Особливості законодавчого регулювання процесу становлення інформаційного суспільства в Україні у контексті перспектив європейської інтеграції (Involution of Constitutionalism and Quasi-authoritarian Regime in Ukraine)

В статті розкрито особливості, недоліки, перспективи законодавчого регулювання становлення українського інформаційного суспільства (The purpose of research is to characterize special features, deficiencies and perspectives of legislation regularity of the Ukrainian information society

Optimization of plant densities of dolichos (dolichos lablab L. var. lignosus) bean in the Right-bank of Forest-steppe of Ukraine

ArticleThe density of the plants of Dolichos bean significantly influenced the economically valuable indicators, because there is always competition for light, moisture and nutrients between plants in the life process. The period from mass sprouting to the technical ripeness was reduced with increasing the plant density. Such a pattern was characteristic of all phases of the growth and development of the Dolichos bean. The plants with high population (71 thousand units ha-1) took short period (60 and 119 days) from germination to the beginning of technical and biological ripeness, respectively, turned out to be the earliest ripening crops. The plants are better illuminated, the soil nutrition conditions are improved and the sanitary-hygienic climate of the crops improves with thinned crops, thereby plant productivity has raised. However, the average yield of scapulabeans and unripe Dolichos seeds is regulated by the density of the plants, and increased in density due to the greater number of plants. The optimum density for Dolichos bean was 71 thousand plants per hectare, at which yields of green shoots and green peas were formed 7.3 and 3.3 t ha-1, respectively

Studying the storage and processing quality of the carrot taproots (Daucus carota) of various hybrids

This paper presents the results acquired from the study of eight carrot hybrids which are suitable for growing in the climatic zone of woodland steppes, while considering a set of economical and/or biological, biochemical, and organoleptic properties. The carrot hybrids that were studied have a wide range of variation in their economic value indicators, which makes it possible to grow them for storage and processing in various soils and climate conditions without irrigation. The most productive carrot hybrids are White Sabine F1 and Yellowstone F1 with a commercial yield of 55.8–58.7 t hа–1 and an average taproot weight of 118.7–136.2 g. The levels of preservation of the taproot of the hybrids White Sabine F1 and Purple Haze F1 after seven months of storage in conditions that involved the use of a stationary pit storage facility was at 81.4% and 80.2% respectively. The use of the taproots of the hybrids Yellowstone F1 and Viking F1 for drying ensures a yield of a high-quality, biologically-valuable finished product with a yield of 11.4–11.7%. Dry hybrid Evolyutsiya F1 and Mars F1 carrots contain more than 40 mg (100 g)–1 of β-carotene

Suitability of various onion (allium cepa) varieties for drying and long-term storage

Received: April 15th, 2021 ; Accepted: July 21st, 2021 ; Published: July 22nd, 2021 ; Correspondence: [email protected] the paper, the results are presented obtained in the research into the fresh bulbs and the dried products of 9 onion varieties cultivated in the conditions of the Ukrainian Forest Steppe area with regard to their economical biology, biochemical, marketability and organoleptic indices. The varieties that are most suitable for convection drying and long-term storage have been identified. It has been established that the marketability of both the fresh bulbs and dried products depends on the masses of the bulbs. The Bronze d’Amposta and Harmony varieties deliver the greatest amount of marketable output (94.0 and 93.2%) featuring marketable bulbs with masses of 67.4 g and 70.4 g, respectively (r = 0.82). As the bulb mass increases, the amount of non-standard (r = -0.81) and small (r = -0.76) particles in the dried product decreases substantially. It has been found that the content of solid matter and sugars in fresh bulbs has effect on the yield and quality of the dried and reconstituted products. The Harmony and Skvirskaya varieties, the bulbs of which during the vegetation season build up 12.9% and 13.8% of solid matter, respectively, are distinguished by the highest dry product yield - 17.1 and 16.8%, respectively. Correlation has been established between the contents of solid matter and sugars in fresh bulbs (r = + 0.58). During the tasting of reconstituted onion products, the highest scores were awarded to the samples produced from the Skvirskaya and Harmony varieties - 7.0 points each on the 9-point scale, as their bulbs had accumulated over 7.0% of sugars (total). Judging by the aggregate of the researched indices, the Harmony and Skvirskaya varieties of onions are the most suitable for convection drying. It has been established that the preservation of onions in the conditions of stationary buried storage without artificial cooling depends on the duration of storage and the specific varietal features. Within the five months of the test storage, the preservation of bulbs of all the varieties was high and varied within the range of 80–93%. Longer storage is expedient only in case of the Harmony, Skvirskaya and Gospodinya, for which the bulb preservation rates for a seven month storage period has been shown to be equal to 90.2, 88.4 and 87.2%, respectively. It has been proved that the quantity of healthy bulbs depends to a significant extent on the solid matter content in the bulbs (r = 0.93)

