Antibiotic delivery in treating acute purulent pyelonephritis in experimental animals

The article presents the results of treatment of acute purulent pyelonephritis simulated method of transport antibiotics. The aim of this work: an experimental rationale for the effectiveness of directed transport of antibiotics in acute purulent pyelonephritis in animals. The article presents a study of antibiotic concentrations in plasma and kidney tissues under different methods of antibiotics. The author gives morphological rationale for the use of techniques aimed at transport antibiotics modeled acute purulent pyelonephritis. The study found that when introducing cefotaxim method of transport of its concentration in renal tissue above and in the blood plasma of more constant than the traditional intravenous antibiotics. Implementation of the antibacterial therapy method of transport in the treatment of acute purulent pyelonephritis contributes to an earlier normalization of peripheral blood and accelerated the rate of reparative processes.В статье приводятся результаты лечения моделированного острого гнойного пиелонефрита методом направленного транспорта антибиотиков. Цель работы: экспериментальное обоснование эффективности направленного транспорта антибиотиков при остром гнойном пиелонефрите у животных. В статье представлены исследования концентрации антибиотика в плазме крови и ткани почки при различных методах введения антибиотиков. Авторы приводят морфологическое обоснование применения методики направленного транспорта антибиотиков при моделированном остром гнойном пиелонефрите. В ходе исследования было установлено, что при введении цефотаксима методом направленного транспорта его концентрация в почечной ткани выше, чем при традиционном внутривенном введении антибиотика, а в плазме крови более постоянна. Проведение антибактериальной терапии методом направленного транспорта в лечении острого гнойного пиелонефрита способствует более ранней нормализации показателей периферической крови и ускорению темпов репаративных процессов

Ypsolopha admirandella sp. n. (Lepidoptera: Ypsolophidae), a new European species from the steppes of Russia

Sachkov, Sergey A., Zolotuhin, Vadim V. (2020): Ypsolopha admirandella sp. n. (Lepidoptera: Ypsolophidae), a new European species from the steppes of Russia. Zootaxa 4822 (4): 588-594, DOI: https://doi.org/10.11646/zootaxa.4822.4.

A new species of Meharia Chretien, 1915 (Cossidae) from the Lower Volga Region

Volume: 28Start Page: 49End Page: 5

A new species of Typhonoya Prozorov (Lepidoptera, Lasiocampidae, Lasiocampinae, Gastropachini) from the moist broadleaf forest of the Democratic Republic of the Congo

The second species of the genus Typhonoya Prozorov 2011T. kravchenkoi Prozorov, Mller Zolotuhin sp. n. from the Democratic Republic of the Congo is described. A previously monotypic genus becomes bitypic. One paratype specimen was collected in the buffer zone of the southern part of the Salonga National Park during a one year-long stationary expedition (June 2017June 2018). Spread imagoes, heads, legs, venations and genitalia of both species are figured and compared. Additional notes on the genus description and previously known species are adde

Properties and Hydrolysis Behavior of Celluloses of Different Origin

The present paper is a fundamental study on the physicochemical properties and hydrolysis behavior of cellulose samples differing in origin: bacterial, synthetic, and vegetal. Bacterial cellulose was produced by Medusomyces gisevii Sa-12 in an enzymatic hydrolyzate derived from oat-hull pulp. Synthetic cellulose was obtained from an aqueous glucose solution by electropolymerization. Plant-based cellulose was isolated by treatment of Miscanthus sacchariflorus with dilute NaOH and HNO3 solutions. We explored different properties of cellulose samples, such as chemical composition, degree of polymerization (DP), degree of crystallinity (DC), porosity, and reported infrared spectroscopy and scanning electron microscopy results. The hydrolysis behavior was most notable dependent on the origin of cellulose. For the bacterial cellulose sample (2010 DP, 90% DC, 89.4% RS yield), the major property affecting the hydrolysis behavior was its unique nanoscale reticulate structure promoting fast penetration of cellulases into the substrate structure. The study on enzymatic hydrolysis showed that the hydrolysis behavior of synthetic and Miscanthus celluloses was most influenced by the substrate properties such as DP, DC and morphological structure. The yield of reducing sugars (RS) by hydrolysis of synthetic cellulose exhibiting a 3140 DP, 80% DC, and highly depolymerization-resistant fibers was 27%. In contrast, the hydrolysis of Miscanthus-derived cellulose with a 1030 DP, 68% DC, and enzyme-accessible fibers provided the highest RS yield of 90%. The other properties examined herein (absence/presence of non-cellulosic impurities, specific surface, pore volume) had no considerable effect on the bioconversion of the cellulosic substrates