Skin involvement as the presenting sign of a male breast cancer

Male breast cancer is a rare disease with an unknown etiopathogenesis. We report a case of a 50-year-old man with a breast cancer revealed by skin involvement

On the use of ABACUS high resolution glider observations for the assessment of phytoplankton ocean biomass from CMEMS model products

Ocean biomass distribution has a growing importance in the world economy as a global strategic reserve, due to environmental and industrial applications and its variability related to climate change. Satellite imagery allows multi-resolution methodologies to obtain estimation, and hopefully classification, of biomass content over sea surface. This information is largely used in numerical simulations and nowadays represents an important contribute to future projections. Nevertheless, satellite, models and classical in situ monitoring resolution/accuracy sometimes cannot provide data at the finer spatial scales needed to describe the complex three-dimensional water column system. On the other hand, glider surveys allow scientists to collect observations of ocean phenomena at very high resolution along the water column, to assess numerical simulations reliability and, eventually, to assimilate these data into ocean models. In this study, we present a quantitative comparison between the glider observations collected in the Algerian Basin (Western Mediterranean Sea) during the ABACUS surveys from 2014 to 2018, and the daily outputs of two co-located CMEMS model products (i.e., GLB and IBI). The achieved results point out that model products are well correlated with glider potential temperature measurements but they still need improvements to provide a correct representation of the chlorophyll concentration variability in the study area. Generally, IBI daily simulations present higher linear correlation with concurrent glider in situ data than GLB ones. IBI products also reproduce better the pattern of the local maxima of chlorophyll concentration across the Algerian Basin. Nevertheless, they largely underestimate glider chlorophyll measurements and present significant differences that limit their capability to reproduce its upper ocean concentration that is needed for accomplishing advanced ecological studies.This work was realized in the framework of the PON R&I 2014–2020 “AIM – Attraction and International Mobility” at Università degli Studi di Napoli Parthenope. Glider missions were performed in the framework of the Algerian BAsin Circulation Unmanned Survey (ABACUS) observational projects. The ABACUS 1 missions (2014) were supported by the Joint European Research Infrastructure network for Coastal Observatories (JERICO) TransNational Access (TNA) third call (grant agreement no. 262584). The ABACUS 2 missions (2015) were realized through the SOCIB glider facility open access programme. The research leading to ABACUS 3 (2016) and ABACUS 4 (2017 and 2018) was supported by the European Union's H2020 Framework Programme (h2020-INFRAIA-2014–2015) (JERICOsingle bondNEXT grant agreement no. 654410).Peer reviewe

PAWS: A performance evaluation tool for parallel computing systems

A description is given of PAWS (parallel assessment window system), a set of tools that provides an interactive user-friendly environment for analysis of existing, prototype, and conceptual machine architectures running a common application. PAWS consists of an application tool, an architectural characterization tool, a performance assessment tool, and an interactive graphical display tool. The application characterization tool provides a facility for evaluating the level and degree of an application's parallelism. The architecture characterization tool allows users to create, store, and retrieve descriptions of machines in a database. This approach permits users to evaluate conceptual machines before building any hardware. The performance assessment tool generates profile plots through the interactive graphical display tool. It shows both the ideal parallelism inherent in the machine-independent dataflow graph and

Réflexion sur la stérilisation hospitalière des dispositifs médicaux (exemple de l'Assistance publique-hôpitaux de Marseille)

AIX-MARSEILLE2-BU Pharmacie (130552105) / SudocSudocFranceF

Skin involvement as the presenting sign of a male breast cancer

Male breast cancer is a rare disease with an unknown etiopathogenesis. We report a case of a 50-year-old man with a breast cancer revealed by skin involvement

Monte Carlo Poration Model of Cell Membranes for Application to Plasma Gene Transfection

International audienc

A surface acoustic wave sensor functionalized with a polypyrrole molecularly imprinted polymer for selective dopamine detection

International audienc

Integrated architectural application characterization tools for comparative assessment of parallel systems

PAWS (Parallel Assessment Window System) is an experimental research tool currently operational at Syracuse University that provides a single unified environment for performing application specific analysis for existing, prototype, and conceptual machine architectures. The flexibility of the system allows comparisons among vastly different machine architectures running a common application. PAWS consists of four tools; an application characterization tool, an architecture characterization tool, an interactive graphic display tool (IGDT), and a performance assessment tool (PAT). Using the application characterization tool, Ada programs are transformed into machine independent data flow graphs and displayed showing the parallelism contained in the application to the user. These graphs are partitioned onto a target machine, based on that machine's attributes, which are created and stored using the architectural

Morocco’s First Biobank: Establishment, Ethical Issues, Biomedical Research Opportunities, and Challenges

Background. Biobanks are highly organized infrastructures that allow the storage of human biological specimens associated with donors’ personal and clinical data. These infrastructures play a key role in the development of translational medical research. In this context, we launched, in November 2015, the first biobank in Morocco (BRO Biobank) in order to promote biomedical research and provide opportunities to include Moroccan and North African ethnic groups in international biomedical studies. Here, we present the setup and the sample characteristics of BRO Biobank. Methods. Patients were recruited at several departments of two major health-care centers in the city of Oujda. Healthy donors were enrolled during blood donation campaigns all over Eastern Morocco. From each participant, personal, clinical, and biomedical data were collected, and several biospecimens were stored. Standard operating procedures have been established in accordance with international guidelines on human biobanks. Results. Between November 2015 and July 2020, 2446 participants were recruited into the BRO Biobank, of whom 2013 were healthy donors, and 433 were patients. For healthy donors, the median age was 35 years with a range between 18 and 65 years and the consanguinity rate was 28.96%. For patients, the median age was 11 years with a range between 1 day and 83 years. Among these patients, 55% had rare diseases (hemoglobinopathies, intellectual disabilities, disorders of sex differentiation, myopathies, etc.), 13% had lung cancer, 4% suffered from hematological neoplasms, 3% were from the kidney transplantation project, and 25% had unknown diagnoses. The BRO Biobank has collected 5092 biospecimens, including blood, white blood cells, plasma, serum, urine, frozen tissue, FFPE tissue, and nucleic acids. A sample quality control has been implemented and suggested that samples of the BRO Biobank are of high quality and therefore suitable for high-throughput nucleic acid analysis. Conclusions. The BRO Biobank is the largest sample collection in Morocco, and it is ready to provide samples to national and international research projects. Therefore, the BRO Biobank is a valuable resource for advancing translational medical research