102 research outputs found

    PDMAC: A Priority-based Enhanced TDMA Protocol for Warning Message Dissemination in VANETs

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    Vehicular Ad hoc Networks (VANETs) are the key enabling technology for intelligent transportation systems. Carrier-Sense Multiple Access with Collision Avoidance (CSMA/CA) is the de facto media access standard for inter-vehicular communications, but its performance degrades in high-density networks. Time-Division Multiple Access (TDMA)-based protocols fill this gap to a certain extent, but encounter inefficient clock synchronization and lack of prioritized message delivery. To this end, we propose a Priority-based Direction-aware Media Access Control (PDMAC) as a novel protocol for intra-cluster and inter-cluster clock synchronization. Furthermore, PDMAC pioneers a three-tier priority assignment technique to enhance warning messages delivery by taking into account the direction component, message type, and severity level on each tier. Analytical and simulation results validate the improved performance of PDMAC in terms of clock synchronization, channel utilization, message loss rate, end-to-end delays and network throughput, as compared with eminent VANET MAC protocols

    A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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    AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

    Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring

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    Ex Situ Catalytic Pyrolysis of Invasive <i>Pennisetum purpureum</i> Grass with Activated Carbon for Upgrading Bio-Oil

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    Energy demands keep increasing in this modern world as the world population increases, which leads to a reduction in fossil fuels. To resolve these challenges, Pennisetum purpureum, an invasive grass in Brunei Darussalam, was examined as the feedstock for renewable energy through a catalytic pyrolysis process. The activated carbon was applied as the catalyst for a simple and economical solution. The catalytic pyrolysis was executed at 500 °C (the temperature for the highest biofuel yield) for both reactors to produce the highest amount of upgraded biofuels. The biochar produced from the non-catalytic and catalytic pyrolysis processes showed a consistent yield due to stable operating conditions, from which the activated carbon was generated and used as the catalyst in this work. A significant amount of improvement was found in the production of biofuels, especially bio-oil. It was found that for catalysts, the number of phenolic, alcohol, furans, and ketones was increased by reducing the amount of acidic, aldehyde, miscellaneous oxygenated, and nitrogenous composites in bio-oils. The highest amount of phenolic compounds was produced due to a number of functional groups (-C=O and -OH) in activated carbon. The regenerated activated carbons also showed promising outcomes as catalysts for upgrading the bio-oils. The overall performance of synthesized and regenerated activated carbon as a catalyst in catalytic pyrolysis was highly promising for improving the quality and stability of bio-oil
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