Improving the matching precision of SIFT

International audienceMatching precision of scale-invariant feature transform (SIFT) is evaluated and improved in this paper. The aim of the paper is not to invent a new feature detector more invariant than the others. Instead, we focus on SIFT method and evaluate and improve the matching precision, defined as the root mean square error (RMSE) under ground truth geometric trans-form. Matching precision reflects to some extent the average relative localization precision between two images. For scale invariant feature detectors like SIFT, the matching precision decreases with the scale of features due to the sub-sampling in the scale space. We propose to cancel the sub-sampling to improve the matching precision. But in case of scale change, the improvement is marginal due to the coarse scale quanti-zation in the scale space. One more sophisticated method is also proposed to improve the matching precision in case of scale change. These modifications can be easily extended to other scale invariant feature detectors

Impact resistance of Nomex honeycomb sandwich structures with thin fibre reinforced polymer facesheets

In order to investigate the impact resistance of the Nomex honeycomb sandwich structures skinned with thin fibre reinforced woven fabric composites, both drop-weight experimental work and meso-mechanical finite element modelling were conducted and the corresponding output was compared. Drop-weight impact tests with different impact parameters, including impact energy, impactor mass and facesheets, were carried out on Nomex honeycomb-cored sandwich structures. It was found that the impact resistance and the penetration depth of the Nomex honeycomb sandwich structures were significantly influenced by the impact energy. However, for impact energies that cause full perforation, the impact resistance is characterized with almost the same initial stiffness and peak force. The impactor mass has little influence on the impact response and the perforation force is primarily dependent on the thickness of the facesheet, which generally varies linearly with it. In the numerical simulation, a comprehensive finite element model was developed which considers all the constituent materials of the Nomex honeycomb, i.e. aramid paper, phenolic resin, and the micro-structure of the honeycomb wall. The model was validated against the corresponding experimental results and then further applied to study the effects of various impact angles on the response of the honeycomb. It was found that both the impact resistance and the perforation depth are significantly influenced by the impact angle. The former increases with the obliquity, while the latter decreases with it. The orientation of the Nomex core has little effect on the impact response, while the angle between the impact direction and the fibre direction of the facesheets has a great influence on the impact response. </jats:p

Tailoring the supramolecular structure of amphiphilic glycopolypeptide analogue toward liver targeted drug delivery systems

Amphiphilic glycopolypeptide analogues have harboured great importance in the development of targeted drug delivery systems. In this study, lactosylated pullulan-graft-arginine dendrons (LP-g-G3P) was synthesized using Huisgen azide-alkyne 1,3-dipolar cycloaddition between lactosylated pullulan and generation 3 arginine dendrons bearing Pbf and Boc groups on the periphery. Hydrophilic lactosylated pullulan was selected for amphiphilic modification, aiming at specific lectin recognition. Macromolecular structure of LP-g-G3P combined alkyl, aromatic, and peptide dendritic hydrophobic moieties and was able to self-assemble spontaneously into core-shell nanoarchitectures with small particle sizes and low polydispersity in the aqueous media, which was confirmed by CAC, DLS and TEM. Furthermore, the polyaromatic anticancer drug (doxorubicin, DOX) was selectively encapsulated in the hydrophobic core through multiple interactions with the dendrons, including π-π interactions, hydrogen bonding and hydrophobic interactions. Such multiple interactions had the merits of enhanced drug loading capacity (16.89 ± 2.41%), good stability against dilution, and excellent sustained release property. The cell viability assay presented that LP-g-G3P nanoparticles had an excellent biocompatibility both in the normal and tumor cells. Moreover, LP-g-G3P/DOX nanoparticles could be effectively internalized into the hepatoma carcinoma cells and dramatically inhibited cell proliferation. Thus, this approach paves the way to develop amphiphilic and biofunctional glycopolypeptide-based drug delivery systems.the European Commission Research and Innovation (PIRSES-GA-2011-295218

Synthesis of electroneutralized amphiphilic copolymers with peptide dendrons for intramuscular gene delivery

