From Incunabula to Book History: Ethiopia, Eritrea and the Search for their Printed Past

The history of the printed book in Africa is a relatively new line of inquiry. One of the most challenging issues confronting its practitioners will be to produce authoritative and comprehensive records of the national output of African countries, an essential prerequisite before venturing into more complex analysis. In this panorama, Eritrea and Ethiopia seem to represent two happy exceptions: the pioneering work of Ḫǝruy Wäldä Śǝllase, Stephen Wright’s Ethiopian Incunabula and then the supplements by Stefan Strelcyn, Osvaldo Raineri, and Kibrom Tseggai have allowed for the reconstruction of large sections of the print production of the two countries. This article maps out the cultural and political context in which the attention for Ethiopian incunabula emerged and traces the stages of the collective effort that has allowed the preservation of the traces of the early printed documentation in Eritrea and Ethiopia. The article argues that there are still significant margins of improvement in the retrospective coverage of the history of the printed book in Africa, especially since the arrival of digital technologies and the Internet that have offered a very effective set of tools for solving some of the problems that have plagued African retrospective national bibliographies since their inception

DEVELOPING NEW APPROACHES TO THE PRESERVATION AND SHARING OF AFRICA’S PRINTED HERITAGE: THE ERITREAN CASE.

The project that we have been working in the last two years is the case of a dispersed collection and the attempt to virtually recreate/ reassemble it. The project was financed by the European Union (EU) with the granting of a Marie Curie fellowship and implemented in cooperation with the Research and Documentation Centre of Asmara and the University of Pavia (Italy) in the period 2009-2011

Outcome of acute type A aortic dissection: single-center experience from 1998 to 2007

Introduction. Acute aortic dissection (AAD) is a serious disease of the aorta with high mortality and morbidity, which requires emergency surgical treatment in order to close the site of the dissection and direct blood flow into the true lumen. Improvements in surgical technique have led to better management of patients with reduced operative mortality, although it still remains high. The aim of this study is to evaluate early and late outcomes of the surgical treatment of acute type A aortic dissection at the hospital of Lecce between 1998 and 2007. We also aim to establish a correlation between these outcomes and pre-operative conditions, surgical procedures and location of the site of the tear. Methods. From 1998 to 2007, 100 patients (69 males and 31 females, average age 62.2 ? 12.3 years, range 22-85 years) underwent surgery for acute AAD at the center. Surgical techniques included replacement of the ascending aorta (Asc Ao) with or without valve replacement (including five patients who underwent the Bentall/De Bono procedure) and replacement of the Asc Ao with or without arch or hemiarch replacement. Results. In-hospital mortality was 22%, with different results between surgery for replacement of the aorta and for aorta with valve replacement (respectively, 16% and 23%). Different mortality rates were found between the distal surgical treatments, with rates of 20.8% and 18.2% respectively between replacements of the Asc Ao and of Asc Ao with arch/hemiarch, although they were not statistically significant. A different mortality rate that was subject to the patient\u27s preoperative condition has also been found (33.3% of mortality in patients in unstable or highrisk condition vs 13.8% in patients in stable condition). The peak reached 43.5% mortality in patients taken to the operating room while in shock or cardiac tamponade. The location of the site of the tear is another factor that distinguishes mortality rates, which are 17.8% if localized at the proximal ascending aorta and 22.2% in the aortic arch. Assessment of the outcome (10 years after surgery), has shown that four patients died several years later but for reasons unrelated to the surgery. Conclusions. The surgery of dissection is still an intervention with a relatively high in-hospital mortality risk, and whose outcome, which has been steady in the last 20 years, can be predicted according to the preoperative condition of the patient. This underlines the need to reduce the time of diagnosis indicating immediate surgical treatment

Menadione-induced oxidative stress re-shapes the oxylipin profile of Aspergillus flavus and its lifestyle

Aspergillus flavus is an efficient producer of mycotoxins, particularly aflatoxin B1, probably the most hepatocarcinogenic naturally-occurring compound. Although the inducing agents of toxin synthesis are not unanimously identified, there is evidence that oxidative stress is one of the main actors in play. In our study, we use menadione, a quinone extensively implemented in studies on ROS response in animal cells, for causing stress to A. flavus. For uncovering the molecular determinants that drive A. flavus in challenging oxidative stress conditions, we have evaluated a wide spectrum of several different parameters, ranging from metabolic (ROS and oxylipin profile) to transcriptional analysis (RNA-seq). There emerges a scenario in which A. flavus activates several metabolic processes under oxidative stress conditions for limiting the ROS-associated detrimental effects, as well as for triggering adaptive and escape strategies

Physical activity measured by implanted devices predicts atrial arrhythmias and patient outcome: Results of IMPLANTED (Italian Multicentre Observational Registry on Patients With Implantable Devices Remotely Monitored)

Background--To determine whether daily physical activity (PA), as measured by implanted devices (through accelerometer sensor), was related to the risk of developing atrial arrhythmias during long-term follow-up in a population of heart failure (HF) patients with an implantable cardioverter defibrillator (ICD). Methods and Results--The study population was divided into 2 equally sized groups (PA cutoff point: 3.5 h/d) according to their mean daily PA recorded by the device during the 30- to 60-day period post-ICD implantation. Propensity score matching was used to compare 2 equally sized cohorts with similar characteristics between lower and higher activity patients. The primary end point was time free from the first atrial high-rate episode (AHRE) of duration 656 minutes. Secondary end points were: first AHRE 656 hours, first AHRE 6548 hours, and a combined end point of death or HF hospitalization. Data from 770 patients (65\ub115 years; 66% men; left ventricular ejection fraction 35\ub112%) remotely monitored for a median of 25 months were analyzed. A PA =3.5 h/d was associated with a 38% relative reduction in the risk of AHRE 656 minutes (72-month cumulative survival: 75.0% versus 68.1%; log rank P=0.025), and with a reduction in the risk of AHRE 656 hours, AHRE 6548 hours, and the combined end point of death or HF hospitalization (all P < 0.05). Conclusions--In HF patients with ICD, a low level of daily PA was associated with a higher risk of atrial arrhythmias, regardless of the patients' baseline characteristics. In addition, a lower daily PA predicted death or HF hospitalization

ABSTRACTS OF PRESENTATIONS

Second International Conference on African Digital Libraries and Archives, abstracts of presentation

Introduction

This book aims to suggest an analysis of the conflict that focuses on three crucial points. The first is related to space. It is now evident that the framework of the nation-state is too circumscribed and does not capture the complexity of the relations that came into being at local, national and international levels. In this regard, we find particularly penalising the conventional approach that tends to investigate WWI in Africa and the Middle East as two separate settings, a view that unfortunately is still prevalent. Also, WWI studies have tended to examine the conflict within the geographical contours created by the area studies paradigm. Adopted in the 1950s, the area studies model has been under scrutiny since the mid-1990s.73 The artificial disjuncture between Sub-Saharan Africa, North Africa, and the Middle East reveals all its inadequacies when we deal with the Horn of Africa, an area strongly connected to the neighboring regions. Our choice to focus on a territory which stretches from Libya to Ethiopia and encompasses the Yemen and Middle East is an attempt to overcome this hiatus. Erasing the artificial lines that divide the Horn of Africa from the wider Red Sea region allows approaches that offer a greater understanding of the dynamics at work during WWI. Ours is only a partial attempt to address this methodological limit. But we are aware that Shar\u12bf Husayn\u2019s break with the Ottomans and the volatile situation in Yemen and along the Red Sea deserves more attention from scholars of African history