1,625 research outputs found
The Feedback Control Strategy of the Takagi-Sugeno Fuzzy Car-Following Model with Two Delays
Considering the driver’s sensing the headway and velocity the different time-varying delays exist, respectively, and the sensitivity of drivers changes with headway and speed. Introducing the fuzzy control theory, a new fuzzy car-following model with two delays is presented, and the feedback control strategy of the new fuzzy car-following model is studied. Based on the Lyapunov function theory and linear matrix inequality (LMI) approach, the sufficient condition that the existence of the fuzzy controller is given making the closed-loop system is asymptotic, stable; namely, traffic congestion phenomenon can effectively be suppressed, and the controller gain matrix can be obtained via solving linear matrix inequality. Finally, the simulation examples verify that the method which suppresses traffic congestion and reduces fuel consumption and exhaust emissions is effective
Two-photon interference with two independent pseudo-thermal sources
The nature of two-photon interference is a subject that has aroused renewed
interest in recent years and is still under debate. In this paper we report the
first observation of two-photon interference with independent pseudo-thermal
sources in which sub-wavelength interference is observed. The phenomenon may be
described in terms of the classical statistical distribution of the two sources
and their optical transfer functions.Comment: Phys. Rev. A 74, 053807 (2006
Correlated two-photon imaging with true thermal light
We report the first experimental demonstration of two-photon correlated
imaging with true thermal light from a hollow cathode lamp. The coherence time
of the source is much shorter than that of previous experiments using random
scattered light from a laser. A two-pinhole mask was used as object, and the
corresponding thin lens equation was well satisfied. Since thermal light
sources are easier to obtain and measure than entangled light it is conceivable
that they may be used in special imaging applications.Comment: 3 pages, 5 figures, accepted by Optics Letter
Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway.
Tumor recurrence remains an obstacle after liver surgery, especially in living donor liver transplantation (LDLT) for patients with hepatocellular carcinoma (HCC). The acute-phase liver graft injury might potentially induce poor response to chemotherapy in recurrent HCC after liver transplantation. We here intended to explore the mechanism and to identify a therapeutic target to overcome such chemoresistance. The associations among graft injury, overexpression of IP10 and multidrug resistant genes were investigated in a rat liver transplantation model, and further validated in clinical cohort. The role of IP10 on HCC cell proliferation and tumor growth under chemotherapy was studied both in vitro and in vivo. The underlying mechanism was revealed by detecting the activation of endoplasmic reticulum (ER) stress signaling pathways. Moreover, the effect of IP10 neutralizing antibody sensitizing cisplatin treatment was further explored. In rat liver transplantation model, significant up-regulation of IP10 associated with multidrug resistant genes was found in small-for-size liver graft. Clinically, high expression of circulating IP10 was significant correlated with tumor recurrence in HCC patients underwent LDLT. Overexpression of IP10 promoted HCC cell proliferation and tumor growth under cisplatin treatment by activation of ATF6/Grp78 signaling. IP10 neutralizing antibody sensitized cisplatin treatment in nude mice. The overexpression of IP10, which induced by liver graft injury, may lead to cisplatin resistance via ATF6/Grp78 ER stress signaling pathway. IP10 neutralizing antibody could be a potential adjuvant therapy to sensitize cisplatin treatment
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