identification, classification and description of specimens in difficult taxonomic groups such as free-living marine nematodes. It seeks to serve as an easy research tool for central management of information of the taxon of the nematodes, and this for people with little training in database technologies.The program consists of four main modules: (see demonstration)1. Module for data- entering: provides possibilities to enter geographic, morphological, ecological, and literature data on species in a record database. An additional connection between these database records and the actual digital sources (e.g. scanned literature from original descriptions and good recent publications) enlarges the scientific value of the system.Personal metadatasets can be created, for example for the use of drawings and/or pictures of undescribed species or not yet published taxonomic papers. 2. Module for document consultation: data sources (PDF documents of original descriptions, text documents, photographs,…) and their references can be consulted. 3. Module for Quick Search: Morphological data from the species identification (e.g. shape and/or position of amphid, cuticle, buccal cavity, tail, oesophagus, caudal glands and spinneret; feeding type; numerical fields of de Man ratios, length, setae, nerve ring, excretory porus, spicule, gubernaculum, male supplements) and other information such as type of biotope and water depth distribution can be consulted; datasheets can be generated.4. Search Module: The output and search within the database can be user configured (i.e. questions like ‘give me all the nematode species so far described from the coastal sites with a spicule longer than 30µm and cuticular punctuations’ get an answer from this database). SQL (Structured Query Language) is the formal language used to query databases. An in-depth knowledge of the fairly complex SQL language is not required.The Windows application functions for multi-users in a local network environment (LAN). The program is distributed free of charge through a website (at present http://allserv.rug.ac.be/~tdeprez: later on through a more specified Antarctic database website) at which demonstration datasets are distributed.NEMASLAN was applied to Antarctic nematodes. The resulting ‘Biodiversity of Antarctic Nematodes’ CD-ROM version includes an archive of all numerical and nominal information for each species ever described in the Southern Ocean. About 350 species have thus been digitized. There is an urgent need to develop appropriate information tools on Antarctic marine biodiversity for scientific, environmental management and conservation purposes. Therefore, the collaboration of three laboratory pioneers in Antarctic biodiversity databases (e.g. Antarctic nematodes, amphipods and echinids, see other presentations) will seek for further developments such as the construction of a common portal, common mapping applications, or links to pertinent information sources of Antarctic benthic biodiversity. The resulting ‘biodiversity information system’ will be made available to the scientific community. This will be done within the framework of the OSTC project on Antarctica - BIANZO (BIodiversity of three representative groups of the ANtarctic ZOobenthos). It will contribute to the DIVERSITAS, SA 2000, CoML-OBIS and GBIF initiatives

Nematoda - free living

The list was compiled by Guy De Smet, a non-specialist, who was assisted by nematologists Magda Vincx, Ann Vanreusel, Sandra Vanhove, Jan Vanaverbeke and Maaike Steyaert. Dr. F. Riemann gave useful advice for the genus Daptonema. The classification in the list is based upon Lorenzen (1979, 1994). Information on the geographic distribution in the list is based upon Gerlach and Riemann (1973, 1974), Platt and Warwick (1983, 1988) and Warwick et al. (1998).ReferencesLorenzen, S. Entwürf eines Phylogenetischen Systems der Freilebenden Nematoden, Kiel, 1979.Lorenzen, S. The Phylogenetic Systematics of Freeliving Nematodes, The Ray Society, 1994.Gerlach, S. A. and Riemann, F. The Bremerhaven Checklist of Aquatic Nematodes. Veröffentlichungen des Instituts für Meeresforschung in Bremerhaven, Supplement 4, (Heft 1 1973, Heft 2 1974).Platt, H. M. and Warwick, R. M. Free-living Marine Nematodes (Part I British Enoplids) Synopses of the British Fauna (New series) No. 28, 1983.Platt, H. M. and Warwick, R. M. Free-living Marine Nematodes (Part II British Chromadorids) Synopses of the British Fauna (New series) No. 38, 1988.Warwick, R. M., Platt, H. M. and Somerfield, P. J. Free-living Marine Nematodes (Part III Monhysterids) Synopses of the British Fauna (New series) No. 53, 1998.</ul

