59,262 research outputs found

    Quakes in Solid Quark Stars

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    A starquake mechanism for pulsar glitches is developed in the solid quark star model. It is found that the general glitch natures (i.e., the glitch amplitudes and the time intervals) could be reproduced if solid quark matter, with high baryon density but low temperature, has properties of shear modulus \mu = 10^{30~34} erg/cm^3 and critical stress \sigma_c = 10^{18~24} erg/cm^3. The post-glitch behavior may represent a kind of damped oscillations.Comment: 11 pages, 4 figures (but Fig.3 is lost), a complete version can be obtained by http://vega.bac.pku.edu.cn/~rxxu/publications/index_P.htm, a new version to be published on Astroparticle Physic

    Creep motion of a domain wall in the two-dimensional random-field Ising model with a driving field

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    With Monte Carlo simulations, we study the creep motion of a domain wall in the two-dimensional random-field Ising model with a driving field. We observe the nonlinear fieldvelocity relation, and determine the creep exponent {\mu}. To further investigate the universality class of the creep motion, we also measure the roughness exponent {\zeta} and energy barrier exponent {\psi} from the zero-field relaxation process. We find that all the exponents depend on the strength of disorder.Comment: 5 pages, 4 figure

    Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters.

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    Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and analyses of interactions of key circadian proteins with each other and with clock gene promoters. We show that transcriptional activators control BRD4-PTEFb recruitment to E-box-containing circadian promoters. During the activating phase of the circadian cycle, the lysine acetyltransferase TIP60 acetylates the transcriptional activator BMAL1 leading to recruitment of BRD4 and the pause release factor P-TEFb, followed by productive elongation of circadian transcripts. We propose that the control of BRD4-P-TEFb recruitment is a novel temporal checkpoint in the circadian clock cycle

    Frontiers of parasitology research in the People's Republic of China : infection, diagnosis, protection and surveillance

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    ABSTRACT: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling, monitoring, evaluation, surveillance and public health response. A comprehensive effort, involving the collaboration of 188 scientists (<85% from P.R. China) from 48 different institutions and universities (80% from P.R. China), covers this collection of 29 articles published in Parasites & Vectors. The research mainly stems from a research project entitled 'Surveillance and diagnostic tools for major parasitic diseases in P.R. China' (grant no. 2008ZX10004-011) and highlights the frontiers of research in parasitology. The majority of articles in this thematic series deals with the most important parasitic diseases in P.R. China, emphasizing Schistosoma japonicum, Plasmodium vivax and Clonorchis sinensis plus some parasites of emerging importance such as Angiostrongylus cantonensis. Significant achievements have been made through the collaborative research programme in the following three fields: (i) development of control strategies for the national control programme; (ii) updating the surveillance data of parasitic infections both in human and animals; and (iii) improvement of existing, and development of novel, diagnostic tools to detect parasitic infections. The progress is considerable and warrants broad validation efforts. Combined with the development of improved tools for diagnosis and surveillance, integrated and multi-pronged control strategies now pave the way for elimination of parasitic diseases in P.R. China. Experiences and lessons learned can stimulate control and elimination efforts of parasitic diseases in other parts of the world

    On the IMF in a Triggered Star Formation Context

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    The origin of the stellar initial mass function (IMF) is a fundamental issue in the theory of star formation. It is generally fit with a composite power law. Some clues on the progenitors can be found in dense starless cores that have a core mass function (CMF) with a similar shape. In the low-mass end, these mass functions increase with mass, albeit the sample may be somewhat incomplete; in the high-mass end, the mass functions decrease with mass. There is an offset in the turn-over mass between the two mass distributions. The stellar mass for the IMF peak is lower than the corresponding core mass for the CMF peak in the Pipe Nebula by about a factor of three. Smaller offsets are found between the IMF and the CMFs in other nebulae. We suggest that the offset is likely induced during a starburst episode of global star formation which is triggered by the formation of a few O/B stars in the multi-phase media, which naturally emerged through the onset of thermal instability in the cloud-core formation process. We consider the scenario that the ignition of a few massive stars photoionizes the warm medium between the cores, increases the external pressure, reduces their Bonnor?Ebert mass, and triggers the collapse of some previously stable cores. We quantitatively reproduce the IMF in the low-mass end with the assumption of additional rotational fragmentation.Comment: 3 figure
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