Deep Learning the Effects of Photon Sensors on the Event Reconstruction Performance in an Antineutrino Detector

We provide a fast approach incorporating the usage of deep learning for evaluating the effects of photon sensors in an antineutrino detector on the event reconstruction performance therein. This work is an attempt to harness the power of deep learning for detector designing and upgrade planning. Using the Daya Bay detector as a benchmark case and the vertex reconstruction performance as the objective for the deep neural network, we find that the photomultiplier tubes (PMTs) have different relative importance to the vertex reconstruction. More importantly, the vertex position resolutions for the Daya Bay detector follow approximately a multi-exponential relationship with respect to the number of PMTs and hence, the coverage. This could also assist in deciding on the merits of installing additional PMTs for future detector plans. The approach could easily be used with other objectives in place of vertex reconstruction

DETC2005-84370 STUDY ON THE SENSITIVITY OF CONTROLLABLE PARAMETERS IN AN ACTIVE VIBRATION ISOLATION SYSTEM OF AIR SPRING WITH RUBBER BELLOW

ABSTRACT The characteristics of control parameters of air spring with rubber bellow are analyzed through finite element method and thermodynamic equation respectively. The analysis results indicate that the vertical stiffness of air spring is sensitive to the varying of vertical displacement and volume, and nonlinearly varies with vertical displacement. When the air spring is pressed down or pulled up under the exterior excitation, the height of air spring can be controlled to keep stable through adjusting the volume of air spring by the use of hydraulic transformer

Antioxidant and antibacterial activity of Toddalia asiatica (Linn) Lam root extracts

Background: Toddalia asiatica (Linn) Lam is a woody vine that is used medicinally in China, India, and East Africa. The aim of the present study was to examine the antioxidant and antibacterial activity of the roots of Toddalia asiatica (Linn) Lam (TA).Materials and Methods: The antioxidant capacity of TA roots was determined using 1,1 iphenyl-2-picrylhydrazyl (DPPH), 2,2´-azino-bis (3-ethylbenzo-thiazoline-6-sulfonicacid) (ABTS), and the ferric reducing antioxidant potential (FRAP) assay. The antimicrobial activity of TA against Staphylococcus aureus (SA), methicillin-resistant S. aureus (MRSA), and extended spectrum β-lactamase positive S. aureus (ESBLs-SA) was screened.Results: Methanol and ethyl acetate extracts of TA exhibited strong antioxidant activity. The methanol extract had the highest antioxidant activity (DPPH, IC50=41.45 μg/mL; ABTS, IC50=8.34 μg/mL; FRAP=1304.8 ± 60.38 μmol Trolox equivalent (TE)/g), which was close to that of the positive control, butylated hydroxytoluene (BHT). The petroleum ether extract of TA showed the highest antimicrobial activity (SA, minimum inhibitory concentration (MIC) = 250 μg/disc; MRSA, MIC=125 μg/disc) when compared with that of ethyl acetate extract (SA, MIC=250 μg/disc) and methanol extract.Conclusions: Investigation of methanol, petroleum ether, and ethyl acetate extracts of TA root revealed robust antioxidant activity in methanol extracts and strong antimicrobial activity against SA and MRSA in petroleum ether extracts.Keywords: Toddalia asiatica (Linn) Lam; antioxidant; antibacteria

Longitudinal optical conductivities in tilted Dirac bands

We report a unified theory based on linear response, for analyzing the longitudinal optical conductivity (LOC) of materials with tilted Dirac cones. Depending on the tilt parameter $t$, the Dirac electrons have four phases, untilted, type-I, type-II, and type-III; the Dirac dispersion can be isotropic or anisotropic; the spatial dimension of the material can be one-, two-, or three-dimensions. The interband LOCs and intraband LOCs in $d$ dimension (with $d\ge2$) are found to scale as to $\sigma_{0}\omega^{d-2}$ and $\sigma_{0}|\mu|^{d-1}\delta(\omega)$, respectively, where $\omega$ is the frequency and $\mu$ the chemical potential. The interband LOCs always vanish in one dimension due to lacking of extra spatial dimension. The angular dependence of LOCs is found to characterize the band tilting, and the constant asymptotic background values of LOC reflect features of the Dirac bands. The LOCs in the anisotropic tilted Dirac cone can be connected to its isotropic counterpart by a ratio that consists of Fermi velocities. The findings are valid for a great many Dirac materials in the spatial dimensions of physical interests.Comment: 11 pages, 3 figure

(2R,4R)-1-(tert-But­oxy­carbon­yl)-4-meth­oxy­pyrrolidine-2-carb­oxy­lic acid

In the title compound, C11H19NO5, the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the meth­oxy group are 59.50 (3) and 62.02 (1)°, respectively. In the crystal, inter­molecular O—H⋯O hydrogen bonds link the mol­ecules into chains along [100]. The absolute configuration is assigned in accord with that of (2R,4R)-1-(tert-but­oxy­carbon­yl)-4-hy­droxy­pyrrolidine-2-carb­oxy­lic acid, which was the starting material in the synthesis

Comparative Pharmacokinetics of Orbifloxacin Following a Single Intravenous or Oral Administration to Healthy and Diabetic Rats

The single-dose disposition kinetics of orbifloxacin was determined in clinically healthy and diabetic rats  after intravenous or oral administration of 5 mg/kg body weight. Orbifloxacin concentrations were determined  by HPLC with fluorescence detection. The HPLC method was sensitive, specific and repeatable. A  systemic bioavailability of 99.1% and 108 %, and a Cmax of 6.55 } 1.09 μg /mL and 8.63 } 1.09 μg /mL were  observed in healthy and diabetic rats, respectively. The terminal half-life after intravenous and oral administration  was 4.17 } 0.38 h and 4.03 } 0.41 h for healthy and 2.31 } 0.34 h and 3.03 } 0.28 h for diabetic  rats. Orbifloxacin was cleared more rapidly in diabetic rats (0.15 } 0.01 L/kg.h) than healthy group (0.11 }  0.01 L/kg.h), with longer mean resident time (MRT) values observed in the latter. Other kinetic parameters  were almost the same between the healthy and diabetic groups. This investigation revealed that a dose of 5  mg/kg orbifloxacin can be safely and effectively used to combat infections in rats of either group associated  with susceptible bacteria.

4-(3-Fluoro-4-nitro­phen­yl)morpholin-3-one

In the title compound, C10H9FN2O4, the dihedral angle between the benzene ring and the nitro group plane is 11.29 (3)°. The morpholinone ring adopts a twist-chair conformation. In the crystal, mol­ecules are linked by inter­molecular C—H⋯O hydrogen bonds into a chain along the a-axis direction