104 research outputs found

    Desafíos y oportunidades de la inteligencia artificial en la educación y en el mercado laboral

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    La educación es un factor que está en constante modificación, buscando solucionar los problemas de la sociedad y adaptarse a la evolución de la misma, los avances tecnológicos y el uso de la Inteligencia Artificial (IA), en los diversos sectores, comienza a obligar al educativo y al laboral a adoptarla. Es por ello que la presente investigación busca identificar los desafíos y oportunidades que presentarán dichos sectores y comenzar a preparar al capital humano para ellos. La metodología utilizada fue un análisis bibliográfico de artículos de frontera, informes de organismos nacionales e internacionales y la plataforma researchrabbit, encontrando que la educación ya se está viendo impactada por la IA y que las empresas a nivel mundial están invirtiendo en ellas. Se considera que se debe comenzar a modificar los procesos educativos para que den respuesta a las necesidades de la industria

    Medición del Aprendizaje en Línea Durante la Pandemia de COVID-19 en Educación Superior en Sinaloa, México: Caso Facultad de Psicología de la Universidad Autónoma de Sinaloa

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    The COVID-19 Pandemic was a global social phenomenon, which in sociological terms is called a phenomenon that can be defined as a “Total Social Fact”, a concept coined by the French sociologist and anthropologist Marcel Mauss (1971), because it disrupts reality to such an extent that human activities are paralyzed. It is in this context that online classes were given, permanently, disrupting student learning and impacting their achievement. Understanding the level of student learning through a digital medium is an important aspect in future events like the one we are facing or for the development of digital teaching platforms themselves.La Pandemia de COVID-19 fue un fenómeno social mundial, lo que en terminos sociologicos se denomina un fenómeno que se puede definir como un “Hecho Social Total”, un concepto acuñado por el sociólogo y antropólogo francés Marcel Mauss (1971), porque trastoca la realidad a tal  punto que se paralizan las actividades humanas. Es en este contexto que se dieron las clases en línea, de forma permanente, trastocando el aprendizaje de los alumnos e impactando en su aprovechamiento. Comprender el nivel de aprendizaje de los alumnos a través de un medio digital es un aspecto importante en futuros sucesos como el que afrontamos o para el propio desarrollo de las plataformas digitales de enseñanza

    Microstructure of an Extruded Third-Generation Snack Made from a Whole Blue Corn and Corn Starch Mixture

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    Blue corn is a potential material for expanded snack production. Whole blue corn meal was mixed with corn starch and processed by extrusion to produce a third-generation snack. Optimum extrusion conditions were calculated with the response surface methodology using expansion index (EI), penetration force (PF), specific mechanical energy (SME) and total anthocyanins content (TAC). Optimum conditions (zone 1, 67°C; cooking zone, 123°C; zone 3, 75°C; feed moisture, 24.6%) were used to extrude the mixture in a single-screw extruder, and EI,PF,SME and TAC of the expanded pellet were compared against predicted optimum values. Starch structural changes in pellets and expanded were analyzed with DSC, viscosity profiles, x-ray diffraction and SEM. Extruded pellet did not differ (p>0.05) from the predicted. However, TAC was lower (p<0.05) in the expanded pellet. Structural analyses showed damage starch granular structure during extrusion and pellet expansion. Blue corn is a promising material for production of third-generation snacks

    Growth Dynamics and Water Potential Components of Three Summer Squash (Cucurbita pepo L.) Cultivars

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    Summer squash fruit is a horticultural crop that possesses a very short postharvest life due to its high rates of metabolism and transpiration along with a low cuticle resistance exhibited mainly when the fruit is harvested at horticultural maturity. This research was realized following the fruit growth of the summer squash cultivars: ‘Enterprise’, ‘Pascola’ and ‘Hurakan F1’, whose seeds were germinated in polystyrene trays and their seedlings were subsequently transferred to pots for optimum growth under greenhouse conditions. Fruits were sampled at 3, 5, 7 and 9 days after anthesis (DAA). Physical (weight, diameter, and length of fruit), chemical (pH, titratable acidity and total soluble solids), hydric status (water, osmotic and pressure potentials), and histological analysis were done. The highest number of fruits having marketing quality were shown in both ‘Pascola’ and ‘Hurakan F1’ cultivars at 7 DAA, whereas, in ‘Enterprise’ was shown at 9 DAA. Marketing quality fruits from the three cultivars showed similarities on pH (about 6.6), titratable acidity (TA) decreases in ‘Enterprise’ and ‘Hurakan F1’, whereas total soluble solids (TSS) decreases in ‘Pascola’ and ‘Hurakan F1’ (pJ 0.5). From 3 to 9 DAA, in all cultivars, the water potential was close to -1.0 MPa, the osmotic potential showed an increasing pattern ranging between -1.59 and -1.15 MPa, and the pressure potential remained in the positive range. Tissue water stability was histologically related to a well-defined parenchyma tissue showing thin-walled, polygonal, intact and turgid cells during fruit growth

    Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

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    Background: Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods: For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings: Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8-13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05-6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50-75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation: Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life

    Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

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    Background Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8–13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05–6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50–75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life. Funding Pfizer, Amgen, Merck Sharp & Dohme, Sanofi–Aventis, Daiichi Sankyo, and Regeneron

    Low exposure long-baseline neutrino oscillation sensitivity of the DUNE experiment

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    The Deep Underground Neutrino Experiment (DUNE) will produce world-leading neutrino oscillation measurements over the lifetime of the experiment. In this work, we explore DUNE's sensitivity to observe charge-parity violation (CPV) in the neutrino sector, and to resolve the mass ordering, for exposures of up to 100 kiloton-megawatt-years (kt-MW-yr). The analysis includes detailed uncertainties on the flux prediction, the neutrino interaction model, and detector effects. We demonstrate that DUNE will be able to unambiguously resolve the neutrino mass ordering at a 3σ\sigma (5σ\sigma) level, with a 66 (100) kt-MW-yr far detector exposure, and has the ability to make strong statements at significantly shorter exposures depending on the true value of other oscillation parameters. We also show that DUNE has the potential to make a robust measurement of CPV at a 3σ\sigma level with a 100 kt-MW-yr exposure for the maximally CP-violating values \delta_{\rm CP}} = \pm\pi/2. Additionally, the dependence of DUNE's sensitivity on the exposure taken in neutrino-enhanced and antineutrino-enhanced running is discussed. An equal fraction of exposure taken in each beam mode is found to be close to optimal when considered over the entire space of interest

    A Gaseous Argon-Based Near Detector to Enhance the Physics Capabilities of DUNE

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    This document presents the concept and physics case for a magnetized gaseous argon-based detector system (ND-GAr) for the Deep Underground Neutrino Experiment (DUNE) Near Detector. This detector system is required in order for DUNE to reach its full physics potential in the measurement of CP violation and in delivering precision measurements of oscillation parameters. In addition to its critical role in the long-baseline oscillation program, ND-GAr will extend the overall physics program of DUNE. The LBNF high-intensity proton beam will provide a large flux of neutrinos that is sampled by ND-GAr, enabling DUNE to discover new particles and search for new interactions and symmetries beyond those predicted in the Standard Model
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