111 research outputs found

    Anderson acceleration for geometry optimization and physics simulation

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    Many computer graphics problems require computing geometric shapes subject to certain constraints. This often results in non-linear and non-convex optimization problems with globally coupled variables, which pose great challenge for interactive applications. Local-global solvers developed in recent years can quickly compute an approximate solution to such problems, making them an attractive choice for applications that prioritize efficiency over accuracy. However, these solvers suffer from lower convergence rate, and may take a long time to compute an accurate result. In this paper, we propose a simple and effective technique to accelerate the convergence of such solvers. By treating each local-global step as a fixed-point iteration, we apply Anderson acceleration, a well-established technique for fixed-point solvers, to speed up the convergence of a local-global solver. To address the stability issue of classical Anderson acceleration, we propose a simple strategy to guarantee the decrease of target energy and ensure its global convergence. In addition, we analyze the connection between Anderson acceleration and quasi-Newton methods, and show that the canonical choice of its mixing parameter is suitable for accelerating local-global solvers. Moreover, our technique is effective beyond classical local-global solvers, and can be applied to iterative methods with a common structure. We evaluate the performance of our technique on a variety of geometry optimization and physics simulation problems. Our approach significantly reduces the number of iterations required to compute an accurate result, with only a slight increase of computational cost per iteration. Its simplicity and effectiveness makes it a promising tool for accelerating existing algorithms as well as designing efficient new algorithms

    Fulvestrant, an estrogen receptor inhibitor, relieves postoperative hemorrhoid edema via up-regulation of miR- 424-5p

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    Purpose: To investigate estrogen receptor (ER) expression in postoperative hemorrhoid edema tissues, and the likely mechanism involved in fulvestrant-mediated reduction of postoperative hemorrhoid edema.Methods: One hundred and eighty-five patients admitted to Jinshan Hospital of Fudan University, Shanghai who accepted hemorrhoidectomy were enrolled in this study. Primary cells were extracted from the anal margin tissues of patients for the determination of changes in ERα and vascular endothelial growth factor (VEGF). In vitro cellular experiments were performed in primary vascular endothelial cells to verify whether ER promoted postoperative perianal edema via the miR-424-5p estrogen receptor α gene (ESR1) axis. The cells were exposed to Fulvestrant, estradiol, and miR-424-5p mimic. Changes in expressions of ERα and VEGF were determined.Results: Fourteen patients (7.57 %), comprising 2 males (2.60 %) and 12 females (11.1 %), developedpostoperative anal margin edema. There was a significant difference in the incidence of postoperative anal edema between males and females (p < 0.05). Both immunohistochemistry and immunoblotting revealed markedly higher ERα levels in postoperative anal edema tissues than in preoperative tissues (p < 0.05). Moreover, ERα level was regulated by estradiol, and miR-424-5p targeted the estrogen receptor α gene (ESR1).Conclusion: Estradiol inhibits miR-424-5p through ERα in perianal tissues after hemorrhoid surgery. It increases VEGF and promotes perianal edema. However, fulvestrant inhibits ERα, thereby reducing VEGF expression and mitigating postoperative hemorrhoid edema, and therefore, has potential application for the management of postoperative hemorrhoid edema

    OpenPerf: A Benchmarking Framework for the Sustainable Development of the Open-Source Ecosystem

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    Benchmarking involves designing scientific test methods, tools, and frameworks to quantitatively and comparably assess specific performance indicators of certain test subjects. With the development of artificial intelligence, AI benchmarking datasets such as ImageNet and DataPerf have gradually become consensus standards in both academic and industrial fields. However, constructing a benchmarking framework remains a significant challenge in the open-source domain due to the diverse range of data types, the wide array of research issues, and the intricate nature of collaboration networks. This paper introduces OpenPerf, a benchmarking framework designed for the sustainable development of the open-source ecosystem. This framework defines 9 task benchmarking tasks in the open-source research, encompassing 3 data types: time series, text, and graphics, and addresses 6 research problems including regression, classification, recommendation, ranking, network building, and anomaly detection. Based on the above tasks, we implemented 3 data science task benchmarks, 2 index-based benchmarks, and 1 standard benchmark. Notably, the index-based benchmarks have been adopted by the China Electronics Standardization Institute as evaluation criteria for open-source community governance. Additionally, we have developed a comprehensive toolkit for OpenPerf, which not only offers robust data management, tool integration, and user interface capabilities but also adopts a Benchmarking-as-a-Service (BaaS) model to serve academic institutions, industries, and foundations. Through its application in renowned companies and institutions such as Alibaba, Ant Group, and East China Normal University, we have validated OpenPerf's pivotal role in the healthy evolution of the open-source ecosystem

    Highly efficient room-temperature nonvolatile magnetic switching by current in Fe3GaTe2 thin flakes

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    Effectively tuning magnetic state by using current is essential for novel spintronic devices. Magnetic van der Waals (vdW) materials have shown superior properties for the applications of magnetic information storage based on the efficient spin torque effect. However, for most of known vdW ferromagnets, the ferromagnetic transition temperatures lower than room temperature strongly impede their applications and the room-temperature vdW spintronic device with low energy consumption is still a long-sought goal. Here, we realize the highly efficient room-temperature nonvolatile magnetic switching by current in a single-material device based on vdW ferromagnet Fe3GaTe2. Moreover, the switching current density and power dissipation are about 300 and 60000 times smaller than conventional spin-orbit-torque devices of magnet/heavymetal heterostructures. These findings make an important progress on the applications of magnetic vdW materials in the fields of spintronics and magnetic information storage.Comment: 18 page2, 4 figure

    Converting metal-organic framework particles from hydrophilic to hydrophobic by an interfacial assembling route

