1,841 research outputs found
TARGET: A Digitizing And Trigger ASIC For The Cherenkov Telescope Array
The future ground-based gamma-ray observatory Cherenkov Telescope Array (CTA)
will feature multiple types of imaging atmospheric Cherenkov telescopes, each
with thousands of pixels. To be affordable, camera concepts for these
telescopes have to feature low cost per channel and at the same time meet the
requirements for CTA in order to achieve the desired scientific goals. We
present the concept of the TeV Array Readout Electronics with GSa/s sampling
and Event Trigger (TARGET) Application Specific Circuit (ASIC), envisaged to be
used in the cameras of various CTA telescopes, e.g. the Gamma-ray Cherenkov
Telescope (GCT), a proposed 2-Mirror Small-Sized Telescope, and the
Schwarzschild-Couder Telescope (SCT), a proposed Medium-Sized Telescope. In the
latest version of this readout concept the sampling and trigger parts are split
into dedicated ASICs, TARGET C and T5TEA, both providing 16 parallel input
channels. TARGET C features a tunable sampling rate (usually 1 GSa/s), a 16k
sample deep buffer for each channel and on-demand digitization and transmission
of waveforms with typical spans of ~100 ns. The trigger ASIC, T5TEA, provides 4
low voltage differential signal (LVDS) trigger outputs and can generate a
pedestal voltage independently for each channel. Trigger signals are generated
by T5TEA based on the analog sum of the input in four independent groups of
four adjacent channels and compared to a threshold set by the user. Thus, T5TEA
generates four LVDS trigger outputs, as well as 16 pedestal voltages fed to
TARGET C independently for each channel. We show preliminary results of the
characterization and testing of TARGET C and T5TEA.Comment: 6 pages, 8 figures, Proceedings of the 6th International Symposium on
High-Energy Gamma-Ray Astronomy (Gamma2016
Testing the neutrality of matter by acoustic means in a spherical resonator
New measurements to test the neutrality of matter by acoustic means are
reported. The apparatus is based on a spherical capacitor filled with gaseous
SF excited by an oscillating electric field. The apparatus has been
calibrated measuring the electric polarizability. Assuming charge conservation
in the decay of the neutron, the experiment gives a limit of
for the electron-proton charge
difference, the same limit holding for the charge of the neutron. Previous
measurements are critically reviewed and found incorrect: the present result is
the best limit obtained with this technique
Hyperfine Structure of Thallium Chloride
The radio‐frequency spectra of TlCl at very weak electric and magnetic fields have been measured with a molecular beam electric resonance spectrometer. From these spectra the hyperfine interaction constants for the four isotopic species of the molecule were calculated. The constants for 205Tl35Cl in the J = 2,υ = 0J=2,υ=0 state are: eqQ = − 15793.32(50)kHz,cCl = 1.38(10)kHz,cTl = 76.35(10)kHz,c3 = − 0.13(10)kHz,c4 = − 1.54(10)kHz.eqQ=−15793.32(50)kHz,cCl=1.38(10)kHz,cTl=76.35(10)kHz,c3=−0.13(10)kHz,c4=−1.54(10)kHz. A test was made for the polarization of the chlorine nucleus in the electric field of the molecule by comparing the ratio of the quadrupole interaction constants for 205Tl35Cl and 205Tl37Cl to the ratio of the quadrupole interaction constants for the free chlorine atoms. The agreement of the two ratios is within their uncertainties, thus providing no evidence for a polarization effect. In addition, the dependence of the spin–rotation and spin–spin interaction constants on isotope was found to show good agreement with theory.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69724/2/JCPSA6-50-5-2086-1.pd
Developing User‐Friendly Habitat Suitability Tools from Regional Stream Fish Survey Data
We developed user‐friendly fish habitat suitability tools (plots) for fishery managers in Michigan; these tools are based on driving habitat variables and fish population estimates for several hundred stream sites throughout the state. We generated contour plots to show patterns in fish biomass for over 60 common species (and for 120 species grouped at the family level) in relation to axes of catchment area and low‐flow yield (90% exceedance flow divided by catchment area) and also in relation to axes of mean and weekly range of July temperatures. The plots showed distinct patterns in fish habitat suitability at each level of biological organization studied and were useful for quantitatively comparing river sites. We demonstrate how these plots can be used to support stream management, and we provide examples pertaining to resource assessment, trout stocking, angling regulations, chemical reclamation of marginal trout streams, indicator species, instream flow protection, and habitat restoration. These straightforward and effective tools are electronically available so that managers can easily access and incorporate them into decision protocols and presentations.Received April 9, 2010; accepted November 8, 2010Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141005/1/nafm0041.pd
Minor Histocompatibility Antigen DBY Elicits a Coordinated B and T Cell Response after Allogeneic Stem Cell Transplantation
We examined the immune response to DBY, a model H-Y minor histocompatibility antigen (mHA) in a male patient with chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplant from a human histocompatibility leukocyte antigen (HLA)-identical female sibling. Patient peripheral blood mononuclear cells were screened for reactivity against a panel of 93 peptides representing the entire amino acid sequence of DBY. This epitope screen revealed a high frequency CD4(+) T cell response to a single DBY peptide that persisted from 8 to 21 mo after transplant. A CD4(+) T cell clone displaying the same reactivity was established from posttransplant patient cells and used to characterize the T cell epitope as a 19-mer peptide starting at position 30 in the DBY sequence and restricted by HLA-DRB1*1501. Remarkably, the corresponding X homologue peptide was also recognized by donor T cells. Moreover, the T cell clone responded equally to mature HLA-DRB1*1501 male and female dendritic cells, indicating that both DBY and DBX peptides were endogenously processed. After transplant, the patient also developed antibodies that were specific for recombinant DBY protein and did not react with DBX. This antibody response was mapped to two DBY peptides beginning at positions 118 and 536. Corresponding DBX peptides were not recognized. These studies provide the first demonstration of a coordinated B and T cell immune response to an H-Y antigen after allogeneic transplant. The specificity for recipient male cells was mediated by the B cell response and not by donor T cells. This dual DBX/DBY antigen is the first mHA to be identified in the context of chronic GVHD
Confinement effects on glass forming liquids probed by DMA
Many molecular glass forming liquids show a shift of the glass transition T-g
to lower temperatures when the liquid is confined into mesoporous host
matrices. Two contrary explanations for this effect are given in literature:
First, confinement induced acceleration of the dynamics of the molecules leads
to an effective downshift of T-g increasing with decreasing pore size. Second,
due to thermal mismatch between the liquid and the surrounding host matrix,
negative pressure develops inside the pores with decreasing temperature, which
also shifts T-g to lower temperatures. Here we present dynamic mechanical
analysis measurements of the glass forming liquid salol in Vycor and Gelsil
with pore sizes of d=2.6, 5.0 and 7.5 nm. The dynamic complex elastic
susceptibility data can be consistently described with the assumption of two
relaxation processes inside the pores: A surface induced slowed down relaxation
due to interaction with rough pore interfaces and a second relaxation within
the core of the pores. This core relaxation time is reduced with decreasing
pore size d, leading to a downshift of T-g proportional to 1/d in perfect
agreement with recent differential scanning calorimetry (DSC) measurements.
