687 research outputs found

    Patterns of Anxiety and Performative Approaches to Language Learning

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    openStudents experience language learning anxiety, which may make it difficult to use and improve their language; the effects of foreign language Anxiety (FLA) on learners of all ages and competence levels have recently drawn the attention of researchers and educators. Optimizing language learning experiences and results requires an understanding of the causes of FLA, its impacts on language learners, and appropriate mitigation methods. The purpose of this thesis is to explore the concept of language anxiety as described in the literature and how it can influence learners in various contexts. It will go on to investigate the relationship between language anxiety and drama or performative approaches to language learning, and to examine the link between language anxiety and performance of various kinds. Students may be worried when it comes to "performing" in a second or foreign language, and as a result, this may create an "affective filter" which could impede language learning. (Krashen, 1985, p. 81). The purpose of this study is to explore: To what extent a group of learners perceived their language anxiety when undertaking a range of performative activities (in class or as part of a drama group)? How the causes of language anxiety in performative learning may be reduced? Whether performative approaches to language learning might help to reduce language anxiety?Students experience language learning anxiety, which may make it difficult to use and improve their language; the effects of foreign language Anxiety (FLA) on learners of all ages and competence levels have recently drawn the attention of researchers and educators. Optimizing language learning experiences and results requires an understanding of the causes of FLA, its impacts on language learners, and appropriate mitigation methods. The purpose of this thesis is to explore the concept of language anxiety as described in the literature and how it can influence learners in various contexts. It will go on to investigate the relationship between language anxiety and drama or performative approaches to language learning, and to examine the link between language anxiety and performance of various kinds. Students may be worried when it comes to "performing" in a second or foreign language, and as a result, this may create an "affective filter" which could impede language learning. (Krashen, 1985, p. 81). The purpose of this study is to explore: To what extent a group of learners perceived their language anxiety when undertaking a range of performative activities (in class or as part of a drama group)? How the causes of language anxiety in performative learning may be reduced? Whether performative approaches to language learning might help to reduce language anxiety

    Recanalization of the Chronically Occluded Internal Carotid Artery: Review of the Literature.

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    Introduction: We reviewed the literature on interventions for patients with medically refractory chronically occluded internal carotid artery (COICA) to assess the risks and/or benefits after recanalization via an endovascular technique (ET) or hybrid surgery (HS, i.e., ET plus carotid endarterectomy). Methods: A systematic search of the electronic databases was performed. Patients with COICA were classified into 4 different categories according to Hasan et al classification. Results: Eighteen studies satisfied the inclusion criteria. Only 6 studies involved an HS procedure. We identified 389 patients with COICA who underwent ET or HS; 91% were males. The overall perioperative complication rate was 10.1% (95% confidence interval [CI]: 7.4%-13.1%). For types A and B, the successful recanalization rate was 95.4% (95% CI: 86.5%-100%), with a 13.7% (95% CI: 2.3%-27.4%) complication rate. For type C, the success rate for ET was 45.7% (95% CI: 17.8%-70.7%), with a complication rate of 46.0% (95% CI: 20.0%-71.4%) for ET and for the HS technique 87.6% (95% CI: 80.9%-94.4%), with a complication rate of 14.0% (95% CI: 7.0%-21.8%). For type D, the success rate of recanalization was 29.8% (95% CI: 7.8%-52.8%), with a 29.8% (95% CI: 6.1%-56.3%) complication rate. Successful recanalization resulted in a symmetrical perfusion between both cerebral hemispheres, resolution of penumbra, normalization of the mean transit time, and improvement in Montreal Cognitive Assessment (MoCA) score (ΔMoCA = 9.80 points; P = 0.004). Conclusions: Type A and B occlusions benefit from ET, especially in the presence of a large penumbra. Type C occlusions can benefit from HS. Unfortunately, we did not identify an intervention to help patients with type D occlusions. A phase 2b randomized controlled trial is needed to confirm these findings

    Sex Differential in 15-Hydroxyprostaglandin Dehydrogenase Levels in the Lumen of Human Intracranial Aneurysms.

