3D Object Recognition with Keypoint Based Algorithms

Object recognition is important in many practical applications of computer vision. Traditional 2D methods are negatively affected by illumination, shadowing and viewpoint. 3D methods have the potential to solve these problems, because 3D models include geometric properties of the objects. In this paper, 3D local feature based algorithms were used for 3D object recognition. The local feature was keypoint. This study aimed to research facilities of keypoints for 3D object recognition. Keypoint is feature of object that is detected by detector algorithms according to certain mathematical base. A recognition system was designed. For this purpose, a database that includes 3D model of objects was created. The algorithms were improved in MATLAB. The keypoints on the 3D models were detected using keypoint detectors. These keypoints were described by keypoints descriptors. The descriptor algorithms detect geometrical relation between each point of point cloud and create a histogram. In the third step, the keypoints in different point clouds are matched using the feature histograms obtained. Statistical methods are used to compare generated histograms. Thus, the two closest similar points between the different point clouds are matched. It is expected that the models with the most corresponding points belong to the same object. Euclidean distance between corresponding keypoints in the two point cloud is calculated. It has been accepted that the points are shorter than 10 mm. The positional accuracy of the matched points has been examined. Iterative Closest Point (ICP) was applied to the matching point clouds for this purpose. As a result, the graphics were generated that showed correct matching ratio and root mean square error. As a result, there are different approaches about 3D object recognition in literature. This study aimed to compare different keypoint detector and descriptor algorithms. Intrinsic Shape Signature (ISS) is keypoint detector algorithms. Point Feature Histograms (PFH) and Fast Point Feature Histograms (FPFH) are keypoint descriptor algorithms. The results of this study will provide guidance for future studies

Effect of zinc sulfate on common cold in children: Randomized, double blind study

WOS: 000251253100010PubMed ID: 18045283Background: The aim of the present randomized, double-blind, placebo-controlled study was to determine the efficacy of zinc sulfate on the duration and severity of common cold in children. Methods: Children presenting at least two of 10 symptoms of common cold within the 24-48 h of the onset of illness were eligible for the study. Children were randomized to receive either oral zinc containing zinc sulfate or placebo. A diary was completed to record symptoms and adverse effects. Symptoms were scored as absent (0), mild (1), moderate (2), or severe (3). Results: One hundred and fifty children participated in the study, and 120 children were included in the final analysis. The median duration of all cold symptoms was 6 days (P = 0.20), and the median duration of nasal symptoms was 5 days in both groups (P = 0.09). However, total symptom severity scores were significantly lower in the zinc group, starting from the second day of the study. The lower scores in the zinc group were largely due to improvement of nasal symptom scores. Adverse effects were similar in both groups. Conclusion: Zinc sulfate had no effect on the duration of cold symptoms. However, it appears to be effective in reducing the severity of the cold symptoms in healthy children

Von Hippel-Lindau Disease: The Importance of Retinal Hemangioblastomas in Diagnosis