Становлення та функціонування сучасних наукових шкіл

Background. Several studies have shown that the use of selective digestive tract decontamination (SDD) reduces mortality. However, fear for increasing multidrug resistance might prevent wide acceptance. A survey was performed among the units registered in the European Registry for Intensive Care (ERIC), in order to investigate the number of ICUs using SDD and the factors that prevented the use of SDD. Methods. One invitation to the electronic survey was sent to each ERIC unit. The survey focused on department characteristics (intensive care type, local resistance levels), local treatment modalities (antibiotic stewardship) and doctors' opinions (collaborative issues concerning SDD). All ICU's in countries participating in the European Centre for Disease Prevention and Control resistance surveillance program were analysed. Results. Seventeen percent of the ICUs registered in the ERIC database used SDD prophylaxis. Most of these ICUs were located in the Netherlands or Germany. ICUs using SDD were four times more likely to use antibiotic stewardship. Also larger ICUs were more likely to use SDD. On the contrary, resistance to antibiotics was not related to the use of SDD. Also the doctor's opinion that SDD is proven in duster-randomized trials was not a determinant for not using SDD. Conclusion. SDD is used in a minority of the European ICUs registered in the ERIC database. Larger ICUs and ICUs with a prudent antibiotic policy were more likely to use SDD. Neither antibiotic resistance nor the duster randomized study design were determinants of the non-use of SDD

Communication during counseling sessions about inhaled corticosteroids at the community pharmacy

Contains fulltext : 172163.pdf (publisher's version ) (Open Access)BACKGROUND: Pharmaceutical care is one of the major tasks of pharmacists, which aims to improve patient outcomes. Counseling patients with asthma or chronic obstructive pulmonary disease about their use of inhaled corticosteroids (ICS) might enhance medication adherence and symptom control. Therefore, effective pharmacist-patient communication is very important. In this regard, both affective communication, for handling emotions, and instrumental communication, for exchanging biomedical and lifestyle information, are relevant. Until now, only few studies have explored pharmacist-patient communication, and further insight is needed in this regard. The aim of this study is to investigate how pharmacists and pharmacy technicians communicate about ICS with patients with asthma and/or chronic obstructive pulmonary disease, what topics are discussed by them, and whether pharmacists and pharmacy technicians differ in their communication during counseling sessions. METHODS: Patients aged >/=18 years who had used ICS for at least 1 year and filled at least two ICS prescriptions in the preceding year were recruited through 12 pharmacies. Participants had one counseling session with a pharmacist or a pharmacy technician, which was video-recorded. The process and content of the provider-patient communication were analyzed using the Roter interaction analysis system, adapted to the pharmaceutical setting. RESULTS: A total of 169 sessions were recorded and analyzed. The communication appeared largely instrumental. Lifestyle, psychosocial issues, and ICS adherence were not discussed in detail. The pharmacists had longer conversations and more affective talk than the pharmacy technicians. CONCLUSION: Pharmacists and pharmacy technicians may need to pay more attention to ICS adherence, lifestyle, and psychosocial topics. They differed in their communication; the pharmacists exhibited more affective behavior and discussed medical and therapeutic issues more extensively compared to the pharmacy technicians. Educational courses for pharmacists and pharmacy technicians could focus more on the discussion of adherence, lifestyle, and psychosocial topics with patients

Cosmological tachyon from cubic string field theory

The classical dynamics of the tachyon scalar field of cubic string field theory is considered on a cosmological background. Starting from a nonlocal action with arbitrary tachyon potential, which encodes the bosonic and several supersymmetric cases, we study the equations of motion in the Hamilton-Jacobi formalism and with a generalized Friedmann equation, appliable in braneworld or modified gravity models. The cases of cubic (bosonic) and quartic (supersymmetric) tachyon potential in general relativity are automatically included. We comment the validity of the slow-roll approximation, the stability of the cosmological perturbations, and the relation between this tachyon and the Dirac-Born-Infeld one.Comment: 20 pages JHEP style, 1 figure; v4: misprints corrected, matches the published versio

Selective digestive and oropharyngeal decontamination in medical and surgical ICU patients:individual patient data meta-analysis

