Comparison of two methods of noise power spectrum determinations of medical radiography systems

Noise in medical images is recognized as an important factor that determines the image quality. Image noise is characterized by noise power spectrum (NPS). We compared two methods of NPS determination namely the methods of Wagner and Dobbins on Lanex Regular TMG screen-film system and Hologic Lorad Selenia full field digital mammography system, with the aim of choosing the better method to use. The methods differ in terms of various parametric choices and algorithm implementations. These parameters include the low pass filtering, low frequency filtering, windowing, smoothing, aperture correction, overlapping of region of interest (ROI), length of fast Fourier transform, ROI size, method of ROI normalization, and slice selection of the NPS. Overall, the two methods agreed to the practical value of noise power spectrum between 10 -3-10-6mm2 over spatial frequency range 0-10mm-1

Design of a 2.4 GHz High-Performance Up-Conversion Mixer with Current Mirror Topology

In this paper, a low voltage low power up-conversion mixer, designed in a Chartered 0.18 μm RFCMOS technology, is proposed to realize the transmitter front-end in the frequency band of 2.4 GHz. The up-conversion mixer uses the current mirror topology and current-bleeding technique in both the driver and switching stages with a simple degeneration resistor. The proposed mixer converts an input of 100 MHz intermediate frequency (IF) signal to an output of 2.4 GHz radio frequency (RF) signal, with a local oscillator (LO) power of 2 dBm at 2.3 GHz. A comparison with conventional CMOS up-conversion mixer shows that this mixer has advantages of low voltage, low power consumption and high-performance. The post-layout simulation results demonstrate that at 2.4 GHz, the circuit has a conversion gain of 7.1 dB, an input-referred third-order intercept point (IIP3) of 7.3 dBm and a noise figure of 11.9 dB, while drawing only 3.8 mA for the mixer core under a supply voltage of 1.2 V. The chip area including testing pads is only 0.62×0.65 mm2

Model B4 : multi-decade creep and shrinkage prediction of traditional and modern concretes

To improve the sustainability of concrete infrastructure, engineers face the challenge of incorporating new concrete materials while pushing the expected design life beyond 100 years. The time-dependent creep and shrinkage response of concrete governs the serviceability and durability in this multi-decade time frame. It has been shown that current prediction equations for creep and shrinkage underestimate material deformations observed in structures outside of a laboratory environment. A new prediction model for creep and shrinkage is presented that can overcome some of the shortcomings of the current equations. The model represents an extension and systematic recalibration of model B3, a 1995 RILEM Recommendation, which derives its functional form from the phenomena of diffusion, chemical hydration, moisture sorption, and the evolution of micro-stresses in the cement structure. The model is calibrated through a joint optimization of a new enlarged laboratory test database and a new database of bridge deflection records to overcome the bias towards short-term behavior. A framework for considering effects of aggregates, admixtures, additives, and higher temperatures is also incorporated

Structure of the Ds0(2317)D_{s0}(2317) and the strong coupling constant gDs0DKg_{D_{s0} D K} with the light-cone QCD sum rules

In this article, we take the point of view that the charmed scalar meson $D_{s0}(2317)$ is the conventional $c\bar{s}$ meson and calculate the strong coupling constant $g_{D_{s0} D K}$ within the framework of the light-cone QCD sum rules approach. The numerical values for the large scalar-$DK$ coupling constant $g_{D_{s0} D K}$ support the hadronic dressing mechanism. Just like the scalar mesons $f_0(980)$ and $a_0(980)$, the $D_{s0}(2317)$ may have small scalar $c\bar{s}$ kernel of the typical $c\bar{s}$ meson size. The strong coupling to the hadronic channels (or the virtual mesons loops) may result in smaller mass than the conventional scalar $c\bar{s}$ meson in the constituent quark models, and enrich the pure $c\bar{s}$ state with other components. The $D_{s0}(2317)$ may spend part (or most part) of its lifetime as virtual $D K$ state.Comment: 17 pages, 7 figure, revised version, add detailed error analysi

Long-term, low-dose lead exposure alters the gonadotropin-releasing hormone system in the male rat.

Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes were attenuated with increased concentration of exposure. The current study evaluated whether exposure to low levels of lead acetate over longer periods of time would produce a similar pattern of adaptation to toxicity at the molecular and biologic levels. Adult 100-day-old Sprague-Dawley male rats were dosed with 0, 0.025, 0.05, 0.1, and 0.3% lead acetate in water. Animals were killed after 1, 4, 8, and 16 weeks of treatment. Luteinzing hormone (LH) and GnRH levels were measured in serum, and lead levels were quantified in whole blood. Hypothalamic GnRH mRNA levels were also quantified. We found no significant differences in serum LH and GnRH among the groups of animals treated within each time period. A significant dose-related increase of GnRH mRNA concentrations with lead dosing occurred in animals treated for 1 week. Animals treated for more than 1 week also exhibited a significant increase in GnRH mRNA, but with an attenuation of the increase at the higher concentrations of lead with increased duration of exposure. We conclude that the signals within and between the hypothalamus and pituitary gland appear to be disrupted by long-term, low-dose lead exposure