Organically modified nanoclay filled thin-film nanocomposite membranes for reverse osmosis application

This study validates, for the first time, the effectiveness of two nanoclays, that is, cloisite (CS)-15A and montmorillonite (MNT) at the polyamide (PA) active layer in the reverse osmosis (RO) membrane. Cloisite-15A is natural montmorillonite modified with dimethyl dihydrogenated tallow quaternary ammonium salt. Thin-film composite (TFC) membranes were fabricated by the interfacial polymerization (IP) process between the trimesoylchloride (TMC)–n-hexane solution and m-phenylenediamine (MPD)–aqueous solution; the IP process took place on a polysulfone support sheet. The two types of nanoparticles were added in various weight ratios (0.005 wt.%–0.04 wt.%) in the n-hexane solution of TMC. Different characterizations like X-ray diffraction (XRD), contact angle, transmission electron microscopy (TEM), and membrane performance tests were performed to analyse the membrane properties. Both XRD and TEM studies proved that the two nanoclays are successfully anchored at the different sites of the PA layer. CS-15A could accelerate the water flux from 15 to 18.65 L/m2·h with NaCl rejection enhancement from 72% to 80%, relative to the control membrane. Conversely, MNT also enhanced the flux from 15 to 40 L/m2·h, but NaCl rejection reduced from 70% to 23%. The mechanism of water uptake in nanoclays was also discussed. The results pave the way for a complete future study, in which these phenomena should be studied in great detail.This research was funded by Qatar University, grant number IRCC-2019-004.The authors would like to acknowledge the support of Qatar University through project number IRCC-2019-004. Also, the authors acknowledge the assistance granted by KACST through the National Science, Technology, and Innovation Plan (NSTIP) unit of King Fahd University of Petroleum and Minerals (KFUPM) through NSTIP research grant number 08WAT-80-4. The assistance in membrane preparation by Matsuura group, Ottawa University, Canada and Rasel Das, Kyushu University Japan for discussion on the results are highly appreciated.Scopu

Cancer Patterns in Karachi Division (1998-1999)

Objective: A minimal cancer incidence data for Karachi, the largest city of Pakistan, is being presented here, for the years 1998-1999. The city has a population of 9,802,134; males 5,261,712 (52.6%) and females 4,540,422 (47.4%); census 19981. Methodology: A predominantly mixed (passive and active) registration system has evolved in Karachi, the data sources being the hospitals within the Karachi Division. The reported/retrieved cancer data sets at the Karachi Cancer Registry are checked, coded, computerised in an analytical format and analysed. Results: The incident cancer cases registered in Karachi, during the 2-year period, 1st January 1998 to 31st December 1999 were analysed. The age-standardised incidence rate (ASR) of cancer, all sites was 132.4/100,000 for the males. Cancer of the lung 10.8%; ASR 17.3 was the most frequently recorded malignancy, followed by oral cavity 10.5%; ASR 13.2 and larynx 5.0%; ASR 7.4. The age-standardised incidence rate (ASR) of cancer, all sites was 133.0/100,000 in the females. Cancer of the breast, 32.0%; ASR 40.7 was the most frequently recorded malignancy, followed by oral cavity 8.1%; ASR 11.7 and gall bladder 3.6%; ASR 5.5. Conclusion: The present data has been calculated with an estimated 15-20% probable under ascertainment. Tobacco-associated cancers in Karachi were responsible for 38.3% of the tumours diagnosed amongst the males. Two principal cancers, breast and oral cavity were responsible for 40.1% of the cancers in females. A rare finding was the high incidence of gall bladder cancer in the females. At present it is difficult to determine whether this indicates a genuine high risk or a selection bias. A continuous process of cancer registration to study the trends in the incidence and an adequate cancer control program are possible and essential for Pakistan and can be based on the pattern being practiced in Karachi

A study of frequency and pulses for stepper motor controller system by using programmable logic controller