Intramuscular gene delivery materials are of great importance in plasmid-based gene therapy system, but there is limited information so far on how to design and synthesize them. A previous study showed that the peptide dendron-based triblock copolymer with its components arranged in a reversed biomembrane architecture could significantly increase intramuscular gene delivery and expression. Herein, we wonder whether copolymers with biomembrane-mimicking arrangement may have similar function on intramuscular gene delivery. Meanwhile, it is of great significance to uncover the influence of electric charge and molecular structure on the function of the copolymers. To address the issues, amphiphilic triblock copolymers arranged in hydrophilic-hydrophobic-hydrophilic structure were constructed despite the paradoxical characteristics and difficulties in synthesizing such hydrophilic but electroneutral molecules. The as-prepared two copolymers, dendronG2(l-lysine-OH)-poly propylene glycol2k(PPG2k)-dendronG2(l-lysine-OH) (rL2PL2) and dendronG3(l-lysine-OH)-PPG2k-dendronG3(l-lysine-OH) (rL3PL3), were in similar structure but had different hydrophilic components and surface charges, thus leading to different capabilities in gene delivery and expression in skeletal muscle. rL2PL2 was more efficient than Pluronic L64 and rL3PL3 when mediating luciferase, β-galactosidase, and fluorescent protein expressions. Furthermore, rL2PL2-mediated growth-hormone-releasing hormone expression could significantly induce mouse body weight increase in the first 21 days after injection. In addition, both rL2PL2 and rL3PL3 showed good in vivo biosafety in local and systemic administration. Altogether, rL2PL2-mediated gene expression in skeletal muscle exhibited applicable potential for gene therapy. The study revealed that the molecular structure and electric charge were critical factors governing the function of the copolymers for intramuscular gene delivery. It can be concluded that, combined with the previous study, both structural arrangements either reverse or similar to the biomembrane are effective in designing such copolymers. It also provides an innovative way in designing and synthesizing new electroneutralized triblock copolymers, which could be used safely and efficiently for intramuscular gene delivery

Reconstruction of global gridded monthly sectoral water withdrawals for 1971-2010 and analysis of their spatiotemporal patterns

Human water withdrawal has increasingly altered the global water cycle in past decades, yet our understanding of its driving forces and patterns is limited. Reported historical estimates of sectoral water withdrawals are often sparse and incomplete, mainly restricted to water withdrawal estimates available at annual and country scale, due to a lack of observations at local and seasonal time scales. In this study, through collecting and consolidating various sources of reported data and developing spatial and temporal statistical downscaling algorithms, we reconstruct a global monthly gridded (0.5 degree) sectoral water withdrawal dataset for the period 1971–2010, which distinguishes six water use sectors, i.e. irrigation, domestic, electricity generation (cooling of thermal power plants), livestock, mining, and manufacturing. Based on the reconstructed dataset, the spatial and temporal patterns of historical water withdrawal are analyzed. Results show that global total water withdrawal has increased significantly during 1971–2010, mainly driven by the increase of irrigation water withdrawal. Regions with high water withdrawal are those densely populated or with large irrigated cropland production, e.g., the United States (US), eastern China, India, and Europe. Seasonally, irrigation water withdrawal in summer for the major crops contributes a large percentage of annual total irrigation water withdrawal in mid and high-latitude regions, and the dominant season of irrigation water withdrawal is also different across regions. Domestic water withdrawal is mostly characterized by a summer peak, while water withdrawal for electricity generation has a winter peak in high-latitude regions and a summer peak in low-latitude regions. Despite the overall increasing trend, irrigation in the western US and domestic water withdrawal in western Europe exhibit a decreasing trend. Our results highlight the distinct spatial pattern of human water use by sectors at the seasonal and annual scales. The reconstructed gridded water withdrawal dataset is open-access, and can be used for examining issues related to water withdrawals at fine spatial, temporal and sectoral scales

On the density and multiplicity of solutions to the fractional Nirenberg problem

This paper is devoted to establishing some results on the density and multiplicity of solutions to the fractional Nirenberg problem which is equivalent to studying the conformally invariant equation $P_\sigma(v)=K v^{\frac{n+2\sigma}{n-2\sigma}}$ on the standard unit sphere $(\mathbb{S}^n,g_0)$ with $\sigma\in (0,1)$ and $n\geq 2$, where $P_\sigma$ is the intertwining operator of order $2\sigma$ and $K$ is the prescribed curvature function. More specifically, by using the variational gluing method, refined analysis of bubbling behavior, extension formula, as well as the blow up analysis arguments, we obtain the existence of infinitely many multi-bump solutions. In particular, we show the smooth curvature functions of metrics conformal to $g_0$ are dense in the $C^{0}$ topology. Moreover, the related fractional Laplacian equations $(-\Delta)^{\sigma} u=K(x) u^{\frac{n+2\sigma}{n-2\sigma}}$ in $\mathbb{R}^n$, with $K(x)$ being asymptotically periodic in one of the variables, are also studied and infinitely many solutions are obtained under natural flatness assumptions

On the CR Nirenberg problem: density and multiplicity of solutions

We prove some results on the density and multiplicity of positive solutions to the prescribed Webster scalar curvature problem on the $(2n+1)$-dimensional standard unit CR sphere $(\mathbb{S} ^{2n+1},\theta_0)$. Specifically, we construct arbitrarily many multi-bump solutions via the variational gluing method. In particular, we show the Webster scalar curvature functions of contact forms conformal to $\theta_0$ are $C^{0}$-dense among bounded functions which are positive somewhere. Existence results of infinitely many positive solutions to the related equation $-\Delta_{\mathbb{H}} u=R(\xi) u^{(n+2) /n}$ on the Heisenberg group \Hn with $R(\xi)$ being asymptotically periodic with respect to left translation are also obtained. Our proofs make use of a refined analysis of bubbling behavior, gradient flow, Pohozaev identity, as well as blow up arguments