Thermal expansion measurements of empty and salol filled mesoporous samples
revealed that the contribution of negative pressure to the downshift of T-g is
small (<30%) and the main effect is due to the suppression of dynamically
correlated regions of size xi when the pore size xi approaches
Investigating organic aerosol loading in the remote marine environment
Aerosol loading in the marine environment is investigated using aerosol composition measurements from several research ship campaigns (ICEALOT, MAP, RHaMBLe, VOCALS and OOMPH), observations of total AOD column from satellite (MODIS) and ship-based instruments (Maritime Aerosol Network, MAN), and a global chemical transport model (GEOS-Chem). This work represents the most comprehensive evaluation of oceanic OM emission inventories to date, by employing aerosol composition measurements obtained from campaigns with wide spatial and temporal coverage. The model underestimates AOD over the remote ocean on average by 0.02 (21 %), compared to satellite observations, but provides an unbiased simulation of ground-based Maritime Aerosol Network (MAN) observations. Comparison with cruise data demonstrates that the GEOS-Chem simulation of marine sulfate, with the mean observed values ranging between 0.22 μg m−3 and 1.34 μg m−3, is generally unbiased, however surface organic matter (OM) concentrations, with the mean observed concentrations between 0.07 μg m−3 and 0.77 μg m−3, are underestimated by a factor of 2–5 for the standard model run. Addition of a sub-micron marine OM source of approximately 9 TgC yr−1 brings the model into agreement with the ship-based measurements, however this additional OM source does not explain the model underestimate of marine AOD. The model underestimate of marine AOD is therefore likely the result of a combination of satellite retrieval bias and a missing marine aerosol source (which exhibits a different spatial pattern than existing aerosol in the model)
The H1 Forward Proton Spectrometer at HERA
The forward proton spectrometer is part of the H1 detector at the HERA
collider. Protons with energies above 500 GeV and polar angles below 1 mrad can
be detected by this spectrometer. The main detector components are
scintillating fiber detectors read out by position-sensitive photo-multipliers.
These detectors are housed in so-called Roman Pots which allow them to be moved
close to the circulating proton beam. Four Roman Pot stations are located at
distances between 60 m and 90 m from the interaction point.Comment: 20 pages, 10 figures, submitted to Nucl.Instr.and Method
Modeling abundance using N-mixture models: the importance of considering ecological mechanisms
Predicting abundance across a species' distribution is useful for studies of ecology and biodiversity management. Modeling of survey data in relation to environmental variables can be a powerful method for extrapolating abundances across a species' distribution and, consequently, calculating total abundances and ultimately trends. Research in this area has demonstrated that models of abundance are often unstable and produce spurious estimates, and until recently our ability to remove detection error limited the development of accurate models. The N-mixture model accounts for detection and abundance simultaneously and has been a significant advance in abundance modeling. Case studies that have tested these new models have demonstrated success for some species, but doubt remains over the appropriateness of standard N-mixture models for many species. Here we develop the N-mixture model to accommodate zero-inflated data, a common occurrence in ecology, by employing zero-inflated count models. To our knowledge, this is the first application of this method to modeling count data. We use four variants of the N-mixture model (Poisson, zero-inflated Poisson, negative binomial, and zero-inflated negative binomial) to model abundance, occupancy (zero-inflated models only) and detection probability of six birds in South Australia. We assess models by their statistical fit and the ecological realism of the parameter estimates. Specifically, we assess the statistical fit with AIC and assess the ecological realism by comparing the parameter estimates with expected values derived from literature, ecological theory, and expert opinion. We demonstrate that, despite being frequently ranked the “best model” according to AIC, the negative binomial variants of the N-mixture often produce ecologically unrealistic parameter estimates. The zero-inflated Poisson variant is preferable to the negative binomial variants of the N-mixture, as it models an ecological mechanism rather than a statistical phenomenon and generates reasonable parameter estimates. Our results emphasize the need to include ecological reasoning when choosing appropriate models and highlight the dangers of modeling statistical properties of the data. We demonstrate that, to obtain ecologically realistic estimates of abundance, occupancy and detection probability, it is essential to understand the sources of variation in the data and then use this information to choose appropriate error distributions. Copyright ESA. All rights reserved
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