64 research outputs found

    Long-term outcome after inflammatory abdominal aortic aneurysm repair: case-matched study

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    The purpose of this study was to compare early and late outcomes after inflammatory and noninflammatory abdominal aortic aneurysm (AAA) repair with emphasis on graft-related complications. Of 625 consecutive patients submitted to AAA repair, 18 were classified as having inflammatory AAAs (group 1). The results of this group were compared with those of 54 patients (group 2) retrospectively drawn from patients who underwent aortic replacement for noninflammatory AAAs. A computer-assisted matching system was used to match patients according to date of birth, gender, and surgical priority. All patients of both groups were followed by periodic clinical and instrumental examinations. Patients in group 1 complained more frequently of aneurysm-related symptoms (72% vs. 20%; p = 0.0001), and their erythrocyte sedimentation rate was elevated more often (78% vs. 19%; p < 0.0001). Surgical morbidity and mortality rates were not different. The mean lengths of follow-up were 61 +/- 47 months (group 1) and 71 +/- 38 months (group 2). The 10-year overall survival rates did not differ significantly between the two groups (49.1% +/- 16.9% for group 1 vs. 61.6% +/- 13.8% for group 2; p = 0.26, log-rank test). In contrast, the free from paraanastomotic aneurysm survival rates were significantly lower in group 1 (57.3% +/- 20.2% vs. 97.8% +/- 2.5% at 10 years; p = 0.025, log-rank test). Long-term outcomes showed a higher incidence of graft-related complications in group 1. As inflammatory aneurysms might represent a risk factor for the development of paraanastomotic aneurysms, routine imaging surveillance of graft aortic healing after inflammatory AAA repair is warranted

    Lentiviral Gene Therapy for p47(phox) Deficient Chronic Granulomatous Disease

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    A distinct bacterial dysbiosis associated skin inflammation in ovine footrot

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    Ovine footrot is a highly prevalent bacterial disease caused by Dichelobacter nodosus and characterised by the separation of the hoof horn from the underlying skin. The role of innate immune molecules and other bacterial communities in the development of footrot lesions remains unclear. This study shows a significant association between the high expression of IL1β and high D. nodosus load in footrot samples. Investigation of the microbial population identified distinct bacterial populations in the different disease stages and also depending on the level of inflammation. Treponema (34%), Mycoplasma (29%) and Porphyromonas (15%) were the most abundant genera associated with high levels of inflammation in footrot. In contrast, Acinetobacter (25%), Corynebacteria (17%) and Flavobacterium (17%) were the most abundant genera associated with high levels of inflammation in healthy feet. This demonstrates for the first time there is a distinct microbial community associated with footrot and high cytokine expression

    Field-study science classrooms as positive and enjoyable learning environments

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    We investigated differences between field-study classrooms and traditional science classrooms in terms of the learning environment and students’ attitudes to science, as well as the differential effectiveness of field-study classrooms for students differing in sex and English proficiency. A modified version of selected scales from the What Is Happening In this Class? questionnaire was used to assess the learning environment, whereas students’ attitudes were assessed with a shortened version of a scale from the Test of Science Related Attitudes. A sample of 765 grade 5 students from 17 schools responded to the learning environment and attitude scales in terms of both their traditional science classrooms and classrooms at a field-study centre in Florida. Large effect sizes supported the effectiveness of the field-studies classroom in terms of both the learning environment and student attitudes. Relative to the home school science class, the field-study class was considerably more effective for students with limited English proficiency than for native English speakers

    Region-oriented compression of multispectral images by shape-adaptive wavelet transform and spiht

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    We present a new technique for the compression of remote-sensing hyperspectral images based on wavelet transform and zerotree coding of coefficients. In order to improve encoding efficiency, the image is first segmented in a small number of regions with homogeneous texture. Then, a shape-adaptive wavelet transform is carried out on each region, and the resulting coefficients are finally encoded by a shape-adaptive version of SPIHT. Thanks to the segmentation map (sent as a side information) region boundaries are faithfully preserved, and selective encoding strategies can be easily implemented. In addition, by-now homogeneous region textures can be more efficiently encoded. © 2004 IEEE

    Trading off quality and complexity for a HVQ-based video codec on portable devices

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    Bandwidth and processing requirements of multimedia applications typically exceed capabilities of portable terminals with current technology. Applications should hence be able to accommodate their requirements to run on these devices. In this paper, we provide a performance characterization of a video codec based on techniques such as hierarchical vector quantization which trade off complexity and reproduction quality. Comparison with standard codecs shows a remarkable reduction of coding times, such that real-time coding/decoding of video becomes possible even on low-power devices. This complexity reduction is counterbalanced by reproduction quality impairment. Nevertheless, for application such as video-conference, subjective quality seems to be fairly acceptable. Our analysis also quantifies some limitations of low-power devices with current technology. © 2005 Elsevier Inc. All rights reserved
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