355 research outputs found

    SISTEM INFORMASI GEOGRAFIS PEMETAAN POTENSI PERTAMBANGAN KABUPATEN SUMBAWA

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    Geographic Information System or GIS is a computer-based information system to store, manage, analyze, and retrieve geographically referenced data. By utilizing GIS, it will make it easier for users or decision makers to determine the policies taken, especially those related to spatial aspects or what is also called spatial. The purpose of this research is (i) Processing data and presenting data results using webgis with CodeIgniter and Qgis frameworks. Learning about webgis using CodeIgniter and Qgis frameworks. (ii) Building a Geographic Information System for mapping the mining potential in Sumbawa Regency based on WebGIS. The research method used is Waterfall. resulted in a Geographic Information System for Mapping the Mining Potential of Sumbawa Regency. The Mining Potential of Sumbawa Regency is 161 mines. The majority are Sand Mines with a total of 48 mines and a minority of Petroleum Mines with a total of 3 mines

    PENGARUH PENGGUNAAN KAMUS BERGAMBAR BAHASA MANDARIN TERHADAP PENGUASAAN KOSAKATA BAHASA MANDARIN PADA SISWA KELAS X SMK NEGERI 1 BRONDONG LAMONGAN

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    Kata Kunci : kosakata, Mandarin, kamus bergambar bahasa Mandarin Dalam mempelajari suatu bahasa mutlak diperlukan penguasaan kosakata untuk menunjang kemampuan berbahasa. Kosakata mempunyai peranan penting dalam kemampuan berbahasa karena muncul dalam setiap keterampilan berbahasa karena merupakan salah satu aspek kebahasaan yang harus diperhatikan dan dikuasai, guna menunjang kelancaran berkomunikasi dengan bahsa Mandarin, baik dalam ragam lisan maupun ragam tulisan. Didalam bahsa Mandarin, kosakta disebut cihui词汇. Didalam bahasa Mandarin terdapat jenis pembagian kosakata yaitu kata benda名词(mingci), kata kerja 动词(dongci), dan kata sifat形容词(xingrongci). Mengingat pentingnya penguasaan kosakata bahasa Mandarin, peranan guru sebagai pendidik dan pengajar harus bisa memotivasi siswa dalam pembelajaran bahasa Mandarin, jadi guru harus bisa mempersiapkan media yang bersifat menarik dan inovatif. Maka dari itu agar pembelajaran dapat berjalan dengan baik dan tidak membosankan perlu adanya suatu media dalam mengajar. Salah satu media yang dapat digunakan adalah media kamus bergambar Bahasa Mandarin yang dapat digunakan dengan mudah dalam pembelajaran. Tujuan dari penelitian ini adalah 1) menjelaskan penggunaan kamus bergambar bahasa Mandarin dalam pembelajaran kosakata bahasa Mandarin pada siswa kelas X SMK Negeri 1 Brondong Lamongan tahun ajaran 2015/2016. 2) mendeskripsikan pengaruh penggunaan kamus bergambar bahasa Mandarin pada siswa kelas X SMK Negeri 1 Brondong Lmongan tahun ajaran 2015/2016. 3) mendeskripsikan respon siswa terhadap penggunaan kamus bergambar bahasa Mandarin siswa kelas X SMK Negeri 1 Brondong Lamongan. Penelitian ini merupakan penelitian eksperimen dengan menggunakan metode kuantitatif yang bersifat deskriptif. Penelitian ini berlangsung empat kali pertemuan. Dua kali dikelas kontrol dengan menggunakan metode ceramah dan dua kali dikelas eksperimen dengan menggunakan media kamus bergambar bahasa Mandarin. Dalam hal ini tatacara dalam penggunaan kamus bergambar bahasa Mandarin adalah Pada kegiatan awal siswa diberikan pre test terlebih dahulu untuk mengetahui penguasaan kosakata siswa sebelum diberi pengajaran menggunakan media. Kemudian Pada kegiatan awal peneliti membentuk beberapa kelompok kecil yang terdiri dari 5-6 orang, kemudian setelah itu peneliti membagikan kamus bergambar bahasa mandarin. Setiap kelompok diberi satu kamus bergambar bahasa mandarin. Setelah itu peneliti membahas salah satu topik dari kamus bergambar bahasa mandarin, topik yang akan dibahas adalah tentang makanan dan buah-buahan yaitu pada bab 3. Kegiatan selanjutnya yaitu memberikan permainan. Permainan yang digunakan adalah permainan tebak gambar, pada permainan tebak gambar ini peneliti memberikan soal yang berupa gambar yang ditampilkan pada slide power point. Lalu semua siswa diminta meriview apa yag telah diajarkan peneliti sebelumnya, kemudian diberikan soal post test. Hasil penelitian dengan menggunakan media kamus bergambar bahasa Mandarin dapat diketahui hasil analisis data yang dilakukan, diperoleh harga = 3,27 dan = 44 selanjutnya dikonsultasikan dengan melihat nilai tabel taraf 5%. Dengan harga = 3,27 dan = 44 maka diketahui bahwa ts = 0,05 = 2,00 t lebih besar dari t tabel (3,27>2,00). Harga mengalami signifikansi. Maka dapat disimpulkan bahwa penggunaan kamus bergambar bahasa Mandarin mempunyai pengaruh yang signifikansi terhadapa kelas eksperimen