Sustainable Delivery of Speech-Language Therapy Services in Small Island Developing States Using Information and Communication Technology – A Study of the Maldives

Small Island Developing States (SIDS), a subgroup of Majority world countries, face complex challenges providing equitable access to speech-language therapy (SLT) services. Increasing use of information and communication technology (ICT) to enhance SLT services is seen in the Minority world. This study explored the potential of using ICT to provide sustainable SLT services in one SIDS, the Maldives. A mixed method approach was used integrating data from (a) 21 online documents, (b) interview with an ICT official, and (c) surveys of 13 island councillors and 73 parents of children with communication difficulties. Almost 100% of the population had access to mobile phones and mobile broadband internet. Most parents were active and frequent ICT users. The government provided financial aid for people with disabilities which could be utilised to access ICT for services. Asynchronous service delivery using accessible ICT and parents as agents of service delivery can potentially enhance SLT services

Differential Biofeedback Intervention In Moderating Inhibited Performance In Soccer

Performance excellence in soccer crucially depends on mental toughness or more specifically the aspect of emotional flexibility and hardiness of the player. Since indices of projective evaluations can reveal hidden emotional crises and internal conflicts, psychobiological evaluations could substantiate with the inner emotionality revealed to provide etiological information related to performance hindrances in soccer. Present study was carried out to identify the efficacy of skin conductance (Sc) biofeedback in regulation of sudomotor nerve activity (SNA) and of electromyography (EMG) biofeedback in regulation of peak torque and maximal voluntary contraction (MVC) in modification of performance catastrophe in soccer. All of them were assessed with autonomic measures (SNA and Sc amplitude); electromyography evaluation of emotionality and MVC revealed through EMG. Forty National-selection group soccer players of Malaysia were randomly categorized into four groups (Gr. A, N = 10, no-intervention control group); Gr. B (who received Sc biofeedback training); Gr. C (received EMG biofeedback intervention) and Gr. D (players who received combined training of Sc and EMG biofeedback intervention). Players of intervention groups received their respective trainings for 12 weeks (15 min.s /day for 3 days/ week). Postintervention analyses revealed marked improvement in the soccer players who received Sc and EMG biofeedback intervention, and the combined biofeedback training was evident as most efficient intervention technique in modulating emotionality as well as muscle potentiality. Analysis of variance and repeated measure of ANOVA were done to observe shared aetiology in the form of direct, inverse and supportive relationships between psychobiological and emotional indices related to performance crises in soccer. Comprehensive understanding of the confounding relationships between subjective feelings emotionality and corroborative psychobiological indices as predictor of high performance was achieved

Understanding the Broadband Emission Process of 3C 279 through Longterm Spectral Analysis

The long term broadband spectral study of Flat Spectrum Radio Quasars during different flux states has the potential to infer the emission mechanisms and the cause of spectral variations. To scrutinize this, we performed a detailed broadband spectral analysis of 3C 279 using simultaneous Swift-XRT/UVOT and Fermi-LAT observations spanning from August 2008 to June 2022. We also supplement this with the simultaneous NuSTAR observations of the source. The optical/UV, X-ray, and gamma-ray spectra were individually fitted by a power-law to study the long-term variation in the flux and the spectral indices. A combined spectral fit of simultaneous optical/UV and X-ray spectra was also performed to obtain the transition energy at which the spectral energy distribution is minimum. The correlation analysis suggests that the long-term spectral variations of the source are mainly associated with the variations in the low energy index and the break energy of the broken power-law electron distribution which is responsible for the broadband emission. The flux distribution of the source represents a log-normal variability while the gamma-ray flux distribution showed a clear double log-normal behavior. The spectral index distributions were again normal except for gamma-ray which showed a double-Gaussian behavior. This indicates that the log-normal variability of the source may be associated with the normal variations in the spectral index. The broadband spectral fit of the source using synchrotron and inverse Compton processes indicates different emission processes are active at optical/UV, X-ray, and gamma-ray energies.Comment: Accepted in MNRAS on 6th October 202

Weakly Nonlinear Analysis of Electroconvection in a Suspended Fluid Film

It has been experimentally observed that weakly conducting suspended films of smectic liquid crystals undergo electroconvection when subjected to a large enough potential difference. The resulting counter-rotating vortices form a very simple convection pattern and exhibit a variety of interesting nonlinear effects. The linear stability problem for this system has recently been solved. The convection mechanism, which involves charge separation at the free surfaces of the film, is applicable to any sufficiently two-dimensional fluid. In this paper, we derive an amplitude equation which describes the weakly nonlinear regime, by starting from the basic electrohydrodynamic equations. This regime has been the subject of several recent experimental studies. The lowest order amplitude equation we derive is of the Ginzburg-Landau form, and describes a forward bifurcation as is observed experimentally. The coefficients of the amplitude equation are calculated and compared with the values independently deduced from the linear stability calculation.Comment: 26 pages, 2 included eps figures, submitted to Phys Rev E. For more information, see http://mobydick.physics.utoronto.c

