117 research outputs found
High-purity recycling of hematite and Zn/Cu mixture from waste smelting slag
In this study, Zn/Cu-bearing smelting slag was recycled via an integrated acid dissolution and hematite precipitation method. The slag was dissolved in nitric acid to generate an acid solution containing 23.5 g/L Fe, 4.45 g/L Zn and 2.81 g/L Cu, which was subjected to hydrothermal treatment with the addition of levulinic acid (LA). More than 99.95% of the initial Fe content was removed as hematite particles with diameters of approximately 200 nm, and the residual Fe concentration in the acid was 0.43 mg/L. The generated hematite contained 97.3% Fe2O3, 0.64% ZnO and 0.58% CuO. Greater than 99% of the initial Zn and Cu was retained in the acid and further precipitated as Zn/Cu-bearing solids by adjusting the solution pH to 9. The precipitated Zn/Cu-bearing solids contained 33.6% Zn and 21.7% Cu, whereas the Fe content was less than 0.2%. This paper is the first report of an environmentally friendly approach for recycling smelting slag without generating any hazardous waste
Ultra-Strong Long-Chain Polyamide Elastomers With Programmable Supramolecular Interactions and Oriented Crystalline Microstructures
Polyamides are one of the most important polymers. Long-chain aliphatic polyamides could bridge the gap between traditional polyamides and polyethylenes. Here we report an approach to preparing sustainable ultra-strong elastomers from biomass-derived long-chain polyamides by thiol-ene addition copolymerization with diamide diene monomers. The pendant polar hydroxyl and non-polar butyrate groups between amides allow controlled programming of supramolecular hydrogen bonding and facile tuning of crystallization of polymer chains. The presence of thioether groups on the main chain can further induce metal–ligand coordination (cuprous-thioether). Unidirectional step-cycle tensile deformation has been applied to these polyamides and significantly enhances tensile strength to over 210 MPa while maintaining elasticity. Uniaxial deformation leads to a rearrangement and alignment of crystalline microstructures, which is responsible for the mechanical enhancement. These chromophore-free polyamides are observed with strong luminescence ascribed to the effect of aggregation-induced emission (AIE), originating from the formation of amide clusters with restricted molecular motions
The effect of peak serum estradiol level during ovarian stimulation on cumulative live birth and obstetric outcomes in freeze-all cycles
ObjectiveTo determine whether the peak serum estradiol (E2) level during ovarian stimulation affects the cumulative live birth rate (CLBR) and obstetric outcomes in freeze-all cycles.MethodsThis retrospective cohort study involved patients who underwent their first cycle of in vitro fertilization followed by a freeze-all strategy and frozen embryo transfer cycles between January 2014 and June 2019 at a tertiary care center. Patients were categorized into four groups according to quartiles of peak serum E2 levels during ovarian stimulation (Q1-Q4). The primary outcome was CLBR. Secondary outcomes included obstetric and neonatal outcomes of singleton and twin pregnancies. Poisson or logistic regression was applied to control for potential confounders for outcome measures, as appropriate. Generalized estimating equations were used to account for multiple cycles from the same patient for the outcome of CLBR.Result(s)A total of 11237 patients were included in the analysis. Cumulatively, live births occurred in 8410 women (74.8%). The live birth rate (LBR) and CLBR improved as quartiles of peak E2 levels increased (49.7%, 52.1%, 54.9%, and 56.4% for LBR; 65.1%, 74.3%, 78.4%, and 81.6% for CLBR, from the lowest to the highest quartile of estradiol levels, respectively, P<0.001). Such association remained significant for CLBR after accounting for potential confounders in multivariable regression models, whereas the relationship between LBR and peak E2 levels did not reach statistical significance. In addition, no significant differences were noticed in adverse obstetric and neonatal outcomes (gestational diabetes mellitus, pregnancy-induced hypertension, preeclampsia, placental disorders, preterm birth, low birthweight, and small for gestational age) amongst E2 quartiles for either singleton or twin live births, both before and after adjustment.ConclusionIn freeze-all cycles, higher peak serum E2 levels during ovarian stimulation were associated with increased CLBR, without increasing the risks of adverse obstetric and neonatal outcomes
Nonalcoholic Fatty Liver Disease and Associated Metabolic Risks of Hypertension in Type 2 Diabetes: A Cross-Sectional Community-Based Study
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Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by next-generation sequencing with linkage analyses
In vitro fertilization (IVF), preimplantation genetic diagnosis (PGD), and preimplantation genetic screening (PGS) help patients to select embryos free of monogenic diseases and aneuploidy (chromosome abnormality). Next-generation sequencing (NGS) methods, while experiencing a rapid cost reduction, have improved the precision of PGD/PGS. However, the precision of PGD has been limited by the false-positive and false-negative single-nucleotide variations (SNVs), which are not acceptable in IVF and can be circumvented by linkage analyses, such as short tandem repeats or karyomapping. It is noteworthy that existing methods of detecting SNV/copy number variation (CNV) and linkage analysis often require separate procedures for the same embryo. Here we report an NGS-based PGD/PGS procedure that can simultaneously detect a single-gene disorder and aneuploidy and is capable of linkage analysis in a cost-effective way. This method, called "mutated allele revealed by sequencing with aneuploidy and linkage analyses" (MARSALA), involves multiple annealing and looping-based amplification cycles (MALBAC) for single-cell whole-genome amplification. Aneuploidy is determined by CNVs, whereas SNVs associated with the monogenic diseases are detected by PCR amplification of the MALBAC product. The false-positive and -negative SNVs are avoided by an NGS-based linkage analysis. Two healthy babies, free of the monogenic diseases of their parents, were born after such embryo selection. The monogenic diseases originated from a single base mutation on the autosome and the X-chromosome of the disease-carrying father and mother, respectively.Chemistry and Chemical Biolog
