Effect of dietary protein level on gentamicin-induced nephrotoxicity in rats and on the circadian rhythms of food ingestion

All aminoglycosides have the potential to cause nephrotoxicity. Previous studies have shown that this toxicity was altered according to the macronutrient composition of dietary regimens offered to female rats. In a first study, adult female Sprague-Dawley rats adapted to a standard chow diet, the standard chow with 20% added casein or with 55% added casein were treated for 10 days with a nephrotoxic dose of gentamicin sulfate (40 mg/kg/day, i.p.) or a saline solution. Food ingestion patterns and gentamicin nephrotoxicity indices were measured. In a second study, rats were fed the same diets, however, the treatment given was a sham injection. Results suggest that chronic gentamicin treatment leads to a decrease in food intake and flattening of the rhythms of food ingestion. Also, chow feeding and chow added with 20% casein were found to be more protective against gentamicin-induced nephrotoxicity than chow added with 55% casein

Plasticité neuronale des voies périphériques et centrales contrôlant la prise alimentaire

PARIS-AgroParisTech Centre Paris (751052302) / SudocSudocFranceF

Determinants of body image disturbance and disordered eating behaviors among self-identified LGBTQ individuals

Abstract It has been previously established that sexual minorities are more likely to suffer from mental health illnesses due to experiencing unique stressors such as fear, anxiety, stigma, harassment, and prejudice. Results revealed two noteworthy mental health disorders reported by lesbian, gay, bisexual, transgender, and queer (LGBTQ) individuals, disordered eating behaviors and disturbed body image. Yet, a-priori studies revealed inconsistent results with regards to body image concerns and eating disorder symptoms and attitudes among sexual minorities. Therefore, this cross-sectional study aimed at investigating the occurrence of disordered eating behaviors (DEB) and body image disturbance (BID) among sexual minorities in Lebanon. Additionally, the correlation between several determinants of DEB and BID including fear of negative evaluation, generalized anxiety, social support, and harassment levels have been examined. Generally, the present study revealed that LGBTQ population scored higher than cisgender and heterosexual individuals for the mean and global scores of the EDE-Q6.0 and BAS-2. Only generalized anxiety and fear of negative evaluation scales were significantly associated with DEB and BID among different sexual orientation and gender identity individuals. Therefore, it is very important that health professionals working with such vulnerable populations meticulously assess for disordered eating behaviors and body image disturbance for better communication and management

Effectiveness of a Text Messaging Intervention on Intuitive Eating: A randomized controlled trial

Intuitive eating (IE) is a concept based on mind-body integration of instinct, emotion and rational thought, to improve eating behaviors, physical and mental health. Several attempts were developed to teach IE principles including text-messaging interventions given that they are easy to implement and low-cost

Sucrose solution intake and its schedule of access affect the response to chronic variable stress in mice

Sucrose solution intake and its schedule of access affect the response to chronic variable stress in mice. Experimental Biology Meetin