6,652 research outputs found
Linkage and mapping analyses of the no glue egg gene Ng in the silkworm (Bombyx mori L.) using simple sequence repeats (SSR) markers
In the silkworm, Bombyx mori, no glue egg is mainly controlled by Ng (No glue) gene, which is located on the 12th chromosome. Owning to a lack of crossing over in females, reciprocal backcrossed F1 (BC1) progenies were used for linkage analysis and mapping of the Ng gene based on the simple sequence repeats (SSR) linkage map using silkworm strains H9 and P50, which are Ng mutant and normal to egg, respectively. The Ng gene was found to be linked to three SSR markers. Using a reciprocal BC1M cross, we constructed a linkage map of 36.4 cM, with Ng mapped at 15.9 cM and the nearest SSR marker at a distance of 7.4 cM. Based on fine genome map of domesticated silkworm (B. mori), the result of Kaikoblast show that the physical distance between the near markers (containing Ng gene) is 181.7 Kb. Further analysis show that BGIBMGA005833, BGIBMGA005835 and BGIBMGA005836 are closer to Ng, and the BGIBMGA005835 is nearest to Ng, which physical distance is 44 Kb.Key words: Gene location, linkage analysis, microsatellite, Ng, silkworm
Interplay between elastic fields due to gravity and a partial dislocation for a hard-sphere crystal coherently grown under gravity: driving force for defect disappearance
We previously observed that an intrinsic staking fault shrunk through a glide
of a Shockley partial dislocation terminating its lower end in a hard-sphere
crystal under gravity coherently grown in by Monte Carlo simulations
[Mori et al., Molec. Phys. 105, 1377 (2007)]; it was an answer to a one-decade
long standing question why the stacking disorder in colloidal crystals reduced
under gravity [Zhu et al., Nature 387, 883 (1997)]. Here, we present an elastic
energy calculation; in addition to the self-energy of the partial dislocation
[Mori et al., Prog. Theor. Phys. Suppl. 178, 33 (2009)] we calculate the
cross-coupling term between elastic field due to gravity and that due to a
Shockley partial dislocation. The cross term is a increasing function of the
linear dimension R over which the elastic field expands, showing that a driving
force arises for the partial dislocation moving toward the upper boundary of a
grain.Comment: 8pages, 4figures, to be published in Molecular Physic
Nonlinear Impurity Modes in Homogeneous and Periodic Media
We analyze the existence and stability of nonlinear localized waves described
by the Kronig-Penney model with a nonlinear impurity. We study the properties
of such waves in a homogeneous medium, and then analyze new effects introduced
by periodicity of the medium parameters. In particular, we demonstrate the
existence of a novel type of stable nonlinear band-gap localized states, and
also reveal an important physical mechanism of the oscillatory wave
instabilities associated with the band-gap wave resonances.Comment: 11 pages, 3 figures; To be published in: Proceedings of the NATO
Advanced Research Workshop "Nonlinearity and Disorder: Theory and
Applications" (Tashkent, 2-6 Oct, 2000) Editors: P.L. Christiansen and F.K.
Abdullaev (Kluwer, 2001
Monotonicity results and bounds for the inverse hyperbolic sine
In this note, we present monotonicity results of a function involving to the
inverse hyperbolic sine. From these, we derive some inequalities for bounding
the inverse hyperbolic sine.Comment: 3 page
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Superconductivity. Quasiparticle mass enhancement approaching optimal doping in a high-T(c) superconductor.
In the quest for superconductors with higher transition temperatures (T(c)), one emerging motif is that electronic interactions favorable for superconductivity can be enhanced by fluctuations of a broken-symmetry phase. Recent experiments have suggested the existence of the requisite broken-symmetry phase in the high-T(c) cuprates, but the impact of such a phase on the ground-state electronic interactions has remained unclear. We used magnetic fields exceeding 90 tesla to access the underlying metallic state of the cuprate YBa2Cu3O(6+δ) over a wide range of doping, and observed magnetic quantum oscillations that reveal a strong enhancement of the quasiparticle effective mass toward optimal doping. This mass enhancement results from increasing electronic interactions approaching optimal doping, and suggests a quantum critical point at a hole doping of p(crit) ≈ 0.18.This work is supported by the US Department of Energy BES \Science at 100 T," the
National Science Foundation, the State of Florida, the Natural Science and Engineering
Research Council of Canada and the Canadian Institute for Advanced Research. S.E.S. ac-
knowledges support from the Royal Society and the European Research Council under the
European Union's Seventh Framework Programme (FP7/2007-2013) / ERC Grant Agree-
ment no. 337425.This is the accepted manuscript. The final version is available at http://www.sciencemag.org/content/348/6232/317.abstract?sid=a882093c-ded2-481c-b62b-2f79a56b5689
Fragile charge order in the nonsuperconducting ground state of the underdoped high-temperature superconductors.
