PCl5 as a mild and efficient catalyst for the synthesis of bis(indolyl)methanes and di-bis(indolyl)methanes

Phosphorus pentachloride (PCl5) can efficiently catalyze the condensation of indoles with aldehydes as well as ketones at room temperature to afford bis(indolyl)methanes and di-bis(indolyl)methanes in high yields and short reaction times. KEY WORDS: PCl5, bis(Indolyl)methane, di-bis(Indolyl)methane, Indole, Aldehyde, Ketone  Bull. Chem. Soc. Ethiop. 2008, 22(3), 453-458

Facile preparation of a nanostructured functionalized catalytically active organosalt

We report a novel nanostructured organosalt, based on sulfonic acid functionalized pyrazinium {[H-pyrazine–SO3H]Cl2} that was synthesized and characterized by several techniques including Fourier transform infrared (FT- IR) spectroscopy, X-ray diffraction (XRD), thermal gravimetric analysis (TGA), differential thermal gravimetric (DTG) analysis, transmission electron microscopy (TEM), mass spectrometry (MS), proton NMR (1H NMR), carbon-13 NMR (13C NMR) and also electron diffraction (ED) patterns. Results proved that the unprecedented sulfonated pyrizinium organosalt is indeed nanostructured and highly crystalline as supported by TEM, ED and XRD studies, having an average nanoparticle size of 50 nm according to TEM micrographs. The novel nano- organocatalyst was proved to be an efficient catalyst in the synthesis of 1,2,4,5-tetrasubstituted imidazoles by a one-pot multi-component condensation of benzil, a broad range of aldehydes, primary amines and ammonium acetate at 90 °C under solvent-free conditions

Highly Efficient Synthesis of 1-Thioamidoalkyl-2-naphthols and 14-Aryl-14H-dibenzo[a,j]xanthenes using a Novel Ionic Liquid: Catalyst Preparation, Characterization and Performing the Reactions

In this work, a novel Brønsted acidic ionic liquid namely triethylaminium-N-sulfonic acid trifluoroacetate {[TEASA][TFA]} has been synthesized by the reaction of NEt3 with ClSO3H, and then with CF3CO2H. The ionic liquid has been characterized by studying its spectroscopic data (1H and 13C NMR, FT-IR, and mass spectra). Afterward, it has been utilized as a highly effective and general catalyst to promote the following organic reactions in solvent-free conditions: (i) the production of 1-thioamidoalkyl-2-naphthols from arylaldehydes, 2-naphthol and thioacetamide, and (ii) the preparation of 14-aryl-14H-dibenzo[a,j]xanthenes from arylaldehydes and 2-naphthol. It is noteworthy that [TEASA][TFA] has catalyzed the reactions under milder conditions relative to most of the reported methods. Moreover, it afforded the both products in higher yields with respect to most of the previous works. Copyright © 2018 BCREC Group. All rights reserved Received: 21st June 2017; Revised: 6th October 2017; Accepted: 9th October 2017; Available online:  11st June 2018; Published regularly: 1st August 2018 How to Cite: Saadat, A., Zare, A., Jamadi, F., Abdolalipour-Saretoli, M. (2018). Highly Efficient Synthesis of 1-Thioamidoalkyl-2-naphthols and 14-Aryl-14H-dibenzo[a,j]xanthenes using a Novel Ionic Liquid: Catalyst Preparation, Characterization and Performing the Reactions. Bulletin of Chemical Reaction Engineering & Catalysis, 13 (2): 204-212 (doi:10.9767/bcrec.13.2.1280.204-212

Ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br): a green and neutral reaction media for the efficient, catalyst-free synthesis of quinoxaline derivatives

Quinoxaline derivatives were produced in excellent yields and short reaction times via the condensation of 1,2-diamines with 1,2-diketones in the neutral ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under catalyst-free and microwave irradiation conditions

Diagnostic accuracy of circular RNA for diabetes Mellitus : a systematic review and diagnostic Meta-analysis

Acknowledgements: We thank all our staff at the Tehran University of medical sciences and at Kurdistan University of Medical sciences who helped us in this work. We also acknowledge the papers that we used and participants in those papers. Funding Information: The authors declare that no funds, grants, or other support were received during the preparation of this manuscript. Publisher Copyright: © 2023, The Author(s).Peer reviewedPublisher PD

Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones

Abstract: A highly efficient protocol for the one-pot multi-component condensation of acetophenones with aromatic aldehydes, acetonitrile and acetyl chloride in the presence of melamine trisulfonic acid (MTSA) as a highly efficient and recyclable sulfonic acid-containing catalyst at room temperature is described. In this method, β-acetamido ketone derivatives are obtained in high to excellent yields and in relatively short reaction times

Synthesis, characterization and application of N,N,N',N'-tetramethylethylenediaminium-N-(silica-n-propyl)-N'-sulfonic acid chloride trifluoroacetate as a novel and effective catalyst for preparation of bis-coumarins

In this research, a novel material namely N,N,N',N'-tetramethylethylenediaminium-N-(silica-n-propyl)-N'-sulfonic acid chloride trifluoroacetate ([TEDSPSCT]) was synthesized, and its structure was characterized using Fourier-transform infrared spectroscopy (FT-IR), energy-dispersive X-ray (EDS), field emission scanning electron microscopy (FE-SEM), thermal gravimetric (TG), differential thermal gravimetric (DTG) and x-ray diffraction (XRD); most of the partcles were in nano-size, and a few of them were in micro-size. Afterward, [TEDSPSCT] was used as effective and recyclable catalyst for the preparation of bis-coumarins via the reaction of 4-hydroxycoumarin (2 equivalents) with arylaldehydes (1 equivalent) under solvent-free conditions; these compounds were obtained in high yields and short reaction times. Moreover, an attractive and logical mechanism based on dual-functionality of the catalyst has been described {this catalyst has both acidic group (SO3H) and weak basic group (trifluoroacetate)}

PRODUCTION, CHARACTERIZATION AND USAGE OF A NOVEL DISULFONIC ACID-FUNCTIONALIZED IONIC LIQUID AS A HIGHLY EFFICIENT AND DUAL-FUNCTIONAL CATALYST FOR THE SYNTHESIS OF 1,8-DIOXO-9,10-DIARYL-DECAHYDROACRIDINES

We have produced a novel ionic liquid {N,N,N',N'-tetramethylethylene-diaminium-N,N'-disulfonic acid trifluoroacetate ([TMEDSA][TFA]2)}, and identified it by analysis of 1H NMR, 13C NMR, 19F NMR, mass, TG (thermogravimetry) and DSC (differential scanning calorimetry) data. Then, we have applied [TMEDSA][TFA]2 as a dual-functional catalyst for the production of 1,8-dioxo-9,10-diaryl-decahydroacridines by the multi-component reaction of dimedone with arylaldehydes and primary amines. Furthermore, we have proposed a plausible and attractive mechanism based on dual-functionality of the catalyst. Due to dual-functionality of [TMEDSA][TFA]2 (possessing acidic and basic sites), and also possessing two sites of each, it was highly effective and general, and produced the products in high yields