yaitu kelas X Multimedia SMK Negeri 1 Brondong Lamongan. Berdasarkan hasil angket penggunaan media kamus bergambar bahasa Mandarin pada kelas eksperimen bahwa 88% dengan menggunakan kamus bergambar bahasa Mandarin, siswa lebih dapat mengerti makna kosakata bahasa Mandarin, dan 88% dengan menggunakan kamus bergambar bahasa Mandarin siswa dapat mengingat dan menghafal kosakta dengan mudah. Keywords: vocabulary, Mandarin, Mandarin language picture dictionary In learning a language is absolutely necessary vocabulary to support proficiency. Vocabulary play an important role in the ability to speak to appear in every language skills because it is one of the aspects of language that must be considered and controlled, in order to support smooth communication with Mandarin language support, both in a variety of oral and written language. In the Mandari language support, vocabulary called 词汇 whoopee. In Mandarin there is the sharing type of vocabulary that is, nouns 名词 (mingci), verb 动词 (dongci), and the adjective 形容词 (xingrongci). Given the importance of Mandarin vocabulary, the role of teachers as educators and teachers should be able to motivate students in learning the Mandarin language, so teachers should be able to prepare the media that is both interesting and innovative. Therefore for learning to work well and not boring needs to be a media in teaching. One medium that can be used is the picture dictionary Mandarin media that can be used easily in learning. The purpose of this study were 1) to explain the use of a picture dictionary in learning Mandarin vocabulary in class X SMK Negeri 1 Lamongan Brondong academic year 2015/2016. 2) describe the effect of the use of a picture dictionary Mandarin in class X SMK Negeri 1 Brondong Lamongan the academic year 2015/2016. 3) describe the students'''' response to the use of a picture dictionary Mandarin class X SMK Negeri 1 Lamongan Brondong academic year 2015/2016. This study was an experimental study using quantitative descriptive method. The study lasted four meetings. Twice in class control by using the lecture method and twice in class experiments using a picture dictionary Mandarin media. In this case the procedure in the use of pictorial dictionary Mandarin is In the initial activity students were given pre-test beforehand to determine students'''' mastery of vocabulary before teaching by using the media. Then In the early activities of researchers form several small groups of 5-6 people, then after that researchers share a picture dictionary mandarin. Each group was given a picture dictionary mandarin. After the researchers discuss one of the topics of a picture dictionary mandarin, a topic that will be discussed is about the food and fruit that is in Chapter 3. The next activity is to give the game. Used games is a game of guessing the picture, the picture guessing game about which researchers provide an image displayed on a power point slide. Then all the students asked what it has taught meriview previous researchers, then given a post-test questions. The results using a picture dictionary Mandarin media can be seen the results of data analysis, obtained price = 3.27 and = 44 further consulted with seeing the value table level of 5%. With the price of = 3.27 and = 44 it is known that ts = 0.05 = 2.00 t greater than t table (3.27> 2.00). Prices have significance. It can be concluded that the use of a picture dictionary Mandarin has significant influence terhadapa experimental class is class X Multimedia SMK Negeri 1 Lamongan Brondong. Based on the results of questionnaires use a picture dictionary Mandarin media the experimental class that 88% by using a picture dictionary Mandarin, students better understand the meaning of the vocabulary of Mandarin, and 88% by using a picture dictionary Mandarin students can remember and memorize vocabulary easily

    Klasifikasi Fasies pada Reservoir Menggunakan Crossplot Data Log P-Wave dan Data Log Density

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    Klasifikasi fasies merupakan salah satu cara untuk menentukan jenis batuan dari data well log. Telah dilakukan klasifikasi fasies pada reservoir untuk mengetahui persebaran properti dan fasiesnya. Metode yang digunakan ialah crossplot antara data log p-wave dengan data log density. Kontrol dilakukan dengan menggunakan data log gamma ray, log neutron, log porositas dan data core. Data fasies diklasifikasikan menjadi 4, yaitu Super Sandy Globigerina sebagai limestone berpori tinggi sebagai reservoir, Sandy Globigerina sebagai limestone yang didominasi oleh sand, Shaly Globigerina sebagai limestone yang didominasi oleh shale serta Compact Globigerina merupakan limestone kompak tanpa pori

