Clinical outcome and hemodynamic behavior of the Labcor Dokimos Plus aortic valve

Die Labcor Dokimos Plus Bioprothese zeigte intraoperativ keine Komplikationen und postoperativ zufriedenstellende klinische Ergebnisse mit niedriger Morbidität und Mortalität. Die hämodynamischen Eigenschaften der Prothese waren ebenfalls zufriedenstellend.The Labcor Dokimos Plus bioprosthesis showed operatively no peculiarities and a satisfactory clinical outcome with low perioperative morbidity and mortality. The hemodynamic performance of the implanted valve sizes was satisfactory

Alpha oscillations do not implement gain control in early visual cortex but rather gating in parieto-occipital regions

Spatial attention provides a mechanism for, respectively, enhancing relevant and suppressing irrelevant information. While it is well established that attention modulates oscillations in the alpha band, it remains unclear if alpha oscillations are involved in directly modulating the neuronal excitability associated with the allocation of spatial attention. In this study, in humans, we utilized a novel broadband frequency (60–70 Hz) tagging paradigm to quantify neuronal excitability in relation to alpha oscillations in a spatial attention paradigm. We used magnetoencephalography to characterize ongoing brain activity as it allows for localizing the sources of both the alpha and frequency tagging responses. We found that attentional modulation of alpha power and the frequency tagging response are uncorrelated over trials. Importantly, the neuronal sources of the tagging response were localized in early visual cortex (V1) whereas the sources of the alpha activity were identified around parieto-occipital sulcus. Moreover, we found that attention did not modulate the latency of the frequency tagged responses. Our findings point to alpha band oscillations serving a downstream gating role rather than implementing gain control of excitability in early visual regions

Clinical outcome and hemodynamic behavior of the Labcor Dokimos Plus aortic valve

Background The Labcor Dokimos Plus (LDP) is a stented externally mounted pericardial aortic bioprosthesis, which was recently introduced in Europe. Aims of the study are evaluation of operative and postoperative results as well as hemodynamic performance. Methods One hundred consecutive patients with a mean age of 65.9 ± 10.7 years (range 35–87) and a mean EuroSCORE II of 3.1 ± 3.9 (range 0.67–24.5) underwent aortic valve replacement with the LDP. Mean valve-size was 25.2 ± 1.7 mm. Concomitant procedures were performed in 34% of the cases. Postoperative clinical data were analyzed and hemodynamic performance of the prostheses was evaluated by transthoracic echocardiography. Clinical follow-up was 100%, echocardiographic follow-up was 93% complete. Results Intraoperatively no peculiarities occurred. Mean cross clamp times for isolated and complex procedures were 74.5 ± 20.0 min and 103.7 ± 37.1 min, respectively. Patients were extubated after a mean of 9.4 ± 15.8 h. There were no perioperative strokes. Bleeding events occurred in 4 patients. 30-day- mortality was 2%. One case of early endocarditis occurred. Echocardiography showed maximum and mean pressure gradients of 18.1 ± 6.4 and 9.6 ± 3.7 mmHg, respectively. Correspondingly to valve sizes 21, 23, 25 and 27 mm, mean pressure gradients were 17.3, 9.5, 8.5 and 10.2 mmHg, effective orifice areas were 1.92, 1.79, 2.0, 2.16 cm2 and indexed effective orifice areas were 1.08, 0.95, 0.99 and 1.01 cm2/m2, respectively. No relevant regurgitations occurred. Conclusions The LDP showed operatively no peculiarities and a satisfactory clinical outcome with low perioperative morbidity and mortality. The hemodynamic performance of the implanted valve sizes was satisfactory

Applying a proven filtering method to adjust the training sample of neural networks

The article notes the complexity and duration of the process of forming a training sample of a neural network, since the correctness of the sample is checked by assessing the quality of the network after its training, it also notes the negative impact of the commonly used formal method of forming a training sample of a neural network without taking into account the physical processes of data and signal transformation in real devices on the quality of the network when filtering the noise of the speech signal. Methods and means for filtering the noise of speech signals are described. To solve the filtering problem, a sequence of main stages of processing a speech signal containing noise is presented, and their description is given. The article proposes to choose a filtering method based on the analysis of noise characteristics, while it is recommended to distinguish between homogeneous (monotonic) and dynamically changing (random) noise, for which filtering methods are different. When choosing a filtering method, it is proposed to take into account the degree of correspondence between the frequency range of the noise and the speech signal. As the main way to reduce noise, an approach is proposed based on the use of an improved and proven method for filtering noise by subtracting the spectral components of noise from the spectrum of a signal containing noise. This approach is proposed to be used for the formation and correction of a training set for a neural network designed to reduce noise in a speech signal. The results of the practical application of the proven filtration method confirmed the feasibility of its application. An important result of the work presented in the article is the possibility of evaluating the feasibility of specific corrective changes in the neural network training set by comparing it with the filtering results of the modified and tested method

