Extending the concept of the morphological frame: a case study of Tangshan old military airport

[EN] The concept of the morphological frame is important in urban morphology, but it has been discussed much less than other critical concepts, such as the fringe belt and the fixation line. Passing its features on as inherited outlines, the morphological frame contains not only the linear fixation line, but also ground plan and three-dimensional aspects. In this research, the linear, ground plan, and three-dimensional morphological frame of Tangshan old military airport during the expansion of the city after the removal of the airport is identified. The former boundary roads of the airport exert obvious influences on the division of plots. The former arterial roads also function as a linear morphological frame. In relation to the ground plan, property rights and plots containing important buildings have an impact on the consequent town plan. The distinct feature of the morphological frame of the airport is its three-dimensional constraint, i.e. the vertical clearance requirement, which restricted the height of surrounding buildings. The impact of this institutional limit can last a very long time owing to the high cost of demolishing the old surrounding buildings or adding extra storeys even if the limit ceased to exist with the removal of the airport. Based on this case study, this paper refines and extends the connotation of the concept of the morphological frame and further discusses the relationship between function and form.Peng, R.; Zhang, Z.; Li, Y.; Song, F. (2018). Extending the concept of the morphological frame: a case study of Tangshan old military airport. En 24th ISUF International Conference. Book of Papers. Editorial Universitat Politècnica de València. 265-272. https://doi.org/10.4995/ISUF2017.2017.5686OCS26527

Design of Wideband High-Gain Patch Antenna Array for High-Temperature Applications

A low-profile, wideband, and high-gain antenna array, based on a novel double-H-shaped slot microstrip patch radiating element and robust against high temperature variations, is proposed in this work. The antenna element was designed to operate in the frequency range between 12 GHz and 18.25 GHz, with a 41.3% fractional bandwidth (FBW) and an obtained peak gain equal to 10.2 dBi. The planar array, characterized by a feed network with a flexible 1 to 16 power divider, comprised 4 × 4 antenna elements and generated a pattern with a peak gain of 19.1 dBi at 15.5 GHz. An antenna array prototype was fabricated, and the measurements showed good agreement with the numerical simulations as the manufactured antenna operated in the range of 11.4–17 GHz, with a 39.4% FBW, and the peak gain at 15.5 GHz was 18.7 dBi. The high-temperature simulated and experimental results, performed in a temperature chamber, demonstrated that the array performance was stable in a wide temperature range, from −50 °C to 150 °C

Rapid Detection of A282S Mutation in the <i>RDL1</i> Gene of Rice Stem Borer via the Mutation-Specific LAMP Technique

Rice stem borer Chilo suppressalis (Walker) is one of the most serious pests on rice and is distributed worldwide. With the long-term and continuous usage of insecticides, C. suppressalis has developed high levels of resistance to various kinds of insecticides, including phenylpyrazole insecticides. As is well known, the resistance of C. suppressalis to phenylpyrazole insecticides is determined by the A282S mutation of the GABA receptor RDL subunit. In order to efficiently detect the resistance of C. suppressalis, a rapid and sensitive loop-mediated isothermal amplification (LAMP) technique was established and optimized in this study. The optimal concentration of components was Bst DNA polymerase (0.24 U/μL), dNTP (0.8 mM), Mg2+ (4 mM), betaine (0.6 M), forward inner primer and backward inner primer (1.6 μM), F3 and B3 (0.4 μM), and hydroxyl naphthol blue (150 mM), respectively, and the optimal reaction condition was 63 °C for 60 min, which could reduce the cost and time of detection. In addition, the accuracy of the optimized LAMP reaction system and parameters was verified in the field strains of C. suppressalis from different regions, including Jiangsu, Jiangxi, and Hu’nan provinces. The mutation (A2’S) was successfully detected in the field strains. As far as we know, this is the first report of the LAMP technique applied in the resistance monitoring of C. suppressalis to phenylpyrazole insecticides. According to our results, the optimized LAMP reaction system is feasible and easy to operate and to efficiently detect resistance-related mutation in a short time, as directly judged by the naked eye. Our results provide a new tool for detection of resistance of C. suppressalis, which is a very useful tool for comprehensive management of C. suppressalis

Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke

Abstract Background Atrial fibrillation (AF) is one of the most prevalent sustained arrhythmias, however, epidemiological data may understate its actual prevalence. Meanwhile, AF is considered to be a major cause of ischemic strokes due to irregular heart-rhythm, coexisting chronic vascular inflammation, and renal insufficiency, and blood stasis. We studied co-expressed genes to understand relationships between atrial fibrillation (AF) and stroke and reveal potential biomarkers and therapeutic targets of AF-related stroke. Methods AF-and stroke-related differentially expressed genes (DEGs) were identified via bioinformatic analysis Gene Expression Omnibus (GEO) datasets GSE79768 and GSE58294, respectively. Subsequently, extensive target prediction and network analyses methods were used to assess protein–protein interaction (PPI) networks, Gene Ontology (GO) terms and pathway enrichment for DEGs, and co-expressed DEGs coupled with corresponding predicted miRNAs involved in AF and stroke were assessed as well. Results We identified 489, 265, 518, and 592 DEGs in left atrial specimens and cardioembolic stroke blood samples at < 3, 5, and 24 h, respectively. LRRK2, CALM1, CXCR4, TLR4, CTNNB1, and CXCR2 may be implicated in AF and the hub-genes of CD19, FGF9, SOX9, GNGT1, and NOG may be associated with stroke. Finally, co-expressed DEGs of ZNF566, PDZK1IP1, ZFHX3, and PITX2 coupled with corresponding predicted miRNAs, especially miR-27a-3p, miR-27b-3p, and miR-494-3p may be significantly associated with AF-related stroke. Conclusion AF and stroke are related and ZNF566, PDZK1IP1, ZFHX3, and PITX2 genes are significantly associated with novel biomarkers involved in AF-related stroke