Differential measurement of atmospheric refraction with a telescope with double fields of view

For the sake of complete theoretical research of atmospheric refraction, the atmospheric refraction under the condition of lower angles of elevation is still worthy to be analyzed and explored. In some engineering applications, the objects with larger zenith distance must be observed sometimes. Carrying out observational research of the atmospheric refraction at lower angles of elevation has an important significance. It has been considered difficult to measure the atmospheric refraction at lower angles of elevation. A new idea for determining atmospheric refraction by utilizing differential measurement with double fields of view is proposed. Taking the observational principle of HIPPARCOS satellite as a reference, a schematic prototype with double fields of view was developed. In August of 2013, experimental observations were carried out and the atmospheric refractions at lower angles of elevation can be obtained by the schematic prototype. The measured value of the atmospheric refraction at the zenith distance of 78.8 degree is $240.23"\pm0.27"$, and the feasibility of differential measurement of atmospheric refraction with double fields of view was justified. The limitations of the schematic prototype such as inadequate ability of gathering light, lack of accurate meteorological data recording and lower automatic level of observation and data processing were also pointed out, which need to be improved in subsequent work.Comment: 10 pages, 6 figure

Unidirectional emission and nanoparticle detection in a deformed circular square resonator

We propose a novel deformed square resonator which has four asymmetric circular sides. Photons leak out from specific points, depending on the interplay between stable islands and unstable manifolds in phase space. By carefully breaking the mirror reflection symmetry, optical modes with strong chirality approaching 1 and unidirectional emission can be achieved simultaneously. Upon binding of a nanoparticle, the far-field emission pattern of the deformed microcavity changes drastically. Due to the EP point of the degenerate mode pairs in the deformed cavity, chirality-based far-field detection of nanoparticles with ultra-small size can be realized

Identification of a New HCV Subtype 6xg Among Injection Drug Users in Kachin, Myanmar

Characterizing hepatitis C virus (HCV) genetic diversity not only allows us to trace its origin and evolutionary history, but also provides valuable insights into diagnosis, prevention and therapy of HCV infection. Although eight HCV genotypes and 86 subtypes have been classified, there are still some HCV variants that need to be assigned. The genotype 6 is the most diverse HCV genotype and mainly prevalent in Southeast Asia. In this study, we identified a new HCV subtype 6xg from injection drug users (IDUs) in Kachin, Myanmar. A distinctive feature of 6xg from other subtypes of the genotype 6 was a Lys insertion in NS5A gene, which changes the RRKR/K motif into RRKKR/K. Bayesian analyses showed that HCV 6xg originated during 1984–1988, and experienced a rapid population expansion during 2005–2009. We characterized HCV subtype profile among IDUs in this region, and detected six HCV subtypes, including 1a (12.0%), 3a (12.0%), 3b (24.0%), 6n (16.0%), 6xa (20.0%), and 6xg (12.0%). Importantly, we found that HCV subtype distribution in Kachin was very similar to that in Dehong prefecture of Yunnan, but very distinct from those in other regions of Myanmar and Yunnan, indicating that the China–Myanmar border region shared a unique HCV subtype pattern. The appearance of 6xg and the unique HCV subtype profile among IDUs in the China–Myanmar border region have significant epidemiological and public health implications

1-(4-tert-Butyl­benz­yl)-3-phenyl-1H-pyrazole-5-carboxylic acid

In the title compound, C21H22N2O2, the mean plane of the pyrazole ring makes dihedral angles of 18.80 (12) and 77.13 (5)°, respectively, with the mean planes of the phenyl and tert-butyl­benzyl rings. The carboxylate group is inclined at 8.51 (14)° with respect to the pyrazole ring. The crystal structure displays inter­molecular O—H⋯O hydrogen bonding, generating centrosymmetric dimers