    SRT1720 attenuates obesity and insulin resistance but not liver damage in the offspring due to maternal and postnatal high-fat diet consumption

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    © 2018 the American Physiological Society. Recent studies indicate that sirtuin-1 (SIRT1), an important metabolic sensor and regulator of life span, plays a mechanistic role in maternal obesity-induced programming of metabolic disorders in the offspring. In this study we investigate whether SIRT1 activation in early childhood can mitigate metabolic disorders due to maternal and postnatal high-fat feeding in mice. Male offspring born to chow-fed (MC) or high fat diet-fed dams (MHF) were weaned onto postnatal chow or high-fat diet and treated with SRT1720 (25 mg/kg ip every 2 days) or vehicle control for 6 wk and examined for metabolic disorders. MHF exacerbated offspring body weight and insulin resistance in the offspring exposed to postnatal HFD (OHF). These metabolic changes were associated with reduced hepatic lipid droplet accumulation but increased plasma levels of alanine aminotransferase (ALT), a marker of liver damage. SRT1720 significantly decreased offspring body weight, adiposity, glucose intolerance, and hyperleptinemia due to OHF and reversed hyperinsulinemia and adipocyte hypertrophy due to the additive effects of MHF. Although SRT1720 suppresses liver lipogenesis, inflammation, and oxidative stress markers, it also reduces antioxidants and increased liver collagen deposition in OHF offspring independent of MHF. Hepatic steatosis was attenuated only in MC/OHF offspring in association with elevated plasma ALT levels. The study suggests that postnatal SRT1720 administration can mitigate obesity and insulin resistance in the offspring due to maternal and postnatal HFD exposure. However, the possibility of liver toxicity needs to be further examined

    The Pattern of Women's Reliance on Family Planning Providers in Egypt

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    Understanding choice of family planning provider is fundamental for policy makers and program managers as they seek ways to both improve the coverage and increase the sustainability and efficiency of family planning services for Egypt to achieve its population objectives. This study focuses first on providing a descriptive profile of the patterns of reliance on sources of family planning services during the early 2000s. Binomial logit models are then estimated to obtain a more in depth understanding of the determinants of the choice of family planning providers in Egypt using the 2000 Egypt Demographic and Health Survey. The study offers insights into a number of aspects of family planning service provision about which there has been less previous investigation. There are marked differences in the extent to which Egyptian women rely on public or private providers for family planning services depending on the type of method they are seeking. Among the more important findings is the consistency women display in the choice of provider among women reporting multiple segments of use. With regard to the determinants of the choice of provider for family planning services, perhaps the most interesting finding is that household wealth was not a significant determinant of the choice of provider. This may reflect that private sources met the demand for family planning services of significant proportions of women in rural areas and among those in the low income groups

    FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity

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    © 2015 Glastras et al. Background: Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offspring to chronic kidney disease (CKD). We aimed to determine whether the nuclear Farnesoid X receptor (FXR), known to play a role in maintaining homeostasis of glucose and lipid metabolism, is involved in renal injury in offspring of obese mothers. Methods: Maternal obesity was established in a rat model by feeding dams with high-fat diet prior to and during pregnancy and lactation. The offspring's kidneys were examined at postnatal Day 1and Day 20. Human kidney 2 (HK2) cells were exposed to high glucose with or without the FXR agonist GW4064 or when FXR mRNA was silenced. Results: Glucose intolerance in the offspring of obese mothers was evident at weaning, with associated downregulation of renal FXR expression and upregulation of monocyte chemoattractant protein-1 (MCP-1) and transforming growth factor-β1 (TGF-β1). HK2 cells exposed to high glucose had reduced FXR expression and increased MCP-1, TGF-β1, fibronectin and collagen IV expression, which was reversed in the presence of GW4064. FXR-silenced HK2 cells had amplified pro-inflammatory and pro-fibrotic markers under high glucose conditions. Conclusions: Maternal obesity influences renal expression of pro-inflammatory and fibrotic factors that predispose the offspring to CKD. This was associated with the downregulation of the renal FXR expression suggesting a potential protective role for FXR

    Sirt1 attenuates kidney disorders in male offspring due to maternal high-fat diet

