7 research outputs found

    Measuring Retiming Responses of Passengers to a Prepeak Discount Fare by Tracing Smart Card Data: A Practical Experiment in the Beijing Subway

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    Understanding passengers’ responses to fare changes is the basis to design reasonable price policies. This work aims to explore retiming responses of travelers changing departure times due to a prepeak discount pricing strategy in the Beijing subway in China, using smart card records from an automatic fare collection (AFC) system. First, a new set of classification indicators is established to segment passengers through a two-step clustering approach. Then, the potentially influenced passengers for the fare policy are identified, and the shifted passengers who changed their departure time are detected by tracing changes in passengers’ expected departure times before and after the policy. Lastly, the fare elasticity of departure time is defined to measure the retiming responses of passengers. Two scenarios are studied of one month (short term) and six months (middle term) after the policy. The retiming elasticity of different passenger groups, retiming elasticity over time, and retiming elasticity functions of shifted time are measured. The results show that there are considerable differences in the retiming elasticities of different passenger groups; low-frequency passengers are more sensitive to discount fares than high-frequency passengers. The retiming elasticity decreases greatly with increasing shifted time, and 30 minutes is almost the maximum acceptable shifted time for passengers. Moreover, the retiming elasticity of passengers in the middle term is approximately twice that in the short term. Applications of fare optimization are also executed, and the results suggest that optimizing the valid time window of the discount fares is a feasible way to improve the congestion relief effect of the policy, while policy makers should be cautious to change fare structures and increase discounts. Document type: Articl

    Managing Recurrent Congestion of Subway Network in Peak Hours with Station Inflow Control

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    Station inflow control (SIC) is an important and effective method for reducing recurrent congestion during peak hours in the Beijing, Shanghai, and Guangzhou subway systems. This work proposes a practical and efficient method for establishing a static SIC scheme in normal weekdays for large-scale subway networks. First, a traffic assignment model without capacity constraint is utilized to determine passenger flow distributions on the network. An internal relationship between station inflows and section flows is then constructed. Second, capacity bottlenecks are identified by considering the transport capacity of each section. Then, a feedback-based bottleneck elimination strategy is established to search target control stations and determine their control time and control strength. To validate the effectiveness of the proposed approach, a decision support system coded in the C# programming language was developed, and the Beijing subway was used as a case study. The results indicate that the proposed method and tool are capable of practical applications, and the generated SIC plan has better performance over the existing SIC plan. This study provides a practical and useful method for operation agencies to construct SIC schemes in the subway system

    Effects of short-chain fatty acids in inhibiting HDAC and activating p38 MAPK are critical for promoting B10 cell generation and function

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    Abstract B10 cells are regulatory B cells capable of producing IL-10 for maintaining immune homeostasis. Dysregulation of B10 cells occurs in autoimmune and inflammatory diseases. Modulation or adoptive transfer of B10 cells is a promising therapeutic strategy. The short-chain fatty acids (SCFAs), the metabolites of microbiota, play a critical role in maintaining immune homeostasis and are the potential drugs for the modulation of B10 cells. It is not clear whether and how SCFAs upregulate the frequency of B10 cells. Here, we found that SCFAs could promote murine and human B10 cell generation in vitro. Upregulation of B10 cells by butyrate or pentanoate was also observed in either healthy mice, mice with dextran sodium sulfate (DSS)-induced colitis, or mice with collagen-induced arthritis. Moreover, SCFA treatment could ameliorate clinical scores of colitis and arthritis. Adoptive transfer of B cells pretreated with butyrate showed more alleviation of DSS-induced colitis than those without butyrate. A further study demonstrates that SCFAs upregulate B10 cells in a manner dependent on their histone deacetylase (HDAC) inhibitory activity and independent of the G-protein-coupled receptor pathway. Transcriptomic analysis indicated that the MAPK signaling pathway was enriched in B10 cells treated with butyrate. A study with inhibitors of ERK, JNK, and p38 MAPK demonstrated that activating p38 MAPK by butyrate is critical for the upregulation of B10 cells. Moreover, HDAC inhibitor has similar effects on B10 cells. Our study sheds light on the mechanism underlying B10 cell differentiation and function and provides a potential therapeutic strategy with SCFAs and HDAC inhibitors for inflammation and autoimmune diseases

    Enhanced Photoluminescence and Electrical Properties of n-Al-Doped ZnO Nanorods/p-B-Doped Diamond Heterojunction

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    The hydrothermal approach has been used to fabricate a heterojunction of n-aluminum-doped ZnO nanorods/p-B-doped diamond (n-Al:ZnO NRs/p-BDD). It exhibits a significant increase in photoluminescence (PL) intensity and a blue shift of the UV emission peak when compared to the n-ZnO NRs/p-BDD heterojunction. The current voltage (I-V) characteristics exhibit excellent rectifying behavior with a high rectification ratio of 838 at 5 V. The n-Al:ZnO NRs/p-BDD heterojunction shows a minimum turn-on voltage (0.27 V) and reverse leakage current (0.077 μA). The forward current of the n-Al:ZnO NRs/p-BDD heterojunction is more than 1300 times than that of the n-ZnO NRs/p-BDD heterojunction at 5 V. The ideality factor and the barrier height of the Al-doped device were found to decrease. The electrical transport behavior and carrier injection process of the n-Al:ZnO NRs/p-BDD heterojunction were analyzed through the equilibrium energy band diagrams and semiconductor theoretical models

    Photoluminescence and Electrical Properties of n-Ce-Doped ZnO Nanoleaf/p-Diamond Heterojunction

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    The n-type Ce:ZnO (NL) grown using a hydrothermal method was deposited on a p-type boron-doped nanoleaf diamond (BDD) film to fabricate an n-Ce:ZnO NL/p-BDD heterojunction. It shows a significant enhancement in photoluminescence (PL) intensity and a more pronounced blue shift of the UV emission peak (from 385 nm to 365 nm) compared with the undoped heterojunction (n-ZnO/p-BDD). The prepared heterojunction devices demonstrate good thermal stability and excellent rectification characteristics at different temperatures. As the temperature increases, the turn-on voltage and ideal factor (n) of the device gradually decrease. The electronic transport behaviors depending on temperature of the heterojunction at different bias voltages are discussed using an equilibrium band diagram and semiconductor theoretical model
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