The SS- and PP-wave fully charmed tetraquark states and their radial excitations

Inspired by recent progresses in observations of the fully charmed tetraquark states by LHCb, CMS, and ATLAS Collaborations, we perform a systematic study of the ground states and the first radial excitations of the $S$- and $P$-wave $\mathrm{cc}\bar{\mathrm{c}}\bar{\mathrm{c}}$ system. Their mass spectra, root mean square(r.m.s.) radii and radial density distributions are studied with the relativized quark model. The calculations show that there is no stable bound states for the full-charmed tetraquark states, and the r.m.s. radii of these tetraquark states are smaller than 1 fm. Our results support assigning X(6600) structure, $M_{X(6600)}=6552\pm10\pm12$ MeV, as one of the $0^{++}$(1$S$) and $2^{++}$(1$S$) states or their mixtures. Another structure also named as X(6600) by CMS Collaboration, $M_{X(6600)}=6.62\pm0.03^{+0.02}_{-0.01}$ GeV, may arise from the lowest 1$P$ states with $J^{PC}$=$0^{-+}$, $1^{-+}$, and $2^{-+}$. The possible assignments for X(6900) include the $0^{++}$(2$S$), $2^{++}$(2$S$) states, and the highest 1$P$ state with $J^{PC}=0^{-+}$. As for X(7200), it can be interpreted as one of the highest 2$P$ states with $J^{PC}=0^{-+}$, $1^{-+}$, and $2^{-+}$, and the 3$S$ states can not be completely excluded from the candidates.Comment: to be published in European Physical Journal

Systematic analysis of doubly charmed baryons Ξcc\Xi_{cc} and Ωcc\Omega_{cc}

In this work, we perform a systematic study of the mass spectra, the root mean square(r.m.s.) radii and the radial density distributions of the doubly charmed baryons $\Xi_{cc}$ and $\Omega_{cc}$. The calculations are carried out in the frame work of Godfrey-Isgur (GI) relativized quark model, where the baryon is regarded as a real three-body system of quarks. Our results show that the excited energy of doubly charmed baryon with $\rho$-mode is lower than those of the $\lambda$-mode and $\lambda$-$\rho$ mixing mode, which indicates that the lowest state is dominated by the $\rho$-mode. According to this conclusion, we systematically investigate the mass spectra, the r.m.s. radii of the ground and excited states($1S\sim4S$, $1P\sim4P$, $1D\sim4D$, $1F\sim4F$ and $1G\sim4G$) with $\rho$-mode. Using the wave functions obtained from quark model, we also study the radial density distributions. Finally, with the predicated mass spectra, the Regge trajectories of $\Xi_{cc}$ and $\Omega_{cc}$ in the ($J$,$M^{2}$) plane are constructed, and the slopes, intercepts are determined by linear fitting. It is found that model predicted masses fit nicely to the constructed Regge trajectories.Comment: arXiv admin note: text overlap with arXiv:2206.0812

Strong decay properties of single heavy baryons ΛQ\Lambda_{Q}, ΣQ\Sigma_{Q} and ΩQ\Omega_{Q}

Motivated by recent progresses in experiments in searching for the $\Omega_{c}$ baryons, we systematically analyze the strong decay behaviors of single heavy baryons $\Lambda_{Q}$, $\Sigma_{Q}$ and $\Omega_{Q}$. The two-body strong decay properties of $S$-wave, $P$-wave and some $D$-wave states are studied with the $^{3}P_{0}$ model. The results support assigning the recently observed $\Omega_{c}(3185)$ and $\Omega_{c}(3327)$ as the 2S($\frac{3}{2}^{+}$) and 1D($\frac{3}{2}^{+}$) states, respectively. In addition, the quantum numbers of many other experimentally observed baryons are also suggested according to their strong decays. Finally, some baryons which have good potentials to be observed in experiments are predicted and the possible decay channels for searching for these predicted states are also suggested.Comment: arXiv admin note: substantial text overlap with arXiv:2206.0812

MicroRNAs in Human Pituitary Adenomas

MicroRNAs (miRNAs) are a class of recently identified noncoding RNAs that regulate gene expression at posttranscriptional level. Due to the large number of genes regulated by miRNAs, miRNAs play important roles in many cellular processes. Emerging evidence indicates that miRNAs are dysregulated in pituitary adenomas, a class of intracranial neoplasms which account for 10–15% of diagnosed brain tumors. Deregulated miRNAs and their targets contribute to pituitary adenomas progression and are associated with cell cycle control, apoptosis, invasion, and pharmacological treatment of pituitary adenomas. To provide an overview of miRNAs dysregulation and functions of these miRNAs in pituitary adenoma progression, we summarize the deregulated miRNAs and their targets to shed more light on their potential as therapeutic targets and novel biomarkers