Objectives: Selective digestive decontamination (SDD) and selective oropharyngeal decontamination (SOD) improved intensive care unit (ICU), hospital and 28-day survival in ICUs with low levels of antibiotic resistance. Yet it is unclear whether the effect differs between medical and surgical ICU patients.& para;& para;Methods: In an individual patient data meta-analysis, we systematically searched PubMed and included all randomized controlled studies published since 2000. We performed a two-stage meta-analysis with separate logistic regression models per study and per outcome (hospital survival and ICU survival) and subsequent pooling of main and interaction effects.& para;& para;Results: Six studies, all performed in countries with low levels of antibiotic resistance, yielded 16 528 hospital admissions and 17 884 ICU admissions for complete case analysis. Compared to standard care or placebo, the pooled adjusted odds ratios for hospital mortality was 0.82 (95% confidence interval (CI) 0.72-0.93) for SDD and 0.84 (95% CI 0.73-0.97) for SOD. Compared to SOD, the adjusted odds ratio for hospital mortality was 0.90 (95% CI 0.82-0.97) for SDD. The effects on hospital mortality were not modified by type of ICU admission (p values for interaction terms were 0.66 for SDD and control, 0.87 for SOD and control and 0.47 for SDD and SOD). Similar results were found for ICU mortality.& para;& para;Conclusions: In ICUs with low levels of antibiotic resistance, the effectiveness of SDD and SOD was not modified by type of ICU admission. SDD and SOD improved hospital and ICU survival compared to standard care in both patient populations, with SDD being more effective than SOD. (C) 2017 The Author(s). Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases

Multilinear Wavelets: A Statistical Shape Space for Human Faces

We present a statistical model for $3$D human faces in varying expression, which decomposes the surface of the face using a wavelet transform, and learns many localized, decorrelated multilinear models on the resulting coefficients. Using this model we are able to reconstruct faces from noisy and occluded $3$D face scans, and facial motion sequences. Accurate reconstruction of face shape is important for applications such as tele-presence and gaming. The localized and multi-scale nature of our model allows for recovery of fine-scale detail while retaining robustness to severe noise and occlusion, and is computationally efficient and scalable. We validate these properties experimentally on challenging data in the form of static scans and motion sequences. We show that in comparison to a global multilinear model, our model better preserves fine detail and is computationally faster, while in comparison to a localized PCA model, our model better handles variation in expression, is faster, and allows us to fix identity parameters for a given subject.Comment: 10 pages, 7 figures; accepted to ECCV 201

The Kerr-Newman-Godel Black Hole

By applying a set of Hassan-Sen transformations and string dualities to the Kerr-Godel solution of minimal D=5 supergravity we derive a four parameter family of five dimensional solutions in type II string theory. They describe rotating, charged black holes in a rotating background. For zero background rotation, the solution is D=5 Kerr-Newman; for zero charge it is Kerr-Godel. In a particular extremal limit the solution describes an asymptotically Godel BMPV black hole.Comment: 12 pages, LaTeX, no figures; v2: one reference added, very minor changes; to appear in CQ

Drug Shortages From the Perspectives of Authorities and Pharmacy Practice in the Netherlands: An Observational Study

Background: Drug shortages are a potential threat to public health. Reliable data on drug shortages is limited. The objective was to examine the extent and nature of potential drug shortages signaled by authorities and pharmacy practice in the NetherlandsMaterials and Methods: The primary working systems of Dutch authorities (Medicines Evaluation Board and Health and Youth Care Inspectorate) and the archives of pharmacy practice (Royal Dutch Pharmacists Association) from 2012 to 2015 were searched for number, characteristics, overlap, and date of signals on potential drug shortages. Also, the product characteristics of the potential drug shortages were analyzed from the two different sourcesResults: Authorities detected 2.6 times more signals on potential shortages than pharmacy practice. Only 438 (8%) out of 5,731 potential drug shortages were detected by both authorities and pharmacy practice. Signals were detected later by authorities than by pharmacy practice, especially on potential permanent shortages (median difference −180 days (IQR: −4 to −405 days)). Authorities detected by majority (72%) signals related to permanent shortages with relative overrepresentation of rectal products and anti-infectives for systemic use. In contrast, pharmacy practice detected by majority (71%) signals related to temporary shortages with relative overrepresentation of ocular and cutaneous products, anti-infectives for systemic use, products for sensory organs and dermatologicals.Conclusions: Authorities and pharmacy practice detected different signals on potential drug shortages with little overlap. Combining data from both authorities and pharmacy practice seems to be necessary in order to gain a more complete overview and maximum insight in potential drug shortages at a national level. Moreover, the finding that authorities were informed later than pharmacy practice causes concerns in terms of opportunities for authorities to assist pharmacy practice to find solutions for shortages