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    © 2019, MDPI AG. All rights reserved. Maternal obesity has been associated with kidney disorders in male offspring. Our previous studies have demonstrated that Sirtuin (SIRT)1, an essential regulator of metabolic stress responses, is suppressed in the offspring as the result of maternal high-fat diet (HFD) consumption, which is likely to underpin the adverse metabolic and renal outcomes. To examine if SIRT1 overexpression or activation early in life can protect the offspring kidney, wild-type (WT) and transgenic (Tg) offspring were born to the same diet-induced obese female C57BL/6 mice through breeding with hemizygous SIRT1-transgenic (Tg) male mice and examined for renal pathological changes. In separate experiments, SIRT1 activator SRT1720 (25 mg/kg/2 days i.p) was administrated in WT offspring over 6 weeks of postnatal high-fat diet exposure. The results show that offspring born to obese dams have increased kidney weight, higher levels of renal triglycerides, and increased expression of oxidative stress, inflammatory, and fibrotic markers, as well as increased albuminuria compared to offspring of control dams. Both SIRT1 overexpression and SRT1720 treatment attenuated renal lipid contents and expression of lipogenesis, oxidative stress, and inflammatory markers; however, fibrosis was modestly reduced and albuminuria was not affected. The findings suggest that SIRT1 therapy can ameliorate some pathological mechanisms of kidney programming due to maternal obesity but may not be sufficient to prevent the resulting chronic kidney injury

    Maternal L-carnitine supplementation ameliorates renal underdevelopment and epigenetic changes in male mice offspring due to maternal smoking

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    © 2018 John Wiley & Sons Australia, Ltd Objectives: Epidemiological and animal studies showed that L-carnitine (LC) supplementation can ameliorate oxidative stress-induced tissues damage. We have previously shown that maternal cigarette smoke exposure (SE) can increase renal oxidative stress in newborn offspring with postnatal kidney underdevelopment and renal dysfunction in adulthood, which were normalised by LC administration in the SE dams during pregnancy. Exposure to an adverse intrauterine environment may lead to alteration in the epigenome, a mechanism by which adverse prenatal conditions increase the susceptibility to chronic disease later in life. The current study aimed to determine whether maternal SE induces epigenetic changes in the offspring's kidney are associated with renal underdevelopment, and the protective effect of maternal LC supplementation. Method: Female Balb/c mice (7 weeks) were exposed to cigarette smoke (SE) or air (Sham) for 6 weeks prior to mating, during gestation and lactation. A subgroup of the SE dams received LC via drinking water (SE + LC, 1.5 mmol/L) throughout gestation and lactation. Male offspring were studied at postnatal day (P)1, P20, and 13 weeks. Results: Maternal SE altered the expression of renal development markers glial cell line-derived neurotrophic factor and fibroblast growth factor 2, which were associated with increased renal global DNA methylation and DNA methyltransferase 1 mRNA expression at birth. These disorders were reversed by maternal LC administration. Conclusion: The effect of maternal SE on renal underdevelopment involves global epigenetic alterations from birth, which can be prevented by maternal LC supplementation

    Maternal Obesity Promotes Diabetic Nephropathy in Rodent Offspring

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    Maternal obesity is known to increase the risk of obesity and diabetes in offspring. Though diabetes is a key risk factor for the development of chronic kidney disease (CKD), the relationship between maternal obesity and CKD has not been clearly defined. In this study, a mouse model of maternal obesity was employed to determine the impact of maternal obesity on development of diabetic nephropathy in offspring. Female C57BL/6 mice were fed high-fat diet (HFD) for six weeks prior to mating, during gestation and lactation. Male offspring were weaned to normal chow diet. At postnatal Week 8, offspring were randomly administered low dose streptozotocin (STZ, 55 mg/kg/day for five days) to induce diabetes. Assessment of renal damage took place at postnatal Week 32. We found that offspring of obese mothers had increased renal fibrosis, inflammation and oxidative stress. Importantly, offspring exposed to maternal obesity had increased susceptibility to renal damage when an additional insult, such as STZ-induced diabetes, was imposed. Specifically, renal inflammation and oxidative stress induced by diabetes was augmented by maternal obesity. Our findings suggest that developmental programming induced by maternal obesity has implications for renal health in offspring. Maternal obesity should be considered a risk factor for CKD

    The role of inflammation modulation in dental pulp regeneration

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    A vital and healthy dental pulp (DP) is required for teeth to remain functional throughout a lifespan . Appreciating its value for the tooth, the regeneration of the DP is a highly researched goal. While inflammation of the DP marks the beginning of an eventual necrosis, it is also the prerequisite for the regenerative events of neovascularisation, stem cells mobilisation and reparative dentine deposition. In the light of a pro-regenerative inflammatory process, the present review discusses the role of macrophage population shift from pro- to anti-inflammatory in reversible versus irreversible pulpitis, while also analysing the overlooked contribution of pulp innervation and locally derived neuropeptides to the process. Then, the currently practiced (pulp capping and revascularisation) and researched (cells transplantation and cell homing) approaches for DP regeneration are discussed. Focusing on the role of cell homing in modulating inflammation, some potential strategies are highlighted to harness the inflammatory process for DP regeneration, mainly by reversing inflammation through macrophage induction. Next, some potential clinical applications are discussed – especially with capping materials – that could boost macrophage polarisation and complement system activation. Finally, current challenges facing the regeneration of the DP are presented, while underlining the importance of promoting an anti-inflammatory environment conducive to a regenerative process
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