The stepper motor movement process produced different frequency and pulses. This research explained about the frequency and pulses for the stepper motor movement by using Programmable Logic Controller (PLC) as research method. The study was done to find the suitable frequency and pulses for stepper motor movement by developing a prototype stepper motor controller system. The pulse frequency used did not affected the distance of moving load in the stepper motor operations. The increasing number of pulse frequency only will affect the time taken for the stepper motor to complete its operations. The result showed that number of pulse frequency at high operation was 5000 Hz. Pulse number reacted as a manipulated variable that affected both factor which is time taken of stepper motor operation and the distance of moving load

Numerical investigation on flame propagation in vented gas explosion

Explosion venting technology is one of the effective and widely used methods in protection measures against accidental internal gas explosions by relieving the pressure generated within the volume. Extensive studies have been carried out to investigate factors governing to the explosion development i.e. ignition position and vent burst pressure. However, the physical and dynamic process of explosion development during the venting to ambient air is yet not well understood. The primary motivation of this research was to gain improved understanding of turbulent flame propagation in vented gas explosion, with a view to develop improved models and methods for assessing explosion risks in the process industries. Computational Fluid Dynamic (CFD) analyses using FLUENT is adopted to study the phenomenology underlying vented gas explosions. Computations were run on deflagrating turbulent flames in small-scale combustion chambers with two different volumes (0.02 m3 and 0.0065 m3), with both closed at the rear end and open at the opposite face, in order to replicate the experimental work. All cases are initialised from stagnation. Only stoichiometric concentration of propane and methane-Air mixtures was considered with different ignition positions and vent static burst pressure, Pv. From the finding, end ignition gave higher reduced overpressure on both experimental and simulation results, compared to central ignition. The inclusion of vents in the enclosures provides significant reduction on the peak overpressures. However, it has been recognised on a tendency to a less effective reduction as the vent burst pressure, Pv was further increased. The competition between combustion rate and venting rate allows the explanation on both number and intensity of the overpressure peaks observed in propane-Air explosion

Casimir effect due to a single boundary as a manifestation of the Weyl problem

The Casimir self-energy of a boundary is ultraviolet-divergent. In many cases the divergences can be eliminated by methods such as zeta-function regularization or through physical arguments (ultraviolet transparency of the boundary would provide a cutoff). Using the example of a massless scalar field theory with a single Dirichlet boundary we explore the relationship between such approaches, with the goal of better understanding the origin of the divergences. We are guided by the insight due to Dowker and Kennedy (1978) and Deutsch and Candelas (1979), that the divergences represent measurable effects that can be interpreted with the aid of the theory of the asymptotic distribution of eigenvalues of the Laplacian discussed by Weyl. In many cases the Casimir self-energy is the sum of cutoff-dependent (Weyl) terms having geometrical origin, and an "intrinsic" term that is independent of the cutoff. The Weyl terms make a measurable contribution to the physical situation even when regularization methods succeed in isolating the intrinsic part. Regularization methods fail when the Weyl terms and intrinsic parts of the Casimir effect cannot be clearly separated. Specifically, we demonstrate that the Casimir self-energy of a smooth boundary in two dimensions is a sum of two Weyl terms (exhibiting quadratic and logarithmic cutoff dependence), a geometrical term that is independent of cutoff, and a non-geometrical intrinsic term. As by-products we resolve the puzzle of the divergent Casimir force on a ring and correct the sign of the coefficient of linear tension of the Dirichlet line predicted in earlier treatments.Comment: 13 pages, 1 figure, minor changes to the text, extra references added, version to be published in J. Phys.

Abnormal ECG Findings in Athletes: Clinical Evaluation and Considerations.

PURPOSE OF REVIEW: Pre-participation cardiovascular evaluation with electrocardiography is normal practice for most sporting bodies. Awareness about sudden cardiac death in athletes and recognizing how screening can help identify vulnerable athletes have empowered different sporting disciplines to invest in the wellbeing of their athletes. RECENT FINDINGS: Discerning physiological electrical alterations due to athletic training from those representing cardiac pathology may be challenging. The mode of investigation of affected athletes is dependent on the electrical anomaly and the disease(s) in question. This review will highlight specific pathological ECG patterns that warrant assessment and surveillance, together with an in-depth review of the recommended algorithm for evaluation

Novel geometrical concept of a high-performance brain PET scanner. Principle, design and performance estimates