Von Hippel-Lindau (VHL) hastalığı birden fazla sistemi ilgilendiren selim veya habis tümörlerle karakterize ailesel kanser sendromudur. Retinal hemanjiyoblastomlar genellikle hastalığın ilk bulgusu olup görme kaybına neden olabilmektedirler. Otuz iki yaşında erkek hasta sol gözünde 2 aydır olan görme kaybı nedeniyle kliniğimize başvurdu. Hastanın serebral hemanjiyoblastom nedeniyle daha önce opere olduğu, soygeçmişinde annesinin bir gözünde ileri görme kaybı bulunduğu ve böbrek kanseri nedeniyle kaybedildiği öğrenildi. Olgunun oftalmolojik muayenesinde her iki gözde çok sayıda retinal hemanjiyoblastomlar görüldü. Hastaya VHL gen dizi analizi yapıldı ve heterozigot p.R161X mutasyonu saptandı. Hastanın kız kardeşinde ve kızında da aynı mutasyon belirlendi. Hasta ve etkilenmiş aile bireyleri için izlem ve tedavi planı düzenlendi. Retinal hemanjiyoblastomların ayırıcı tanısında VHL hastalığının düşünülmesi bu hastalarda görülen hayatı tehdit eden tümörlerin erken saptanmasında önemli bir yere sahiptir.Von Hippel-Lindau (VHL) disease is a familial cancer syndrome characterized by benign or malignant tumors which may involve more than one system. Retinal hemangioblastomas are usually the initial manifestation of VHL disease and can cause vision loss. A 32-yearold man presented to our clinic with vision loss in the left eye for 2 months. He had a history of cerebral hemangioblastoma operation. Family history showed that his mother had unilateral vision loss and died because of renal cell carcinoma. Ophthalmologic examination revealed multiple retinal hemangioblastomas in both eyes. VHL gene sequencing was performed and heterozygous p.R161X mutation was detected. His sister and daughter were also found to have the same variant. A treatment and follow-up plan was initiated for the patient and affected family members. Considering VHL disease in the differential diagnosis of retinal hemangioblastomas has a very important role in the early detection of life-threatening tumors in these patients

Von Hippel-Lindau Hastalığı: Retinal Hemanjiyoblastomların Tanıdaki Önemi

Von Hippel-Lindau (VHL) disease is a familial cancer syndrome characterized by benign or malignant tumors which may involve more than one system. Retinal hemangioblastomas are usually the initial manifestation of VHL disease and can cause vision loss. A 32-yearold man presented to our clinic with vision loss in the left eye for 2 months. He had a history of cerebral hemangioblastoma operation. Family history showed that his mother had unilateral vision loss and died because of renal cell carcinoma. Ophthalmologic examination revealed multiple retinal hemangioblastomas in both eyes. VHL gene sequencing was performed and heterozygous p.R161X mutation was detected. His sister and daughter were also found to have the same variant. A treatment and follow-up plan was initiated for the patient and affected family members. Considering VHL disease in the differential diagnosis of retinal hemangioblastomas has a very important role in the early detection of life-threatening tumors in these patients.Von Hippel-Lindau (VHL) hastalığı birden fazla sistemi ilgilendiren selim veya habis tümörlerle karakterize ailesel kanser sendromudur. Retinal hemanjiyoblastomlar genellikle hastalığın ilk bulgusu olup görme kaybına neden olabilmektedirler. Otuz iki yaşında erkek hasta sol gözünde 2 aydır olan görme kaybı nedeniyle kliniğimize başvurdu. Hastanın serebral hemanjiyoblastom nedeniyle daha önce opere olduğu, soygeçmişinde annesinin bir gözünde ileri görme kaybı bulunduğu ve böbrek kanseri nedeniyle kaybedildiği öğrenildi. Olgunun oftalmolojik muayenesinde her iki gözde çok sayıda retinal hemanjiyoblastomlar görüldü. Hastaya VHL gen dizi analizi yapıldı ve heterozigot p.R161X mutasyonu saptandı. Hastanın kız kardeşinde ve kızında da aynı mutasyon belirlendi. Hasta ve etkilenmiş aile bireyleri için izlem ve tedavi planı düzenlendi. Retinal hemanjiyoblastomların ayırıcı tanısında VHL hastalığının düşünülmesi bu hastalarda görülen hayatı tehdit eden tümörlerin erken saptanmasında önemli bir yere sahiptir

Von Hippel-Lindau Disease: the Importance of Retinal Hemangioblastomas in Diagnosis