Electroconvection in a Suspended Fluid Film: A Linear Stability Analysis

A suspended fluid film with two free surfaces convects when a sufficiently large voltage is applied across it. We present a linear stability analysis for this system. The forces driving convection are due to the interaction of the applied electric field with space charge which develops near the free surfaces. Our analysis is similar to that for the two-dimensional B\'enard problem, but with important differences due to coupling between the charge distribution and the field. We find the neutral stability boundary of a dimensionless control parameter ${\cal R}$ as a function of the dimensionless wave number ${\kappa}$. ${\cal R}$, which is proportional to the square of the applied voltage, is analogous to the Rayleigh number. The critical values ${{\cal R}_c}$ and ${\kappa_c}$ are found from the minimum of the stability boundary, and its curvature at the minimum gives the correlation length ${\xi_0}$. The characteristic time scale ${\tau_0}$, which depends on a second dimensionless parameter ${\cal P}$, analogous to the Prandtl number, is determined from the linear growth rate near onset. ${\xi_0}$ and ${\tau_0}$ are coefficients in the Ginzburg-Landau amplitude equation which describes the flow pattern near onset in this system. We compare our results to recent experiments.Comment: 36 pages, 7 included eps figures, submitted to Phys Rev E. For more info, see http://mobydick.physics.utoronto.ca

ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase

Metastatic colonization involves paracrine/juxtacrine interactions with the microenvironment inducing an adaptive response through transcriptional regulation. However, the identities of transcription factors (TFs) induced by the metastatic microenvironment in ovarian cancer (OC) and their mechanism of action is poorly understood. Using an organotypic 3D culture model recapitulating the early events of metastasis, we identified ETS1 as the most upregulated member of the ETS family of TFs in metastasizing OC cells as they interacted with the microenvironment. ETS1 was regulated by p44/42 MAP kinase signaling activated in the OC cells interacting with mesothelial cells at the metastatic site. Human OC tumors had increased expression of ETS1, which predicted poor prognosis. ETS1 regulated OC metastasis both in vitro and in mouse xenografts. A combination of ChIP-seq and RNA-seq analysis and functional rescue experiments revealed FAK as the key transcriptional target and downstream effector of ETS1. Taken together, our results indicate that ETS1 is an essential transcription factor induced in OC cells by the microenvironment, which promotes metastatic colonization though the transcriptional upregulation of its target FAK

Off the rails: the cost performance of infrastructure rail projects

YesGovernments in Australia place great emphasis on the development and expansion of their rail networks to improve productivity and service the increasing needs and demands from businesses and commuters. A case study approach is used to analyze the cost performance of 16 rail projects constructed by a contractor between 2011 and 2014, which ranged from AU$3.4 to AU$353 million. Findings indicate that scope changes during construction were the key contributors that lead to the amendment of each project’s original contractual value. As a result, there is a need for public and private sector asset owners to establish a cost contingency using a probabilistic rather than a deterministic approach to accommodate the potential for scope changes during construction. To improve cost certainty during the construction of rail projects, it is suggested that use of collaborative forms of procurement juxtaposed with the use of Building Information Modelling and Systems Information Modelling are implemented. The utilization of such technological and process innovations can provide public and private sector asset owners charged with delivering and maintaining their rail networks with confidence projects can be delivered within budget and are resilient to unexpected events and adaptable to changing needs, uses or capacities.The authors would like to acknowledge the financial support provided by the Australian Research Council (DP160102882)

Annular electroconvection with shear

We report experiments on convection driven by a radial electrical force in suspended annular smectic A liquid crystal films. In the absence of an externally imposed azimuthal shear, a stationary one-dimensional (1D) pattern consisting of symmetric vortex pairs is formed via a supercritical transition at the onset of convection. Shearing reduces the symmetries of the base state and produces a traveling 1D pattern whose basic periodic unit is a pair of asymmetric vortices. For a sufficiently large shear, the primary bifurcation changes from supercritical to subcritical. We describe measurements of the resulting hysteresis as a function of the shear at radius ratio $\eta \sim 0.8$. This simple pattern forming system has an unusual combination of symmetries and control parameters and should be amenable to quantitative theoretical analysis.Comment: 12 preprint pages, 3 figures in 2 parts each. For more info, see http://mobydick.physics.utoronto.c