Functional examination of novel kisspeptin phosphinic peptides

Kisspeptins acting on their cognate G protein-coupled receptor, kisspeptin receptor, play important roles in the suppression of cancer cell metastasis and regulation of the reproductive system, and therefore are important for therapeutic intervention. All native functional human kisspeptins (kisspeptin-54, kisspsptin-14 and kisspeptin-13) share the 10 amino acids of kisspeptin-10 at their C-terminus (45–54). However, they are inactivated rapidly by matrix metalloproteinases (MMPs) through the cleavage of the peptide bond between glycine51 and leucine52, which limits their clinical applications. Development of MMP-resistant analogues of kisspeptins may provide better therapeutic outputs. In the present study, two kisspeptin phosphinic peptides were designed and synthesized, and their ability to induce phosphorylation of ERK1/2 through kisspeptin receptor and their inhibition on MMP-2 and MMP-9 whose activity correlates with cancer metastasis were assessed. The results showed that one analogue, phosphinic kisspeptin R isomer (PKPR), exhibited kisspeptin receptor-agonistic activity and also inhibitory activity on MMP-2, indicating that PKPR may serve as a lead for the further development of kisspeptin analogues for therapeutic purpose

Probing Dirac Neutrino Properties with Dilepton Signature

The neutrinophilic two Higgs doublet model is one of the simplest models to explain the origin of tiny Dirac neutrino masses. This model introduces a new Higgs doublet with eV scale VEV to naturally generate the tiny neutrino masses. Depending on the same Yukawa coupling, the neutrino oscillation patterns can be probed with the dilepton signature from the decay of charged scalar $H^\pm$. For example, the normal hierarchy predicts BR$(H^+\to e^+\nu)\ll$ BR$(H^+\to \mu^+\nu)\approx$ BR$(H^+\to \tau^+\nu)\simeq0.5$ when the lightest neutrino mass is below 0.01 eV, while the inverted hierarchy predicts BR$(H^+\to e^+\nu)/2\simeq$ BR$(H^+\to \mu^+\nu)\simeq$ BR$(H^+\to \tau^+\nu)\simeq0.25$. By precise measurement of BR$(H^+\to \ell^+\nu)$, we are hopefully to probe the lightest neutrino mass and the atmospheric mixing angle $\theta_{23}$. Through the detailed simulation of the dilepton signature and corresponding backgrounds, we find that the 3 TeV CLIC could discover $M_{H^+}\lesssim1220$ GeV for NH and $M_{H^+}\lesssim1280$ GeV for IH. Meanwhile, the future 100 TeV FCC-hh collider could probe $M_{H^+}\lesssim1810$ GeV for NH and $M_{H^+}\lesssim2060$ GeV for IH.Comment: 18 pages, 9 figure

Conformal Three-Dimensional Interphase of Li Metal Anode Revealed by Low Dose Cryo-Electron Microscopy

Using cryogenic transmission electron microscopy, we revealed three dimensional (3D) structural details of the electrochemically plated lithium (Li) flakes and their solid electrolyte interphase (SEI), including the composite SEI skin-layer and SEI fossil pieces buried inside the Li matrix. As the SEI skin-layer is largely comprised of nanocrystalline LiF and Li2O in amorphous polymeric matrix, when complete Li stripping occurs, the compromised SEI three-dimensional framework buckles, forming nanoscale bends and wrinkles. We showed that the flexibility and resilience of the SEI skin-layer plays a vital role in preserving an intact SEI 3D framework after Li stripping. The intact SEI network enables the nucleation and growth of the newly plated Li inside the previously formed SEI network in the subsequent cycles, preventing additional large amount of SEI formation between newly plated Li metal and the electrolyte. In addition, cells cycled under the accurately controlled uniaxial pressure can further enhance the repeated utilization of the SEI framework and improve the coulombic efficiency (CE) by up to 97%, demonstrating an effective strategy of reducing the formation of additional SEI and inactive dead Li. The identification of such flexible and porous 3D SEI framework clarifies the working mechanism of SEI in lithium metal anode for batteries. The insights provided in this work will inspire researchers to design more functional artificial 3D SEI on other metal anodes to improve rechargeable metal battery with long cycle life

A tetra­nuclear cobalt(III) cluster with 2-(hydroxy­meth­yl)pyridine ligands

In the title compound, tetra­kis[μ3-(2-pyrid­yl)methano­lato]tetra­kis[bromido(methanol)cobalt(III)] tetra­bromide 2-(hydroxy­meth­yl)pyridine tetra­solvate dihydrate, [Co4Br4(C6H6NO)4(CH3OH)4]Br4·4C6H7NO4·2H2O, the cation comprises a [Co4O4] cubane-type core ( symmetry). The four CoIII ions and bridging O atoms from four (2-pyrid­yl)methano­late anions are located at alternating vertices of the cube, with bromide ions and methanol ligands on the exterior of the core, completing a distorted octa­hedral geometry. The structure is stablized by inter­molecular O—H⋯Br and O—H⋯O inter­actions