Determining the effects of excess weight on renal cortical stiffness in children and adolescents with point Shear Wave Elastography.

Aim: To determine the early effects of excess weight on renal cortical stiffness in children and adolescents using point shear wave elastography (pSWE). Materials and methods: One hundred and forty-six overweight and obese children (43.2% male: mean age, 12.6 +/- 2.9 years: range 4.3-18) and 48 lean children (27.1% male: mean age, 12.4 +/- 3.4: range 4.8-18.9) were included in the study and control group, respectively. pSWE measurements of the two kidneys were performed. The mean value of shear wave velocity was compared between groups. Results: The mean shear wave velocity was 2.79 +/- 0.53 m/s for the control subjects and 3.09 +/- 0.59 m/s for the overweight-obese subjects. The differences between the two groups were statistically significant (p=0.001). There was no correlation between shear wave velocity and age or depth. A positive correlation was found between shear wave velocity and body mass index, body mass index-standard deviation score, Conclusion: Renal cortical stiffness was higher in children with excess weight than in lean children. This study is the first attempt at applying pSWE to investigate the early adverse effects of excess weight

Media use and attitudes towards screens in children aged 36-72 months; a cross-sectional, descriptive study

Introduction: The age at which children are introduced to media devices is becoming increasingly earlier. Studies regarding the media habits of young children have gained importance. The aim of the study was to describe the screen media habits (age of introduction media, time spend with screen, popular choices) of preschool children and to explore their relationship with household characteristics. Population and methods: Cross-sectional descriptive study; the parents of children aged 36-72 months who attended childcare centers in Kayseri, a central Anatolian city in Türkiye, completed a questionnaire on media habits of families and children. Results: There were 858 questionaires included. The proportion of children using screen media more than 2 h/day was 28%; 36% of children were introduced to media devices before the age of two. The most frequently used media tool was television (95%) and the program watched was cartoons for TV (86.7%). Children of highly educated parents had shorter TV, computer and smartphone screen time (p = 0.012, p = 0.007, p <0.01 for mother and p = 0.049, p = 0.032, p = 0.04 for father respectively). Introducing books in the first 6 months was associated with shorter daily screen time (p = 0.011, p = 0.009, p = 0.002 for TV, computer and smartphone,respectively). Parent’s time spent on TV was positively correlated with children’s time spent on TV (p <0.05, r = 0.354). Conclusion: Parents’ education levels, parents’ screen time and introducing book in early age was related to children’s media habits. Comprehensive studies are needed to explain this relationship more clearly

Model-driven Query Generation for Elasticsearch

Federated Conference on Computer Science and Information Systems (FedCSIS) -- SEP 09-12, 2018 -- Poznan, POLANDWOS: 000454652300118Elasticsearch is a distributed RESTful search engine, capable of solving growing number of use cases and can handle petabytes of data in seconds. However, Elasticsearch comes with a complex query language which causes a steep learning curve for the developers and, therefore, creation of queries can be difficult and time-consuming in many cases. Hence, in this paper, we introduce a Domain-specific Modeling Language (DSML), called Dimension Query Language (DQL), to support the model-driven development of Elasticsearch queries. Elasticsearch queries can be automatically generated from DQL models and DQL's IDE is capable of executing these auto-generated Elasticsearch queries on remote repositories. An evaluation of using DQL has been performed at the industrial level with the participation of a group of developers. The conducted evaluation showed that the use of the language significantly decreases the development time required for creating Elasticsearch queries. Finally, qualitative assessment, based on the developers' feedback, exposed how DQL facilitates the development of Elasticsearch queries.Inst Elect & Elect Engineers, Polish Informat Proc Soc, Polish Informat Proc Soc, Mazovia Chapter, Inst Elect & Elect Engineers Poland Sect Comp Soc Chapter, Syst Res Inst Polish Acad Sci, Warsaw Univ Technol, Wroclaw Univ Econ, Adam Mickiewicz Univ, Inst Elect & Elect Engineers Reg 8, Inst Elect & Elect Engineers Poland Sect, Inst Elect & Elect Engineers Comp Soc Tech Comm Intelligent Informat, Inst Elect & Elect Engineers Czechoslovakia Sect Comp Soc Chapter, Inst Elect & Elect Engineers Poland Sect Gdansk Comp Soc Chapter, SMC Tech Comm Computat Collect Intelligence, Inst Elect & Elect Engineers Poland Sect Syst Man & Cybernet Soc Chapter, Inst Elect & Elect Engineers Poland Sect Computat Intelligence Soc Chapter, Inst Elect & Elect Engineers Poland Sect Control Syst Soc Chapter, ACM Special Interest Grp Appl Comp, Int Federat Informat Proc, Polish Acad Sci, Comm Comp Sci, Polish Operat & Syst Res Soc, Mazovia Cluster ICT Poland, Eastern Cluster ICT Poland, Intel, Gambit, Samsung, Silver Bullet Labs, eSensei, Data Ctr PPNTYasar GroupWe would like to thank software developers from Galaksiya Information Technologies for their cooperation and valuable feedbacks. This work was supported by Yasar Group (http://yasar.com.tr/en/)

Effects of L-carnitine supplementation on respiratory distress syndrome development and prognosis in premature infants: A single blind randomized controlled trial

The aim of the present study was to investigate the efficacy of L-carnitine therapy on the occurrence and prognosis of respiratory distress syndrome (RDS). A single blind, randomized controlled trial study was conducted on 130 infants with gestational ages of 28-36 weeks. Infants were assigned to experimental groups (groups 1 and 2) and control groups (groups 3 and 4). Groups 1 and 3 consisted of infants with RDS, and groups 2 and 4 groups were composed of infants without RDS. The experimental groups were treated with carnitine. No statistically significant differences in serum carnitine levels were detected between the study and the control groups on day 1 of treatment (P=0.06). However, on day 7 of treatment, serum carnitine levels in the experimental groups were significantly increased (P=0.02), as compared with the control groups. The surfactant requirement value, which is how many rounds of surfactant therapy were required, was 1.56+/-0.97 in group 1, and 2.12+/-0.99 in group 3 (P<0.001). The mean duration of mechanical ventilation required was 3.04+/-3.60 days in group 1, and 4.73+/-5.63 days in group 3 (P<0.001). The present results indicate that carnitine supplementation in premature infants with RDS may help to increase carnitine levels, thus decreasing the duration of mechanical ventilation and surfactant requirement

functional outcome in late adolescence/early adulthood of patients with autism spectrum disorder and its relationships with parental burnout and depression: A preliminary multi-center, cross-sectional study.

The aim of this study is to determine the functioning of adults with autism spectrum disorders (ASDs) diagnosed in childhood and depression and burnout levels among their parents. A total of 261 adults with ASDs and their parents were recruited for the study. Both parents completed the Beck Depression and Maslach Burnout Inventories and reported the functioning of their adult offspring with ASDs. Only 5.4 % of our sample reported “good” or “very good” outcomes. The most common psychiatric comorbidities were intellectual disabilities and attention-deficit/hyperactivity disorder. Maternal burnout and depression scores were significantly elevated compared to those of fathers. There is an undeniable urgent need for more research to identify the needs of adults and families suffering from ASD. Modifications for those with ASD may have to be made for support in workplaces, achieving driving licenses, using public transportation and attendance at tertiary education