Von Hippel-Lindau (VHL) hastalığı birden fazla sistemi ilgilendiren selim veya habis tümörlerle karakterize ailesel kanser sendromudur. Retinal hemanjiyoblastomlar genellikle hastalığın ilk bulgusu olup görme kaybına neden olabilmektedirler. Otuz iki yaşında erkek hasta sol gözünde 2 aydır olan görme kaybı nedeniyle kliniğimize başvurdu. Hastanın serebral hemanjiyoblastom nedeniyle daha önce opere olduğu, soygeçmişinde annesinin bir gözünde ileri görme kaybı bulunduğu ve böbrek kanseri nedeniyle kaybedildiği öğrenildi. Olgunun oftalmolojik muayenesinde her iki gözde çok sayıda retinal hemanjiyoblastomlar görüldü. Hastaya VHL gen dizi analizi yapıldı ve heterozigot p.R161X mutasyonu saptandı. Hastanın kız kardeşinde ve kızında da aynı mutasyon belirlendi. Hasta ve etkilenmiş aile bireyleri için izlem ve tedavi planı düzenlendi. Retinal hemanjiyoblastomların ayırıcı tanısında VHL hastalığının düşünülmesi bu hastalarda görülen hayatı tehdit eden tümörlerin erken saptanmasında önemli bir yere sahiptir.Von Hippel-Lindau (VHL) disease is a familial cancer syndrome characterized by benign or malignant tumors which may involve more than one system. Retinal hemangioblastomas are usually the initial manifestation of VHL disease and can cause vision loss. A 32-year- old man presented to our clinic with vision loss in the left eye for 2 months. He had a history of cerebral hemangioblastoma operation. Family history showed that his mother had unilateral vision loss and died because of renal cell carcinoma. Ophthalmologic examination revealed multiple retinal hemangioblastomas in both eyes. VHL gene sequencing was performed and heterozygous p.R161X mutation was detected. His sister and daughter were also found to have the same variant. A treatment and follow-up plan was initiated for the patient and affected family members. Considering VHL disease in the differential diagnosis of retinal hemangioblastomas has a very important role in the early detection of life-threatening tumors in these patients

Factor 8 Gene Mutation Spectrum of 270 Patients with Hemophilia A: Identification of 36 Novel Mutations

Objective: Hemophilia A (HA) is the most severe X-linked inherited bleeding disorder caused by hemizygous mutations in the factor 8 (F8) gene. The aim of this study is to determine the mutation spectrum of the F8 gene in a large HA cohort from Turkey, and then to establish a phenotype-genotype correlation

Clinical features of generalized lipodystrophy in Turkey: A cohort analysis

Aim: To describe the Turkish generalized lipodystrophy (GL) cohort with the frequency of each complication and the death rate during the period of the follow-up. Methods: This study reports on 72 patients with GL (47 families) registered at different centres in Turkey that cover all regions of the country. The mean ± SD follow-up was 86 ± 78 months. Results: The Kaplan–Meier estimate of the median time to diagnosis of diabetes and/or prediabetes was 16 years. Hyperglycaemia was not controlled in 37 of 45 patients (82.2%) with diabetes. Hypertriglyceridaemia developed in 65 patients (90.3%). The Kaplan–Meier estimate of the median time to diagnosis of hypertriglyceridaemia was 14 years. Hypertriglyceridaemia was severe (≥ 500 mg/dl) in 38 patients (52.8%). Seven (9.7%) patients suffered from pancreatitis. The Kaplan–Meier estimate of the median time to diagnosis of hepatic steatosis was 15 years. Liver disease progressed to cirrhosis in nine patients (12.5%). Liver disease was more severe in congenital lipodystrophy type 2 (CGL2). Proteinuric chronic kidney disease (CKD) developed in 32 patients (44.4%) and cardiac disease in 23 patients (31.9%). Kaplan–Meier estimates of the median time to diagnosis of CKD and cardiac disease were 25 and 45 years, respectively. Females appeared to have a more severe metabolic disease, with an earlier onset of metabolic abnormalities. Ten patients died during the follow-up period. Causes of death were end-stage renal disease, sepsis (because of recurrent intestinal perforations, coronavirus disease, diabetic foot infection and following coronary artery bypass graft surgery), myocardial infarction, heart failure because of dilated cardiomyopathy, stroke, liver complications and angiosarcoma. Conclusions: Standard treatment approaches have only a limited impact and do not prevent the development of severe metabolic abnormalities and early onset of organ complications in GL