Interrelation Between the Changes of Phase Functions of Cardiac Muscle Contraction and Biochemical Processes as an Algorithm for Identifying Local Pathologies in Cardiovascular System

Aims The interrelation between hemodynamic changes, functions of the cardiovascular system and biochemical reactions in the cells of the heart muscle is investigated in the present paper. Materials and methods Several methods were used to influence the metabolism processes in the myocardium. The changes in the phase functions of contraction of different cardiac muscles were recorded. In order to have comprehensive influence on the metabolism processes, normalization of the acid-base balance was performed. L-carnitine and octolipen were used to affect the lipid metabolism. Results Phase blood volumes that are characteristic of hemodynamics changed in the course of treatment to reach their nornal values. The ECG shape during the heart cycle phases also changed to reach the norm. The initial ECG shape describing Brugada syndrome almost reached its normal value. Extrasystole disappeared therewith. Conclusion The method of the heart cycle phase analysis enables monitoring any changes in hemodynamics and functions of the cardiovascular system. The method can be used for identifying the original cause of pathologies and efficient monitoring of the treatment progress

Vector of Development of Modern Film Festivals in Yekaterinburg

Объектом исследования в статье является кинофестивальное движение в Екатеринбурге, охватывающее период с 1988 года по настоящее время. В центре анализа - те фестивали, которые стали визитной карточкой уральского региона: Открытый фестиваль документального кино «Россия» и «Кинопроба» - международный фестиваль-практикум киношкол. Автор рассматривает также новые фестивали Екатеринбурга, в перспективе способные стать его культурными брендами, такие как «Ойка» и «Одна шестая».The object of research in the article is the film festival movement in Yekaterinburg, covering the period from 1988 to the present. In the center of the analysis are those festivals that have become the hallmark of the Ural region: the Open Documentary Film Festival “Russia” and “Kinoproba” - an international festival-workshop of film schools. The author also considers new festivals of Yekaterinburg, which in the future can become its cultural brands, such as “Oika” and “One Sixth”

The Ability of Quantum Dots Formation in Thin Nanostructured Amorphous Films

In the last years an interest in field of quantum dots devices creating has been increased. In this work the nanocrystallite with Frank-Kasper structure was examined as the quantum dot in amorphous film. An ability to create all-inorganic Quantum Dots Light Emission Device may be considered for Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films. The self-organisation of atomic structure in Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films, which possess large values of perpendicular magnetic anisotropy (PMA) constant (K ⊥ ~ 10 erg/cm ), were investigated by methods of electron diffraction and transmission electron microscopy, including the method of bend contours. The crystallization of the films proceeds in an explosive way forming different dissipative structures from initial nanocrystalline state. In previous works [2, 3] it was shown that after crystallization (Т ann ~ 260-330 °C) the atomic structures of Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films are tetrahedrally close-packed Frank-Kasper structures. In this work the structural model of thin film at mesoscale and its correlation with magnetic and optical properties is proposed.В последние годы большой интерес привлекают исследования, связанные с устройствами, работающими на квантовых точках. В данной статье нанокристаллиты со структурами Франка-Каспера исследованы как квантовые точки в аморфных пленках. Возможность создания эмиссионных устройств на полностью неорганических квантовых точках может быть рассмотрена для Co 80 C 20 , Tb 30 Fe 70 , Fe 86 Mn 13 C и Co 50 Pd 50 пленок. Самоорганизация атомнойструктуры Co 80 C 20 , Tb 30 Fe 70 , Fe 86 Mn 13 C и Co 50 Pd 50 в пленках, которые обладают высокими значениями константы, перпендикулярной магнитной анизотропии (ПМА) K ⊥ ~ 10 эрг/см , исследованы методами электронной дифракции и просвечивающей электронной микроскопии, включая метод изгибных контуров. Процессы взрывной кристаллизации аморфных пленок формируют различные диссипативные структуры из нанокристаллических зародышей. В предыдущих работах [2, 3] было показано, что после кристаллизации (Т отжига ~ 260-330 °C) атомная структура Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C и Co 50 Pd 50 была определена как тетраэдрически плотно упакованная структура Франка Каспера. В этих работах структурные модели тонких пленок, созданные для микро-и мезомасштабов связываются с магнитными и оптическими свойствами пленок