713 research outputs found

    Oscillation of solutions for second-order nonlinear difference equations with nonlinear neutral term

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    AbstractSome Riccati type difference inequalities are given for the second-order nonlinear difference equations with nonlinear neutral term. and using these inequalities, we obtain some oscillation criteria for the above equation

    Effects of four polyphenols on mouse wound healing and the gene expression profile of resveratrol action

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    Studies have demonstrated the potent effects of polyphenols on cutaneous wound healing. However, the molecular mechanisms underlying polyphenol activity are incompletely understood. Herein, mice were experimentally wounded, intragastrically treated with four polyphenols, resveratrol, tea polyphenols, genistein, and quercetin; and monitored for 14 days. Resveratrol was the most effective compound, promoting wound healing starting at day 7 after wounding, by enhancing cell proliferation and reducing apoptosis and subsequently promoting epidermal and dermal repair, collagen synthesis and scar maturation. RNA sequencing was performed in control and resveratrol-treated tissues on day 7 after wounding. Resveratrol treatment upregulated 362 genes and downregulated 334 genes. Gene Ontology enrichment analysis showed that differentially expressed genes (DEGs) were associated with different biological processes (keratinization, immunity, and inflammation), molecular functions (cytokine and chemokine activities), and cellular components (extracellular region and matrix). Kyoto Encyclopedia of Genes and Genomes pathway analysis indicated that DEGs were predominantly enriched in inflammatory and immunological pathways, including cytokine-cytokine receptor interaction, chemokine signaling, and tumor necrosis factor (TNF) signaling. These results show that resveratrol accelerates wound healing by promoting keratinization and dermal repair and attenuating immune and inflammatory responses

    A New Scheme and Microstructural Model for 3D Full 5-directional Braided Composites

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    AbstractThree-dimensional(3D) braided composites are a kind of advanced ones and are used in the aeronautical and astronautical fields more widely. The advantages, usages, shortages and disadvantages of 3D braided composites are analyzed, and the possible approach of improving the properties of the materials is presented, that is, a new type of 3D full 5-directional braided composites is developed. The methods of making this type of preform are proposed. It is pointed out that the four-step braiding which is the most possible to realize industrialized production almost has no effect on the composites'properties. By analyzing the simulation model, the advantages of the material compared with the 3D 4-di- rectional and 5-directional materials are presented. Finally, a microstructural model is analyzed to lay the foundation for the future theoretical analysis of these composites

    Oscillation of second order self-conjugate differential equation with impulses

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    AbstractIn this paper, we investigate the oscillation of second-order self-conjugate differential equation with impulses(1)(a(t)(x(t)+p(t)x(t-τ))′)′+q(t)x(t-σ)=0,t≠tk,t⩾t0,(2)x(tk+)=(1+bk)x(tk),k=1,2,…,(3)x′(tk+)=(1+bk)x′(tk),k=1,2,…,where a,p,q are continuous functions in [t0,+∞), q(t)⩾0, a(t)>0, ∫t0∞(1/a(s))ds=∞, τ>0, σ>0, bk>-1, 0<t0<t1 <t2<⋯<tk<⋯ and limk→∞tk=∞. We get some sufficient conditions for the oscillation of solutions of Eqs. (1)–(3)

    Automatically Generating and Rendering Native Advertisements

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    Systems and methods for automatically generating and rendering a native advertisement for display on a client device when the client device is accessing a publisher’s webpage are described. A template node among a number of nodes of a publisher’s webpage can be selected to specify a content item that the publisher wants the native ad looks like. When the publisher’s webpage is loaded by a web browser of a client device, the native ad can be rendered by the browser using a JavaScript downloaded from an advertisement server. The rendering process can include extracting a number of formatting attributes for the native ad from the template node, mapping the formatting attributes with a proper template from a number of predefined templates maintained by an ad server, and loading the proper template from the ad server to render the content of the native advertisement in its corresponding inline frame
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