First data from DM-Ice17

We report the first analysis of background data from DM-Ice17, a direct-detection dark matter experiment consisting of 17 kg of NaI(Tl) target material. It was codeployed with IceCube 2457 m deep in the South Pole glacial ice in December 2010 and is the first such detector operating in the Southern Hemisphere. The background rate in the 6.5–8.0 keVee region is measured to be 7.9 � 0.4 counts=day=keV=kg. This is consistent with the expected background from the detector assemblies with negligible contributions from the surrounding ice. The successful deployment and operation of DM-Ice17 establishes the South Pole ice as a viable location for future underground, low-background experiments in the Southern Hemisphere. The detector assembly and deployment are described here, as well as the analysis of the DM-Ice17 backgrounds based on data from the first two years of operation after commissioning, July 2011–June 2013

Measurement of muon annual modulation and muon-induced phosphorescence in NaI(TI) crystals with DM-Ice17

We report the measurement of muons and muon-induced phosphorescence in DM-Ice17, a NaI(Tl) direct detection dark matter experiment at the South Pole. Muon interactions in the crystal are identified by their observed pulse shape and large energy depositions. The measured muon rate in DM-Ice17 is 2.93±0.04  μ/crystal/day with a modulation amplitude of 12.3±1.7%, consistent with expectation. Following muon interactions, we observe long-lived phosphorescence in the NaI(Tl) crystals with a decay time of 5.5±0.5  s. The prompt energy deposited by a muon is correlated to the amount of delayed phosphorescence, the brightest of which consist of tens of millions of photons. These photons are distributed over tens of seconds with a rate and arrival timing that do not mimic a scintillation signal above 2  keVee. While the properties of phosphorescence vary among individual crystals, the annually modulating signal observed by DAMA cannot be accounted for by phosphorescence with the characteristics observed in DM-Ice17

First search for a dark matter annual modulation signal with NaI(Tl) in the Southern Hemisphere by DM-Ice17

We present the first search for a dark matter annual modulation signal in the Southern Hemisphere conducted with NaI(Tl) detectors, performed by the DM-Ice17 experiment. Nuclear recoils from dark matter interactions are expected to yield an annually modulated signal independent of location within the Earth’s hemispheres. DM-Ice17, the first step in the DM-Ice experimental program, consists of 17 kg of NaI(Tl) located at the South Pole under 2200 m.w.e. overburden of Antarctic glacial ice. Taken over 3.6 years for a total exposure of 60.8 kg yr, DM-Ice17 data are consistent with no modulation in the energy range of 4–20 keV, providing the strongest limits on weakly interacting massive particle dark matter from a direct detection experiment located in the Southern Hemisphere. The successful deployment and stable long-term operation of DM-Ice17 establishes the South Pole ice as a viable location for future dark matter searches and in particular for a high-sensitivity NaI(Tl) dark matter experiment to directly test the DAMA/LIBRA claim of the observation of dark matter

Muon detector for the COSINE-100 experiment

The COSINE-100 dark matter search experiment has started taking physics data with the goal of performing an independent measurement of the annual modulation signal observed by DAMA/LIBRA. A muon detector was constructed by using plastic scintillator panels in the outermost layer of the shield surrounding the COSINE-100 detector. It detects cosmic ray muons in order to understand the impact of the muon annual modulation on dark matter analysis. Assembly and initial performance tests of each module have been performed at a ground laboratory. The installation of the detector in the Yangyang Underground Laboratory (Y2L) was completed in the summer of 2016. Using three months of data, the muon underground flux was measured to be 328 ± 1(stat.)± 10(syst.) muons/m2/day. In this report, the assembly of the muon detector and the results from the analysis are presented

Presynaptic External Calcium Signaling Involves the Calcium-Sensing Receptor in Neocortical Nerve Terminals

Nerve terminal invasion by an axonal spike activates voltage-gated channels, triggering calcium entry, vesicle fusion, and release of neurotransmitter. Ion channels activated at the terminal shape the presynaptic spike and so regulate the magnitude and duration of calcium entry. Consequently characterization of the functional properties of ion channels at nerve terminals is crucial to understand the regulation of transmitter release. Direct recordings from small neocortical nerve terminals have revealed that external [Ca(2+)] ([Ca(2+)](o)) indirectly regulates a non-selective cation channel (NSCC) in neocortical nerve terminals via an unknown [Ca(2+)](o) sensor. Here, we identify the first component in a presynaptic calcium signaling pathway.By combining genetic and pharmacological approaches with direct patch-clamp recordings from small acutely isolated neocortical nerve terminals we identify the extracellular calcium sensor. Our results show that the calcium-sensing receptor (CaSR), a previously identified G-protein coupled receptor that is the mainstay in serum calcium homeostasis, is the extracellular calcium sensor in these acutely dissociated nerve terminals. The NSCC currents from reduced function mutant CaSR mice were less sensitive to changes in [Ca(2+)](o) than wild-type. Calindol, an allosteric CaSR agonist, reduced NSCC currents in direct terminal recordings in a dose-dependent and reversible manner. In contrast, glutamate and GABA did not affect the NSCC currents.Our experiments identify CaSR as the first component in the [Ca(2+)](o) sensor-NSCC signaling pathway in neocortical terminals. Decreases in [Ca(2+)](o) will depress synaptic transmission because of the exquisite sensitivity of transmitter release to [Ca(2+)](o) following its entry via voltage-activated Ca(2+) channels. CaSR may detects such falls in [Ca(2+)](o) and increase action potential duration by increasing NSCC activity, thereby attenuating the impact of decreases in [Ca(2+)](o) on release probability. CaSR is positioned to detect the dynamic changes of [Ca(2+)](o) and provide presynaptic feedback that will alter brain excitability

Initial performance of the COSINE-100 experiment

COSINE is a dark matter search experiment based on an array of low background NaI(Tl) crystals located at the Yangyang underground laboratory. The assembly of COSINE-100 was completed in the summer of 2016 and the detector is currently collecting physics quality data aimed at reproducing the DAMA/LIBRA experiment that reported an annual modulation signal. Stable operation has been achieved and will continue for at least 2 years. Here, we describe the design of COSINE-100, including the shielding arrangement, the configuration of the NaI(Tl) crystal detection elements, the veto systems, and the associated operational systems, and we show the current performance of the experiment