Research into properties of blue melilot and fenugreek cultivated using different sowing times

Received: September 6th, 2021 ; Accepted: January 30th, 2022 ; Published: February 17th, 2022 ; Correspondence: [email protected] paper presents the results of the research into the properties of blue melilot (Melilotus caeruleus (L.) Desr.) and fenugreek (Trigonella foenum graecum L.) with regard to the set of their economy-and-biology and biochemical indices in relation to the dates of their sowing. It has been established that the two species under consideration feature wide ranges of index variability depending on the sowing term and the weather conditions. The earliest ripening terms have been recorded for species in case of summer sowing dates (decade I of June), when short growing season lengths of 36–37 days were observed. At the same time, in terms of heavy plant herbage yield obtained from species in the green conveyor system, the early spring (decades II–III of April) and late spring (decade I of May) sowing terms are more suitable providing a herbage yield of 5.7–6.9 t ha–1 in case of blue melilot and 7.3–9.3 t ha–1 for fenugreek, with a solids content of 12.4–28.4%, total sugars of 2.5–5.0% and vitamin C - 38.0–51.8 mg (100 g)-1 . For the purpose of obtaining the spice named ‘Greek hay’ (foenum Graecum), a better choice is to cultivate fenugreek with early spring (decades II–III of April) and late spring (decade I of May) sowing times, as in this case a greater vegetation mass develops, resulting in a plant dry weight yield of 1.3–1.4 t ha–1. An increase in the total precipitation by 1 mm has contributed to the variation of the herbage yield within the range of 15.0 to 77.3 kg ha–1, dry matter yield - 0.693 to 25.9 kg ha–1. High seed yield has been noted in case of sowing the species in early spring (decades II–III of April), where the seed yield of blue melilot was equal to 0.4 t ha-1, fenugreek - 2.0 t ha-1 , their 1,000 seeds having a weight of 0.71 and 9.7 g, respectively

Economics, finance, banking and education: modern challenges and innovations

У збірнику подані тези доповідей за матеріалами VIІ Міжнародної науково-практичної Інтернет-конференції, в яких розглядаються сучасні тренди економічного розвитку в цілому та банківського сектору зокрема. Особливу увагу приділено питанням діджиталіцації у сфері освіти та економіки; а також проблемам впливу розвитку фінансових технологій і цифрових валют на банківську конкуренцію, монетарну політику, фінансову стабільність та підходи до банківського регулювання. Конференція проводиться кафедрою банківської справи Одеського національного економічного університету. Видання розраховане на дослідників, викладачів і студентів економічних спеціальностей, практикуючих фінансистів, юристів, аналітиків, працівників органів державного управління.The materials of the VII International Scientific and Practical Internet Conference are presented in the collection. Modern trends in economic development in general and the banking sector in particular has been considered. Special attention was paid to issues of digitization in the sphere of education and economy; as well as the problems of the impact of the development of financial technologies and digital currencies on banking competition, monetary policy, financial stability and approaches to banking regulation. The conference is held by the Banking Department of the Odesa National University of Economics. The publication is intended for researchers, teachers and students of economic specialties, practicing financiers, lawyers, analysts, and employees of state administration bodies

Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature

BACKGROUND: To identify a diagnostic blood transcriptomic signature that distinguishes multisystem inflammatory syndrome in children (MIS-C) from Kawasaki disease (KD), bacterial infections, and viral infections. METHODS: Children presenting with MIS-C to participating hospitals in the United Kingdom and the European Union between April 2020 and April 2021 were prospectively recruited. Whole-blood RNA Sequencing was performed, contrasting the transcriptomes of children with MIS-C (n = 38) to those from children with KD (n = 136), definite bacterial (DB; n = 188) and viral infections (DV; n = 138). Genes significantly differentially expressed (SDE) between MIS-C and comparator groups were identified. Feature selection was used to identify genes that optimally distinguish MIS-C from other diseases, which were subsequently translated into RT-qPCR assays and evaluated in an independent validation set comprising MIS-C (n = 37), KD (n = 19), DB (n = 56), DV (n = 43), and COVID-19 (n = 39). RESULTS: In the discovery set, 5696 genes were SDE between MIS-C and combined comparator disease groups. Five genes were identified as potential MIS-C diagnostic biomarkers (HSPBAP1, VPS37C, TGFB1, MX2, and TRBV11-2), achieving an AUC of 96.8% (95% CI: 94.6%-98.9%) in the discovery set, and were translated into RT-qPCR assays. The RT-qPCR 5-gene signature achieved an AUC of 93.2% (95% CI: 88.3%-97.7%) in the independent validation set when distinguishing MIS-C from KD, DB, and DV. CONCLUSIONS: MIS-C can be distinguished from KD, DB, and DV groups using a 5-gene blood RNA expression signature. The small number of genes in the signature and good performance in both discovery and validation sets should enable the development of a diagnostic test for MIS-C

HLA B27 allele types in homogeneous groups of juvenile idiopathic arthritis patients in Latvia

Juvenile idiopathic arthritis (JIA) is a heterogeneous condition and therapeutic strategies vary in different JIA types. The routinely accepted practice to start with Sulphasalazine (SS) as the first line treatment in patients with HLA B27 positive JIA proves to be ineffective in a large proportion of children

Genomic investigations of unexplained acute hepatitis in children

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK1. Here we report an investigation of 38 cases, 66 age-matched immunocompetent controls and 21 immunocompromised comparator participants, using a combination of genomic, transcriptomic, proteomic and immunohistochemical methods. We detected high levels of adeno-associated virus 2 (AAV2) DNA in the liver, blood, plasma or stool from 27 of 28 cases. We found low levels of adenovirus (HAdV) and human herpesvirus 6B (HHV-6B) in 23 of 31 and 16 of 23, respectively, of the cases tested. By contrast, AAV2 was infrequently detected and at low titre in the blood or the liver from control children with HAdV, even when profoundly immunosuppressed. AAV2, HAdV and HHV-6 phylogeny excluded the emergence of novel strains in cases. Histological analyses of explanted livers showed enrichment for T cells and B lineage cells. Proteomic comparison of liver tissue from cases and healthy controls identified increased expression of HLA class 2, immunoglobulin variable regions and complement proteins. HAdV and AAV2 proteins were not detected in the livers. Instead, we identified AAV2 DNA complexes reflecting both HAdV-mediated and HHV-6B-mediated replication. We hypothesize that high levels of abnormal AAV2 replication products aided by HAdV and, in severe cases, HHV-6B may have triggered immune-mediated hepatic disease in genetically and immunologically predisposed children

Особливості законодавчого регулювання процесу становлення інформаційного суспільства в Україні в контексті перспектив Європейської інтеграції

У статті розкрито особливості, недоліки, перспективи законодавчого регулювання становлення українського інформаційного суспільства.(The purpose of research is to characterize special features, deficiencies and perspectives of legislation regularity of the Ukrainian information society.