The Simons Observatory: Magnetic Sensitivity Measurements of Microwave SQUID Multiplexers
The Simons Observatory (SO) will be a cosmic microwave background (CMB)
survey experiment with three small-aperture telescopes and one large-aperture
telescope, which will observe from the Atacama Desert in Chile. In total, SO
will field 70,000 transition-edge sensor (TES) bolometers in six spectral
bands centered between 27 and 280 GHz in order to achieve the sensitivity
necessary to measure or constrain numerous cosmological quantities. The SO
Universal Focal Plane Modules (UFMs) each contain a 150 mm diameter TES
detector array, horn or lenslet optical coupling, cold readout components, and
magnetic shielding. SO will use a microwave SQUID multiplexing (MUX)
readout at an initial multiplexing factor of 1000; the cold (100 mK)
readout components are packaged in a MUX readout module, which is part of
the UFM, and can also be characterized independently. The 100 mK stage TES
bolometer arrays and microwave SQUIDs are sensitive to magnetic fields, and
their measured response will vary with the degree to which they are
magnetically shielded. We present measurements of the magnetic pickup of test
microwave SQUID multiplexers as a study of various shielding configurations for
the Simons Observatory. We discuss how these measurements motivated the
material choice and design of the UFM magnetic shielding.Comment: 5 pages, 6 figures, conference proceedings submitted to IEEE
Transactions on Applied Superconductivit
The Simons Observatory microwave SQUID multiplexing detector module design
Advances in cosmic microwave background (CMB) science depend on increasing
the number of sensitive detectors observing the sky. New instruments deploy
large arrays of superconducting transition-edge sensor (TES) bolometers tiled
densely into ever larger focal planes. High multiplexing factors reduce the
thermal loading on the cryogenic receivers and simplify their design. We
present the design of focal-plane modules with an order of magnitude higher
multiplexing factor than has previously been achieved with TES bolometers. We
focus on the novel cold readout component, which employs microwave SQUID
multiplexing (mux). Simons Observatory will use 49 modules containing
60,000 bolometers to make exquisitely sensitive measurements of the CMB. We
validate the focal-plane module design, presenting measurements of the readout
component with and without a prototype detector array of 1728
polarization-sensitive bolometers coupled to feedhorns. The readout component
achieves a yield and a 910 multiplexing factor. The median white noise
of each readout channel is 65 . This impacts the
projected SO mapping speed by , which is less than is assumed in the
sensitivity projections. The results validate the full functionality of the
module. We discuss the measured performance in the context of SO science
requirements, which are exceeded.Comment: Accepted to The Astrophysical Journa
The Simons Observatory Large Aperture Telescope Receiver
The Simons Observatory (SO) Large Aperture Telescope Receiver (LATR) will be
coupled to the Large Aperture Telescope located at an elevation of 5,200 m on
Cerro Toco in Chile. The resulting instrument will produce arcminute-resolution
millimeter-wave maps of half the sky with unprecedented precision. The LATR is
the largest cryogenic millimeter-wave camera built to date with a diameter of
2.4 m and a length of 2.6 m. It cools 1200 kg of material to 4 K and 200 kg to
100 mk, the operating temperature of the bolometric detectors with bands
centered around 27, 39, 93, 145, 225, and 280 GHz. Ultimately, the LATR will
accommodate 13 40 cm diameter optics tubes, each with three detector wafers and
a total of 62,000 detectors. The LATR design must simultaneously maintain the
optical alignment of the system, control stray light, provide cryogenic
isolation, limit thermal gradients, and minimize the time to cool the system
from room temperature to 100 mK. The interplay between these competing factors
poses unique challenges. We discuss the trade studies involved with the design,
the final optimization, the construction, and ultimate performance of the
system
A Data Driven Educational Decision Support System
To make use of the latest Internet technology to provide innovative support for teacher education, a comprehensive study is made on DDEDSS (data driven education decision support system) and DDEDSS software prototype is designed and developed as an auxiliary tool for educational decision-making. At the same time, the two sessions of education data is collected and tested in practice. The multidimensional summation and average are carried out for different time, different source regions, different gender learners and different subjects. The research results show that the system can evaluate learners' learning and further provide decision-making basis for curriculum optimization and class adjustment. It can be seen that DDEDSS is a frontier educational research, which has important research significance
Microwave synthesis of tubular zeolitic imidazolate framework ZIF-8 membranes for CO2/CH4 separation
The separation of CO2/CH4 is reported in detail by using zeolitic imidazolate framework (ZIF-8) membrane which was prepared on 3-aminopropyltriethoxysilane modified Al2O3 tube through microwave heating synthesis. Attributed to the preferential adsorption affinity of CO2 over CH4 and a narrow pore window of 0.34 nm, the ZIF-8 membrane shows high separation performances for the separation of CO2/CH4 mixtures. For the separation of equimolar CO2/CH4 mixture at 100 degrees C and 2 bar feed (1 bar permeate) pressure, a CO2 permeance of 1.02 x 10(-8) mol/m(2)center dot s center dot Pa and a CO2/CH4 selectivity of 6.8 are obtained, which is promising for CO2 separation
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