We present the principle, a possible implementation and performance estimates of a novel geometrical concept for a high-resolution positron emission tomograph. The concept, which can be for example implemented in a brain PET device, promises to lead to an essentially parallax-free 3D image reconstruction with excellent spatial resolution and constrast, uniform over the complete field of view. The key components are matrices of long axially oriented scintillator crystals which are read out at both extremities by segmented Hybrid Photon Detectors. We discuss the relevant design considerations for a 3D axial PET camera module, motivate parameter and material choices, and estimate its performance in terms of spatial and energy resolution. We support these estimates by Monte Carlo simulations and in some cases by first experimental results. From the performance of a camera module, we extrapolate to the reconstruction resolution of a 3D axial PET scanner in a semi-analytical way and compare it to an existing state-of-the art brain PET device. We finally describe a dedicated data acquisition system, capable to fully exploit the advantages of the proposed concept. We conclude that the proposed 3D axial concept and the discussed implementation is a competitive approach for high-resolution brain PET. Excellent energy resolution and Compton enhanced sensitivity are expected to lead to high-quality reconstruction and reduced scanning times

Epidemiological analysis of typhoid fever in Kelantan from a retrieved registry

Aim: Despite the endemicity of typhoid in Kelantan, epidemiological data showing typhoid association to age, sex,ethnicity and district of patients is limited. This retrospective study investigated the statistical association of thesevariables from a retrieved registry.Methodology and results: Cross-tabulation using SPSS was used to analyze 1394 cases of confirmed typhoid patientsadmitted to various hospitals in Kelantan state over a six-year period. Fourteen age groups with a five-year rangeinterval were generated. There was a significant association between typhoid infection and sex of subjects, wherebyfemales were generally more susceptible than males. Ethnicity and district of typhoid patients did not show significantassociation.Conclusion, significance and impact of study: The observation of an increased number of typhoid cases with a malepredominance in the age group 5-14 and female predominance in the 20-60 age group calls for improved hygiene,continued public health education, together with better laboratory diagnostics to identify carriers, are some measures tocontrol this disease

Neutrino emission via the plasma process in a magnetized plasma

Neutrino emission via the plasma process using the vertex formalism for QED in a strongly magnetized plasma is considered. A new vertex function is introduced to include the axial vector part of the weak interaction. Our results are compared with previous calculations, and the effect of the axial vector coupling on neutrino emission is discussed. The contribution from the axial vector coupling can be of the same order as or greater than the vector vector coupling under certain plasma conditions.Comment: 20 pages, 3 figure

Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology

Pharmacological inhibitors of cysteine proteases have provideduseful insights into the regulation of calpain activity inerythrocytes. However, the precise biological function of calpainactivity in erythrocytes remains poorly understood. Erythrocytesexpress calpain-1, an isoform regulated by calpastatin, theendogenous inhibitor of calpains. In the present study, weinvestigated the function of calpain-1 in mature erythrocytes usingour calpain-1-null [KO (knockout)] mouse model. The calpain-1gene deletion results in improved erythrocyte deformabilitywithout any measurable effect on erythrocyte lifespan in vivo.The calcium-induced sphero-echinocyte shape transition iscompromised in the KO erythrocytes. Erythrocyte membraneproteins ankyrin, band 3, protein 4.1R, adducin and dematin aredegraded in the calcium-loaded normal erythrocytes but not inthe KO erythrocytes. In contrast, the integrity of spectrin andits state of phosphorylation are not affected in the calciumloadederythrocytes of either genotype. To assess the functionalconsequences of attenuated cytoskeletal remodelling in the KOerythrocytes, the activity of major membrane transporters wasmeasured. The activity of the K+\u2013Cl 12 co-transporter and theGardos channel was significantly reduced in the KO erythrocytes.Similarly, the basal activity of the calcium pump was reducedin the absence of calmodulin in the KO erythrocyte membrane.Interestingly, the calmodulin-stimulated calcium pump activitywas significantly elevated in the KO erythrocytes, implying awider range of pump regulation by calcium and calmodulin. Takentogether, and with the atomic force microscopy of the skeletalnetwork, the results of the present study provide the first evidencefor the physiological function of calpain-1 in erythrocytes withtherapeutic implications for calcium imbalance pathologies suchas sickle cell disease