14 research outputs found

    Optimizing intrusion detection in 5G networks using dimensionality reduction techniques

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    The proliferation of internet of things (IoT) technologies has expanded the user base of the internet, but it has also exposed users to increased cyber threats. Intrusion detection systems (IDSs) play a vital role in safeguarding against cybercrimes by enabling early threat response. This research uniquely centers on the critical dimensionality aspects of wireless datasets. This study focuses on the intricate interplay between feature dimensionality and intrusion detection systems. We rely on the renowned IEEE 802.11 security-oriented AWID3 dataset to implement our experiments since AWID was the first dataset created from wireless network traffic and has been developed into AWID3 by capturing and studying traces of a wide variety of attacks sent into the IEEE 802.1X extensible authentication protocol (EAP) environment. This research unfolds in three distinct phases, each strategically designed to enhance the efficacy of our framework, using multi-nominal class, multi-numeric class, and binary class. The best accuracy achieved was 99% in the three phases, while the lowest accuracy was 89.1%, 60%, and 86.7% for the three phases consecutively. These results offer a comprehensive understanding of the intricate relationship between wireless dataset dimensionality and intrusion detection effectiveness

    Role of the triad of procalcitonin, C-reactive protein, and white blood cell count in the prediction of anastomotic leak following colorectal resections

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    Purpose: The enhanced recovery after surgery (ERAS) program expedites patient recovery after major surgery. This study aimed to investigate the role of the triad of procalcitonin (PCT), C-reactive protein (CRP), and white blood cells (WBC) trajectories as a predictive biomarker for the anastomotic leak (AL) after colorectal surgery. Method: Patients who had colorectal anastomosis were prospectively included. Postoperative clinical and laboratory parameters and outcomes were collected and analyzed. The 5-day trajectories of PCT, CRP, and WBC were evaluated. Based on the trajectory of the three biomarkers, we compared patients with and without AL as detected during the first 30 days after surgery using the area under receiver operator characteristic curves (AUC) for logistic estimation. Results: This study included 205 patients, of whom 56% were men and 43.9% were women with a mean age of 56.4 ± 13.1 years. Twenty-two patients (10.7%) had AL; 77.3% underwent surgery, and 22.7% were treated with drainage and antibiotics. Procalcitonin was the best predictor for AL compared to CRP and WBC at three days postoperatively (AUC: 0.84, 0.76, 0.66, respectively). On day 5, a cutoff value of 4.93 ng/mL for PCT had the highest sensitivity, specificity, and negative predictive value. The predictive power of PCT was substantially improved when combined with either CRP or WBC, or both (AUC: 0.92, 0.92, 0.93, respectively). Conclusion: The 5-day trajectories of combined CRP, PCT, and WBC had a better predictive power for AL than the isolated daily measurements. Combining the three parameters may be a reliable predictor of early patient discharge, which would be highly beneficial to ERAS programs

    The role of antioxidants and zinc in minimal hepatic encephalopathy: a randomized trial

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    Background: Minimal hepatic encephalopathy (MHE) has a far-reaching impact on quality and function ability in daily life and may progress to overt hepatic encephalopathy. There is a synergistic effect between systemic oxidative stress and ammonia that is implicated in the pathogenesis of hepatic encephalopathy. The aim of this study is to investigate the effectiveness of oral supplementation of antioxidants and zinc gluconate on MHE versus lactulose. Methods: Our study included 58 patients with cirrhosis diagnosed as having MHE by neuropsychometric tests, including number connection test part A (NCT-A), digit symbol test (DST) and block design tests (BDTs). Patients were randomized to receive 175 mg zinc gluconate, 50,000 IU vitamin A, 500 mg vitamin C and 100 mg vitamin E once daily plus lactulose, dose 30–60 ml/day for 3 months [group A ( n = 31)] or initiated and maintained on lactulose dose 30–60 ml/day for 3 months [group B ( n = 27)]. Neuropsychometric tests and laboratory investigations were repeated after 3 months of therapy. Results: Compared with the baseline neuropsychometric tests, a significant improvement was reported in patients with MHE after 3 months of antioxidant and zinc therapy (group A) versus patients with lactulose therapy (group B) (NCT-A, p < 0.001; DST, p = 0.006; BDT, p < 0.001). Antioxidant and zinc supplementation significantly decreased arterial ammonia level, alanine aminotransferase (ALT), aspartate aminotransferase (AST) ( p < 0.001) and improved Child–Pugh score in MHE after 3 months of therapy ( p = 0.024). Conclusion: Antioxidant and zinc supplementation can improve MHE in patients with liver cirrhosis
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