40 research outputs found

    Violencia Domestica: Un modelo grupal de intervención

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    Spatiotemporal Characteristics of the Largest HIV-1 CRF02_AG Outbreak in Spain: Evidence for Onward Transmissions

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    Background and Aim: The circulating recombinant form 02_AG (CRF02_AG) is the predominant clade among the human immunodeficiency virus type-1 (HIV-1) non-Bs with a prevalence of 5.97% (95% Confidence Interval-CI: 5.41–6.57%) across Spain. Our aim was to estimate the levels of regional clustering for CRF02_AG and the spatiotemporal characteristics of the largest CRF02_AG subepidemic in Spain.Methods: We studied 396 CRF02_AG sequences obtained from HIV-1 diagnosed patients during 2000–2014 from 10 autonomous communities of Spain. Phylogenetic analysis was performed on the 391 CRF02_AG sequences along with all globally sampled CRF02_AG sequences (N = 3,302) as references. Phylodynamic and phylogeographic analysis was performed to the largest CRF02_AG monophyletic cluster by a Bayesian method in BEAST v1.8.0 and by reconstructing ancestral states using the criterion of parsimony in Mesquite v3.4, respectively.Results: The HIV-1 CRF02_AG prevalence differed across Spanish autonomous communities we sampled from (p < 0.001). Phylogenetic analysis revealed that 52.7% of the CRF02_AG sequences formed 56 monophyletic clusters, with a range of 2–79 sequences. The CRF02_AG regional dispersal differed across Spain (p = 0.003), as suggested by monophyletic clustering. For the largest monophyletic cluster (subepidemic) (N = 79), 49.4% of the clustered sequences originated from Madrid, while most sequences (51.9%) had been obtained from men having sex with men (MSM). Molecular clock analysis suggested that the origin (tMRCA) of the CRF02_AG subepidemic was in 2002 (median estimate; 95% Highest Posterior Density-HPD interval: 1999–2004). Additionally, we found significant clustering within the CRF02_AG subepidemic according to the ethnic origin.Conclusion: CRF02_AG has been introduced as a result of multiple introductions in Spain, following regional dispersal in several cases. We showed that CRF02_AG transmissions were mostly due to regional dispersal in Spain. The hot-spot for the largest CRF02_AG regional subepidemic in Spain was in Madrid associated with MSM transmission risk group. The existence of subepidemics suggest that several spillovers occurred from Madrid to other areas. CRF02_AG sequences from Hispanics were clustered in a separate subclade suggesting no linkage between the local and Hispanic subepidemics

    "La Quijotita y su prima"

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    Persigan a los masones y triunfaran los Borbones

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    Author's commentary on the continued persecution of the Freemasons. Signed 'El Pensador', dated 27 September 182

    Dia del juicio y buena loa al hipocrita Gamboa

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    José Joaquín Fernández de Lizardi's response to José Mariano Díaz Gamboa's 1825 pamphlet entitled 'Papeles y hechos impíos merecen los desafíos, o sea culebra de agua y tormenta de rayos sobre El Pensador Mexicano'. Includes several poetic verses and a 'Soneto'. Dated 5 July 182

    Respuesta del Pensador a Anita la Tamalera

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    José Joaquín Fernández de Lizardi's response to 'Anita la Tamalera ha dado en ser diputada. Carta primera al Pensador Mexicano', discussing the role of prominent women alongside men, the church and society, and elections. See also 1570/1874.(8/15.

    Niveles de estrés y patrones de adaptación de mujeres diagnosticadas con cáncer de mama del área metropolitana de San Juan, a mayo de 1998

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    Guerra de religion anunciada por el R. obispo y cabildo de Oajaca, En la contestacion que dieron al dictámen de las comisiones sobre las instrucciones al enviado á Roma

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    Author's commentary on the publication 'Contestacion del obispo y cabildo de Oajaca al oficio del exmo. señor ministro de justicia y negocios eclesiásticos, fecha 29 de marzo de 826, con que á nombre del exmo. señor presidente de la federacion les remitió el dictamen de los señores de las comisiones unidas de relaciones y eclesiástica de 28 de febrero del mismo año, sobre instrucciones al enviado á Roma cerca de S. S. la suprema cabeza de la iglesia'. Signed 'El Pensador

    Segunda defensa de los Fracmasones. Por el Pensador Mejicano

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    Author's response to critics of his pamphlet 'Defensa de los Fracmasones por el Pensador Mexicano', which contains critical observations on the papal bulls of Clement XII (28 April 1738) and Benedict XIV (18 May 1751), and addresses issues including freemasonry and censorship, and his clarification of his intentions and purposes for writing this article. Includes the full text of 'Defensa de los Fracmasones por el Pensador Mexicano'. See also 1570/1874.(3/10.

    Por la salud de la patria se desprecia una corona

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    Commentary of the consequences of having a monarchy or an emperor on the well-being of the citizens of South America. Signed 'El Pensador', dated 7 March 182
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