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    BACKGROUND: Aspirin is a promising medical therapy for the prevention of intracranial aneurysm (IA) rupture. Recently, we found that men have a better response to aspirin than women. The purpose of this study was to determine whether a sex differential exists in the level of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in the lumen of human IAs. METHODS AND RESULTS: Consecutive patients undergoing coiling or stent-assisted coiling for a saccular IA at our institution were enrolled. Two samples (A and B) were collected from IA lumens, and the plasma level of 15-PGDH was measured using an ELISA-based method. The study included 38 patients, with 20 women and 18 men. Women and men were comparable on baseline characteristics. The mean plasma concentration of 15-PGDH did not differ statistically between sample A (62.8±16.2 ng/mL) and sample B (61.8±17.9 ng/mL; 95% confidence interval -6.6 to 9.4). The mean plasma concentration of 15-PGDH in IA lumens of samples A and B was significantly higher in men (73.8±13.5 ng/mL) than women (49.6±7.8 ng/mL; P\u3c0.0001). CONCLUSIONS: Higher enzyme levels of 15-PGDH exist in the lumen of IAs of men compared with women. This observation could explain why aspirin confers better protection against IA rupture in men than in women. The susceptibility of an individual to aspirin may differ according to the level of 15-PGDH

    Behavior of corroded bonded fully prestressed and conventional concrete beams

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    AbstractPrestressed concrete is widely used in the construction buildings. And corrosion of steel is one of the most important and prevalent mechanisms of deterioration for concrete structures. Consequently the capacity of post-tension elements decreased after exposure to corrosion. This study presents results of the experimental investigation of the performance/behavior of bonded fully prestressed and conventional concrete beams, with 40MPa compressive strength exposed to corrosion. The experimental program of this study consisted of three fully prestressed and two conventional concrete beams with overall dimensions equal to 150×400×4500mm. The variables were considered in terms of corrosion exposure effect, prestressed level, and corrosion location effect for fully prestressed beams. Mode of failure, cracking width/distribution, ultimate load and the corresponding deflection of each beam were recorded. The results showed that the fully prestressed beam in comparison with conventional beam was considered to be even more resistance to corrosion because it was perceived to be crack-free as a result of prestressing. Also the mention deterioration incident in fully prestressed beams fully corrosion exposure level unnoticed that deterioration incident in partially corrosion exposure level. The most of deterioration incident in fully prestressed beam acts on compression of non-prestressed steel reinforcement. Because the bonded tendons are less likely to corrode. Cement grout/duct is a barrier to moisture and chloride penetration, especially plastic duct without splices. The theoretical analysis based on strain compatibility and force equilibrium gave a good prediction of the deformational behavior for fully prestressed beams

    Focal High Intensity Focused Ultrasound for Prostate Cancer

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    Chapter Bookinfo:eu-repo/semantics/nonPublishe

    International logistic

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    1 online resource (52 leaves) : ill.Includes abstract.Includes bibliographical references (leaf 52).The business case subject of this project is the international trade of a Canadian product in a way to reduce the cost of the logistic system. The goal of the paper is to provide the highest profit per unit of investment. This project consists of an investment which results in spending money either by paying to the suppliers or the cost of the logistic system (Transportation – Inventories). That being said, the analysis should be based on a strategy to control the risk. Creating the logistic system and analyzing it from suppliers to customers in addition to choosing the product and the locations either for the manufactures or the target market are important deliverables of the project. This paper can be used as a guide for international trade. It studies the entire steps necessary to trade a product internationally, from the selection of the product to the assembling of the logistic system and from the Supply/demand concept to the logistic cost calculation. The paper shows how to calculate the cost per item including transportation cost. Also, it shows how to predict the quantity demanded to see if the project breakeven

    Plasma Soluble Human Elastin Fragments as an Intra-Aneurysmal Localized Biomarker for Ruptured Intracranial Aneurysm

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    Background—Fragmentation of the tunica media is a hallmark of intracranial aneurysm formation, often leading to aneurysmal progression and subsequent rupture. The objective of this study is to determine the plasma level of elastin fragments in the lumen of ruptured versus unruptured human intracranial aneurysms. Methods and Results—One hundred consecutive patients with/without ruptured saccular intracranial aneurysms undergoing endovascular coiling or stent-assisted coiling were recruited. Blood samples were collected from the lumen of intracranial aneurysm using a microcatheter. The tip of the microcatheter was placed inside the aneurysm’s sac in close proximity to the inner wall of the dome. Plasma levels of elastin fragments were measured using an ELISA-based method. Mean plasma level of soluble human elastin fragments was significantly greater in ruptured aneurysms when compared with nonruptured aneurysms (102.0±15.5 versus 39.3±9.6 ng/mL; P\u3c0.001). Mean plasma level of soluble human elastin fragments did not have significant correlation with age, sex, size, or aneurysm location. Conclusions—The present study revealed that a significantly higher concentration of soluble human elastin fragments in the lumen of ruptured intracranial aneurysms when compared with nonruptured ones. © 2018 The Authors