The normal state in the hole underdoped copper oxide superconductors has proven to be a source of mystery for decades. The measurement of a small Fermi surface by quantum oscillations on suppression of superconductivity by high applied magnetic fields, together with complementary spectroscopic measurements in the hole underdoped copper oxide superconductors, point to a nodal electron pocket from charge order in YBa2Cu3(6+δ). Here, we report quantum oscillation measurements in the closely related stoichiometric material YBa2Cu4O8, which reveals similar Fermi surface properties to YBa2Cu3(6+δ), despite the nonobservation of charge order signatures in the same spectroscopic techniques, such as X-ray diffraction, that revealed signatures of charge order in YBa2Cu3(6+δ). Fermi surface reconstruction in YBa2Cu4O8 is suggested to occur from magnetic field enhancement of charge order that is rendered fragile in zero magnetic fields because of its potential unconventional nature and/or its occurrence as a subsidiary to more robust underlying electronic correlations.B.T., A.S, and S.E.S. acknowledge support from the
Royal Society, the Winton Programme for the Physics of
Sustainability, and the European Research Council under
the European Unions Seventh Framework Programme
(grant number FP/2007-2013)/ ERC Grant Agreement
number 337425. N.H., Z.Z., F.F.B., and B.J.R. acknowl-
edge support for high-magnetic-field experiments from
the US Department of Energy, Office of Science, BES-
MSE `Science of 100 Tesla' programme. G.G.L. acknowl-
edges support from EPSRC grant EP/K012894/1. Work
at NIU was supported by The Institute for Nanoscience,
Engineering, and Technology - InSET. A portion of this
work was performed at the National High Magnetic Field
Laboratory, which is supported by NSF co-operative
agreement number DMR-0654118, the state of Florida,
and the DOE. We are grateful for the experimental assis-
tance provided by National High Magnetic Field Labora-
tory personnel, including J. B. Betts, Y. Coulter, M. Gor-
don, C. H. Mielke, A. Parish, R. McDonald, D. Rickel,
and D. Roybal.This is the author accepted manuscript. The final version is available from the National Academy of Sciences via http://dx.doi.org/10.1073/pnas.150416411
A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies
A promising direction in drug development is to exploit the ability of
natural killer cells to kill antibody-labeled target cells. Monoclonal
antibodies and drugs designed to elicit this effect typically bind cell-surface
epitopes that are overexpressed on target cells but also present on other
cells. Thus it is important to understand adhesion of cells by antibodies and
similar molecules. We present an equilibrium model of such adhesion,
incorporating heterogeneity in target cell epitope density and epitope
immobility. We compare with experiments on the adhesion of Jurkat T cells to
bilayers containing the relevant natural killer cell receptor, with adhesion
mediated by the drug alefacept. We show that a model in which all target cell
epitopes are mobile and available is inconsistent with the data, suggesting
that more complex mechanisms are at work. We hypothesize that the immobile
epitope fraction may change with cell adhesion, and we find that such a model
is more consistent with the data. We also quantitatively describe the parameter
space in which binding occurs. Our results point toward mechanisms relating
epitope immobility to cell adhesion and offer insight into the activity of an
important class of drugs.Comment: 13 pages, 5 figure
Janus monolayers of transition metal dichalcogenides.
Structural symmetry-breaking plays a crucial role in determining the electronic band structures of two-dimensional materials. Tremendous efforts have been devoted to breaking the in-plane symmetry of graphene with electric fields on AB-stacked bilayers or stacked van der Waals heterostructures. In contrast, transition metal dichalcogenide monolayers are semiconductors with intrinsic in-plane asymmetry, leading to direct electronic bandgaps, distinctive optical properties and great potential in optoelectronics. Apart from their in-plane inversion asymmetry, an additional degree of freedom allowing spin manipulation can be induced by breaking the out-of-plane mirror symmetry with external electric fields or, as theoretically proposed, with an asymmetric out-of-plane structural configuration. Here, we report a synthetic strategy to grow Janus monolayers of transition metal dichalcogenides breaking the out-of-plane structural symmetry. In particular, based on a MoS2 monolayer, we fully replace the top-layer S with Se atoms. We confirm the Janus structure of MoSSe directly by means of scanning transmission electron microscopy and energy-dependent X-ray photoelectron spectroscopy, and prove the existence of vertical dipoles by second harmonic generation and piezoresponse force microscopy measurements
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