Embedded Applications of MS-PSO-BP on Wind/Storage Power Forecasting

Higher proportion wind power penetration has great impact on grid operation and dispatching, intelligent hybrid algorithm is proposed to cope with inaccurate schedule forecast. Firstly, hybrid algorithm of MS-PSO-BP (Mathematical Statistics, Particle Swarm Optimization, Back Propagation neural network) is proposed to improve the wind power system prediction accuracy. MS is used to optimize artificial neural network training sample, PSO-BP (particle swarm combined with back propagation neural network) is employed on prediction error dynamic revision. From the angle of root mean square error (RMSE), the mean absolute error (MAE) and convergence rate, analysis and comparison of several intelligent algorithms (BP, RBP, PSO-BP, MS-BP, MS-RBP, MS-PSO-BP) are done to verify the availability of the proposed prediction method. Further, due to the physical function of energy storage in improving accuracy of schedule pre-fabrication, a mathematical statistical method is proposed to determine the optimal capacity of the storage batteries in power forecasting based on the historical statistical data of wind farm. Algorithm feasibility is validated by application of experiment simulation and comparative analysis

Identification and analysis of phosphorylation status of proteins in dormant terminal buds of poplar

<p>Abstract</p> <p>Background</p> <p>Although there has been considerable progress made towards understanding the molecular mechanisms of bud dormancy, the roles of protein phosphorylation in the process of dormancy regulation in woody plants remain unclear.</p> <p>Results</p> <p>We used mass spectrometry combined with TiO₂phosphopeptide-enrichment strategies to investigate the phosphoproteome of dormant terminal buds (DTBs) in poplar (<it>Populus simonii × P. nigra</it>). There were 161 unique phosphorylated sites in 161 phosphopeptides from 151 proteins; 141 proteins have orthologs in <it>Arabidopsis</it>, and 10 proteins are unique to poplar. Only 34 sites in proteins in poplar did not match well with the equivalent phosphorylation sites of their orthologs in <it>Arabidopsis</it>, indicating that regulatory mechanisms are well conserved between poplar and <it>Arabidopsis</it>. Further functional classifications showed that most of these phosphoproteins were involved in binding and catalytic activity. Extraction of the phosphorylation motif using Motif-X indicated that proline-directed kinases are a major kinase group involved in protein phosphorylation in dormant poplar tissues.</p> <p>Conclusions</p> <p>This study provides evidence about the significance of protein phosphorylation during dormancy, and will be useful for similar studies on other woody plants.</p

[μ-11,23-Dibromo-3,7,15,19-tetra­aza­tri­cyclo­[19.3.1.19,13]hexa­cosa-1(25),2,7,9,11,13(26),14,19,21,23-deca­ene-25,26-diolato-κ4 N 3,N 7,O,O′:κ4 O,O′,N 15,N 19]bis[perchloratocopper(II)]

The title complex, [Cu2(C22H20Br2N4O2)(ClO4)2], was prepared by the condensation of 2,6-diformyl-4-bromo­phenol with 1,3-diamino­propane in the presence of copper(II) ions. The macrocyclic ligand shows an approximately planar structure except for the two propene groups in the macrocycle. The coordination polyhedron of each Cu atom can be described as distorted square pyramidal. The two Cu atoms are bridged by two phenolate O atoms of the macrocycle, with a Cu⋯Cu distance of 3.109 (2) Å

Strangeon matter and strangeon stars in a linked bag model

Inspired by various astrophysical phenomenons, it was suggested that pulsar-like compact stars may in fact be strangeon stars, comprised entirely of strangeons (quark-clusters with three-light-flavor symmetry) and a small amount of electrons. To examine such possibilities, in this work we propose a linked bag model, which can be adopted for strong condensed matter in both 2-flavoured (nucleons) and 3-flavoured (hyperons, strangeons, etc.) scenarios. The model parameters are calibrated to reproduce the saturation properties of nuclear matter, which are later applied to hyperonic matter and strangeon matter. The obtained energy per baryon of strangeon matter is reduced if we adopt larger quark numbers inside a strangeon, which stiffens the equation of state and consequently increases the maximum mass of strangeon stars. In a large parameter space, the maximum mass and tidal deformability of strangeon stars predicted in the linked bag model are consistent with the current astrophysical constraints. It is found that the maximum mass of strangeon stars can be as large as $\sim 2.5M_\odot$, while the tidal deformability of a $1.4M_\odot$ strangeon star lies in the range of $180\lesssim \Lambda_{1.4} \lesssim 340$. More refined theoretical efforts as well as observational tests to these results are necessary in the future