    Impacto do programa Juro Zero: aumento na taxa de MEIs nos municípios catarinenses entre 2011 e 2019

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    TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O presente trabalho tem como objetivo avaliar o impacto do incentivo do microcrédito sobre a taxa de participação MEI no mercado de trabalho. Para tanto, analisa mais especificamente o programa Juro Zero com atuação em todos municípios catarinenses, durante o período de 2011 à 2019. Utilizou-se o método de pareamento com escore de propensão por vizinho mais próximo, para construção de um grupo de controle comparável composto pelos municípios paulistas. Em seguida, estima-se o impacto do programa pelo método diferenças em diferenças, utilizando desde sua versão mais básica até a inclusão de mais controles, como covariadas explicativas e efeitos fixos. O impacto se mostrou nulo a 10% de significância. Porém, ao utilizar a base inteira de municípios sem qualquer controle, a taxa MEI de SP cresceu 1,75 p.p., em média, acima dos municípios de SC. A partir do processo adotado, considera-se que não há evidência suficiente para mensurar o impacto do programa. Assim, sugere-se novas pesquisas, modificando os parâmetros na modelagem e adicionando mais estados para compor o grupo de controle

    Cerebral Arteriovenous Malformations: Evaluation and Management.

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    There has been increased detection of incidental AVMs as result of the frequent use of advanced imaging techniques. The natural history of AVM is poorly understood and its management is controversial. This review provides an overview of the epidemiology, pathophysiology, natural history, clinical presentation, diagnosis, and management of AVMs. The authors discussed the imaging techniques available for detecting AVMs with regard to the advantages and disadvantages of each imaging modality. Furthermore, this review paper discusses the factors that must be considered for the most appropriate management strategy (based on the current evidence in the literature) and the risks and benefits of each management option

    Plasma and intracellular (platelet) zinc levels in chronic renal failure (CRF) patients under different treatment modalities

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    The causes and degree of zinc (Zn) deficiency in uraemia are still controversial. The effect of different treatment modalities are still unsettled. Plasma Zn represents only a small part of the total body Zn (about 0.5%). Thus determination of intracellular Zn in the peripheral blood cells might be more reliable. The present study was designed to assess the actual Zn status in uraemia and to find whether the treatment modalities of CRF (conservative and dialytic) could influence Zn status. Also to determine the elfeet of single dialysis session, type of dialysis and dialysate buffer on the Zn status.This study included ten healthy controls and fourty CRF patients divided in three subgroups on different treatment modalities (10 conservative treatment, 15 on intermittent perioneal dialysis ((IPD) and 15 on haemedialysis (HD). Zinc was measured by atomic absorption spectrophotometry in plasma and platelets. Statistically significant decrease of plasma Zn and significant increase of platelet Zn were found in CRF patients on different treatment modalities as compared to controls (P<0.01), but there was no significant difference in this respect hetween the three uraemic subgroups. There was no difference as regard serum protein and albunun levels in uraemic subgroups compared to controls. Moreover plasma Zn was significantly increased (still less than control) and platelet Zn was significantly decreased (P<0.01) after a single dialysis session in both IPD and HD subgroups, but the changes of both parameters (before and after dialysis) were insignificant in IPD patients compared to HD patients.Significant negative correlation was found between platelet Zn and creatinine clearance in the three uraemic subgroups (r = -0.81 P<0.01 in conservative patients, r= -0.72 P<0.01 in IPD and r= -0.76 P<0.01 in HD) while no correlation could be detected between the duration of dialysis and each of platelet & plasma Zn and between plasma Zn and each of platelet Zn, serum creatinine and clearance. Plasma Zn showed transient significant rise in HD patients using bicarbonate (11.6 ± 1.1 umol/L) as compared to those using acetate buffer (9.1 ± 1.3 umol/L), P<0.01. We can conclude that intracellular measurements of Zn (platelet) is of value in diagnosis and monitoring of Zn status in uraemics. Different treatment modalities does not influence Zn haernostasis. with no superiority of particular type of dialysis in this respect. The effect of a single dialysis session and the use of bicarbonate versus acetate buffer was just a transient rise of plasma Zn due to haemoconcentration and better correction of acidosis during dialysis
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