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    Here we propose to modify the hydrophilicity of metal-organic framework (MOF) particles by an interfacial assembling route, which is based on the surface-active nature of MOF particles. It was found that hydrophilic UiO-66-NH₂ particles can be converted to hydrophobic particles through an oil-water interfacial assembling route. The underlying mechanism for the conversion of UiO-66-NH₂ was investigated by X-ray photoelectron spectroscopy and FT-IR spectroscopy. It was revealed that the close assembly of UiO-66-NH₂ particles at the oil-water interface strengthens the coordination between organic ligands and metal ions, which results in a decrease in the proportion of hydrophilic groups on UiO-66-NH₂ particle surfaces. Hydrophobic UiO-66-NH₂ particles show improved adsorption capacity for dyes in organic solvents compared with pristine UiO-66-NH₂ particles. It is expected that the interfacial assembling route can be applied to the synthesis of different kinds of MOF materials with tunable hydrophilicity or hydrophobicity required for diverse applications

    Response of fatal landslides to precipitation over the Chinese Loess Plateau under global warming

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    Rain-induced loess landslides are especially prevalent in the Chinese Loess Plateau (CLP). Some became fatal landslide disasters, leading to numerous casualties and significant socioeconomic losses. Extreme precipitation is the main cause of landslide occurrence. Therefore, in this study we discuss the correlation between seven extreme precipitation indices, single continuous precipitation events and fatal landslides in the CLP using Pearson correlation analysis. We also predict future precipitation under climate changes using five optimal CMIP6 models. During the period 2004–2016, fatal landslides in the CLP increased at a rate of 0.6 per year, with frequent landslide events occurring especially in the central and southwestern parts of the CLP. We find that SDII (simple daily intensity precipitation index) and R×5day (max 5-day precipitation amount) show spatial distribution that are consistent with fatal landslides. Extreme precipitation events were frequent after year 2000; and several extreme precipitation indices show an increasing trend with a higher magnitude since 2000 than before 2000. In particular, in 2013 when the number of fatal landslides was as high as 17, SDII, R95pTOT (extremely wet days), R25mm (very heavy precipitation days), and R×5day all showed abrupt increases. Single continuous precipitation events have profound effects on fatal landslides. We show that single continuous precipitation events with cumulative precipitation of 185–235 mm and duration of 6 days or longer have the highest correlation with fatal landslides. As the increasing occurrence of extreme rainfall events by the global warming, the CLP may face more fatal landslides in the future, especially in the high emission scenario of greenhouse gases (GHGs)

    Two-dimensional atomic-scale ultrathin lateral heterostructures

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    Ultrathin lateral heterostructures of monolayer MoS2 and WS2 have successfully been realized with the metal-organic chemical vapor deposition method. Atomic-resolution HAADF-STEM observations have revealed that the junction widths of lateral heterostructures range from several nanometers to single-atom thickness, the thinnest heterojunction in theory. The interfaces are atomically flat with minimal mixing between MoS2 and WS2, originating from rapid and abrupt switching of the source supply. Due to one-dimensional interfaces and broken rotational symmetry, the resulting ultrathin lateral heterostructures, 1~2 mixed-dimensional structures, can show emergent optical/electronic properties. The MOCVD growth developed in this work allows us to access various ultrathin lateral heterostructures, leading to future exploration of their emergent properties absent in each component alone

    Electrical resistivity tomography revealing possible breaching mechanism of a Late Pleistocene long-lasted gigantic rockslide dam in Diexi, China

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    peer reviewedLandslide damming is a widespread phenomenon worldwide and significantly affects the evolution of fluvial landscapes. However, it is rarely witnessed from an antiquities perspective, and the case for observing their internal structure is challenging. We attempt to visualize the subsurface structure and understand the likely breaching mechanism of the late Pleistocene Diexi gigantic landslide dam (longevity of ~ 10 ka), using electrical resistivity tomography (ERT) method. Eight ERT measurements on the Diexi dam body revealed high resistivity zones near the periphery and lower resistivity zones in the middle portion of the profiles. Geomorphological mapping based on the LiDAR data determined the boundary of the landslide. Field investigation found that zones of low resistivity were connected to a ditched gully. Because breaching such an enormous lake with a total area of 21.4 km2 dammed by a gigantic landslide body with intact rocks was not likely by overtopping alone. The authors postulate that differential seepage of water from the gullies through the landslide debris could have accelerated the undercutting erosion of the otherwise stable Diexi dam. Utilizing geophysical techniques, along with field geomorphology works, can provide valuable information on the evolution of a gigantic paleo-landslide dam, which has real implications for the stability evaluation and forecast of future landslide dams

    Nearly-room-temperature ferromagnetism and tunable anomalous Hall effect in atomically thin Fe4CoGeTe2

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    Itinerant ferromagnetism at room temperature is a key ingredient for spin transport and manipulation. Here, we report the realization of nearly-room-temperature itinerant ferromagnetism in Co doped Fe5GeTe2 thin flakes. The ferromagnetic transition temperature TC (323 K - 337 K) is almost unchanged when thickness is down to 12 nm and is still about 284 K at 2 nm (bilayer thickness). Theoretical calculations further indicate that the ferromagnetism persists in monolayer Fe4CoGeTe2. In addition to the robust ferromagnetism down to the ultrathin limit, Fe4CoGeTe2 exhibits an unusual temperature- and thickness-dependent intrinsic anomalous Hall effect. We propose that it could be ascribed to the dependence of band structure on thickness that changes the Berry curvature near the Fermi energy level subtly. The nearly-room-temperature ferromagnetism and tunable anomalous Hall effect in atomically thin Fe4CoGeTe2 provide opportunities to understand the exotic transport properties of two-dimensional van der Waals magnetic materials and explore their potential applications in spintronics.Comment: 28 pages, 4 figures, 1 tabl
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