34 research outputs found
(E)-Methyl 2-[(2S,3S,12bR)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyacrylate ethanol solvate
In the title compound, C23H30N2O4·C2H6O, the indole derivative has four fused rings, forming an indolo[2-3a]quinolizine system, in which one six-membered ring is directly connected to the indole unit and has a distorted chair conformation. The fourth ring is also a six-membered ring, depicting a regular chair conformation. In the crystal, the molecules are linked by N—H⋯O and O—H⋯N interactions, forming a C(7) chain
Acta Cirúrgica Brasileira -Vol
. Scientific, intellectual, conception and design of the study, critical revision. ABSTRACT PURPOSE: To evaluate the occurrence of seroma and surgical wound infection after surgery. METHODS: A total of 42 individuals with large incisional hernias were subjected to onlay mesh repair. Following the mesh placement, the participants were randomly allocated to two groups. In group 1, closed-suction drains were placed in the subcutaneous tissue, while progressive tension sutures were performed in group 2. The participants were subjected to clinical and ultrasound assessment to detect seroma and surgical wound infection at three time-points after surgery. RESULTS: The occurrence of seroma at the early, intermediate or late assessments was respectively 19.0%, 47.6%, 52.4% in group 1 and 28.6%, 57.1%, 42.9% in group 2 and was not significantly different between groups (p 0.469; 0.631; 0.619). Surgical wound infection occurred 19% in group 1 and 23.8% in group 2, without a significant difference between the groups (p>0.999). CONCLUSION: The frequency of seroma and infection did not exhibit significant differences between individuals subjected to onlay mesh repair of large incisional hernias with drains or progressive tension sutures without drainage
Modeling Kepler transit light curves as false positives: Rejection of blend scenarios for Kepler-9, and validation of Kepler-9d, a super-Earth-size planet in a multiple system
Light curves from the Kepler Mission contain valuable information on the
nature of the phenomena producing the transit-like signals. To assist in
exploring the possibility that they are due to an astrophysical false positive,
we describe a procedure (BLENDER) to model the photometry in terms of a "blend"
rather than a planet orbiting a star. A blend may consist of a background or
foreground eclipsing binary (or star-planet pair) whose eclipses are attenuated
by the light of the candidate and possibly other stars within the photometric
aperture. We apply BLENDER to the case of Kepler-9, a target harboring two
previously confirmed Saturn-size planets (Kepler-9b and Kepler-9c) showing
transit timing variations, and an additional shallower signal with a 1.59-day
period suggesting the presence of a super-Earth-size planet. Using BLENDER
together with constraints from other follow-up observations we are able to rule
out all blends for the two deeper signals, and provide independent validation
of their planetary nature. For the shallower signal we rule out a large
fraction of the false positives that might mimic the transits. The false alarm
rate for remaining blends depends in part (and inversely) on the unknown
frequency of small-size planets. Based on several realistic estimates of this
frequency we conclude with very high confidence that this small signal is due
to a super-Earth-size planet (Kepler-9d) in a multiple system, rather than a
false positive. The radius is determined to be 1.64 (+0.19/-0.14) R(Earth), and
current spectroscopic observations are as yet insufficient to establish its
mass.Comment: 20 pages in emulateapj format, including 8 tables and 16 figures. To
appear in ApJ, 1 January 2010. Accepted versio