116 research outputs found
Deep learning-based denoising streamed from mobile phones improves speech-in-noise understanding for hearing aid users
The hearing loss of almost half a billion people is commonly treated with
hearing aids. However, current hearing aids often do not work well in
real-world noisy environments. We present a deep learning based denoising
system that runs in real time on iPhone 7 and Samsung Galaxy S10 (25ms
algorithmic latency). The denoised audio is streamed to the hearing aid,
resulting in a total delay of around 75ms. In tests with hearing aid users
having moderate to severe hearing loss, our denoising system improves audio
across three tests: 1) listening for subjective audio ratings, 2) listening for
objective speech intelligibility, and 3) live conversations in a noisy
environment for subjective ratings. Subjective ratings increase by more than
40%, for both the listening test and the live conversation compared to a fitted
hearing aid as a baseline. Speech reception thresholds, measuring speech
understanding in noise, improve by 1.6 dB SRT. Ours is the first denoising
system that is implemented on a mobile device, streamed directly to users'
hearing aids using only a single channel as audio input while improving user
satisfaction on all tested aspects, including speech intelligibility. This
includes overall preference of the denoised and streamed signal over the
hearing aid, thereby accepting the higher latency for the significant
improvement in speech understanding
Solid-state bioconversion of passion fruit waste by whiterot fungi for production of oxidative and hydrolytic enzymes.
Current in coherent quantum systems connected to mesoscopic Fermi reservoirs
We study particle current in a recently proposed model for coherent quantum transport. In this model, a system connected to mesoscopic Fermi reservoirs (meso-reservoir) is driven out of equilibrium by the action of super-reservoirs thermalized to prescribed temperatures and chemical potentials by a simple dissipative mechanism described by the Lindblad equation. We compare exact (numerical) results with theoretical expectations based on the Landauer formula
LUPO - Ausbau der Suchfunktionalität der Landesumweltportale und Vernetzung mit dem Umweltportal Deutschland
FADO - Funktionale Konsolidierung des Fachdokumentenmanagements im Umweltinformationssystem Baden-Württemberg und Erschließung neuer Themenbereiche
Desensitizing treatments for dentin hypersensitivity: a randomized, split-mouth clinical trial
Morphological docking of secretory vesicles
Calcium-dependent secretion of neurotransmitters and hormones is essential for brain function and neuroendocrine-signaling. Prior to exocytosis, neurotransmitter-containing vesicles dock to the target membrane. In electron micrographs of neurons and neuroendocrine cells, like chromaffin cells many synaptic vesicles (SVs) and large dense-core vesicles (LDCVs) are docked. For many years the molecular identity of the morphologically docked state was unknown. Recently, we resolved the minimal docking machinery in adrenal medullary chromaffin cells using embryonic mouse model systems together with electron-microscopic analyses and also found that docking is controlled by the sub-membrane filamentous (F-)actin. Currently it is unclear if the same docking machinery operates in synapses. Here, I will review our docking assay that led to the identification of the LDCV docking machinery in chromaffin cells and also discuss whether identical docking proteins are required for SV docking in synapses
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