Thio­phene-2-carbaldehyde 2,4-dinitro­phenyl­hydrazone

In the approximately planar molecule of the title compound, C11H8N4O4S, the dihedral angle between the thio­phene and benzene rings is 5.73 (10)°. In the crystal structure, bifurcated inter/intra­molecular N—H⋯(O,O) hydrogen bonds are present. The intermolecular links lead to inversion dimers containing an R 2 2(12) graph-set motif

1-Bromo-2,7-di-tert-butyl­pyrene

In the title mol­ecule, C24H25Br, one of two tert-butyl groups is rotationally disordered between two orientations in a 0.59 (3):0.41 (3) ratio. The crystal packing exhibits no π–π inter­actions; however, relatively short inter­molecular Br⋯Br contacts of 3.654 (1) Å are observed

Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo

INTRODUCTION: Breast cancer is the leading cause of cancer death in women worldwide. Elevated expression of c-Myc is a frequent genetic abnormality seen in this malignancy. For a better understanding of its role in maintaining the malignant phenotype, we used RNA interference (RNAi) directed against c-Myc in our study. RNAi provides a new, reliable method to investigate gene function and has the potential for gene therapy. The aim of the study was to examine the anti-tumor effects elicited by a decrease in the protein level of c-Myc by RNAi and its possible mechanism of effects in MCF-7 cells. METHOD: A plasmid-based polymerase III promoter system was used to deliver and express short interfering RNA (siRNA) targeting c-myc to reduce its expression in MCF-7 cells. Western blot analysis was used to measure the protein level of c-Myc. We assessed the effects of c-Myc silencing on tumor growth by a growth curve, by soft agar assay and by nude mice experiments in vivo. Standard fluorescence-activated cell sorter analysis and TdT-mediated dUTP nick end labelling assay were used to determine apoptosis of the cells. RESULTS: Our data showed that plasmids expressing siRNA against c-myc markedly and durably reduced its expression in MCF-7 cells by up to 80%, decreased the growth rate of MCF-7 cells, inhibited colony formation in soft agar and significantly reduced tumor growth in nude mice. We also found that depletion of c-Myc in this manner promoted apoptosis of MCF-7 cells upon serum withdrawal. CONCLUSION: c-Myc has a pivotal function in the development of breast cancer. Our data show that decreasing the c-Myc protein level in MCF-7 cells by RNAi could significantly inhibit tumor growth both in vitro and in vivo, and imply the therapeutic potential of RNAi on the treatment of breast cancer by targeting overexpression oncogenes such as c-myc, and c-myc might be a potential therapeutic target for human breast cancer

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

<p>Abstract</p> <p>Background</p> <p>MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including glioblastoma. Recent studies have reported that miR-221/222 regulate cell growth and cell cycle progression by targeting p27 and p57. However the underlying mechanism involved in cell survival modulation of miR-221/222 remains elusive.</p> <p>Results</p> <p>Here we showed that miR-221/222 inhibited cell apoptosis by targeting pro-apoptotic gene PUMA in human glioma cells. Enforced expression of miR-22/222 induced cell survival whereas knockdown of miR-221/222 rendered cells to apoptosis. Further, miR-221/222 reduced PUMA protein levels by targeting PUMA-3'UTR. Introducing PUMA cDNA without 3'UTR abrogated miR-221/222-induced cell survival. Notably, knockdown of miR-221/222 induces PUMA expression and cell apoptosis and considerably decreases tumor growth in xenograft model. Finally, there was an inverse relationship between PUMA and miR-221/222 expression in glioma tissues.</p> <p>Conclusion</p> <p>To our knowledge, these data indicate for the first time that miR-221/222 directly regulate apoptosis by targeting PUMA in glioblastoma and that miR-221/222 could be potential therapeutic targets for glioblastoma intervention.</p