1,846 research outputs found
Possible interpretation of the (10610) and (10650) in a chiral quark model
Motivated by the two charged bottomonium-like resonances (10610) and
(10650) newly observed by the Belle collaboration, the possible molecular
states composed of a pair of heavy mesons, , etc (in S-wave), are investigated in the framework of chiral quark
models by the Gaussian expansion method. The bound states and
with quantum numbers , which are good
candidates for the and respectively, are obtained.
Other three bound states with ,
with are predicted. These
states may be observed in open-bottom or hidden-bottom decay channel of highly
excited . When extending directly the quark model to the hidden color
channel of the multi-quark system, more deeply bound states are found. Future
experimental search of those states will cast doubt on the validity of applying
the chiral constituent quark model to the hidden color channel directly.Comment: 13 pages, 1 figure, title and some arguments in the abstract and
section 5 are revised, results unchange
c-Jun NH2-terminal kinase-dependent upregulation of DR5 mediates cooperative induction of apoptosis by perifosine and TRAIL
<p>Abstract</p> <p>Background</p> <p>Perifosine, an alkylphospholipid tested in phase II clinical trials, modulates the extrinsic apoptotic pathway and cooperates with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to augment apoptosis. The current study focuses on revealing the mechanisms by which perifosine enhances TRAIL-induced apoptosis.</p> <p>Results</p> <p>The combination of perifosine and TRAIL was more active than each single agent alone in inducing apoptosis of head and neck squamous cell carcinoma cells and inhibiting the growth of xenografts. Interestingly, perifosine primarily increased cell surface levels of DR5 although it elevated the expression of both DR4 and DR5. Blockade of DR5, but not DR4 upregulation, via small interfering RNA (siRNA) inhibited perifosine/TRAIL-induced apoptosis. Perifosine increased phosphorylated c-Jun NH<sub>2</sub>-terminal kinase (JNK) and c-Jun levels, which were paralleled with DR4 and DR5 induction. However, only DR5 upregulaiton induced by perifosine could be abrogated by both the JNK inhibitor SP600125 and JNK siRNA. The antioxidants, N-acetylcysteine and glutathione, but not vitamin C or tiron, inhibited perifosine-induced elevation of p-c-Jun, DR4 and DR5. Moreover, no increased production of reactive oxygen species was detected in perifosine-treated cells although reduced levels of intracellular GSH were measured.</p> <p>Conclusions</p> <p>DR5 induction plays a critical role in mediating perifosine/TRAIL-induced apoptosis. Perifosine induces DR5 expression through a JNK-dependent mechanism independent of reactive oxygen species.</p
Conductance of a Quantum Point Contact in the presence of a Scanning Probe Microscope Tip
Using the recursive Green's function technique, we study the coherent
electron conductance of a quantum point contact in the presence of a scanning
probe microscope tip. Images of the coherent fringe inside a quantum point
contact for different widths are obtained. It is found that the conductance of
a specific channel is reduced while other channels are not affected as long as
the tip is located at the positions correspending to that channel. Moreover,
the coherent fringe is smoothed out by increasing the temperature or the
voltage across the device. Our results are consistent with the experiments
reported by Topinka et al.[Science 289, 2323 (2000)].Comment: 5 page
Fast synthesis of platinum nanopetals and nanospheres for highly-sensitive non-enzymatic detection of glucose and selective sensing of ions
Novel methods to obtain Pt nanostructured electrodes have raised particular interest due to their high performance in electrochemistry. Several nanostructuration methods proposed in the literature use costly and bulky equipment or are time-consuming due to the numerous steps they involve. Here, Pt nanostructures were produced for the first time by one-step template-free electrodeposition on Pt bare electrodes. The change in size and shape of the nanostructures is proven to be dependent on the deposition parameters and on the ratio between sulphuric acid and chloride-complexes (i.e., hexachloroplatinate or tetrachloroplatinate). To further improve the electrochemical properties of electrodes, depositions of Pt nanostructures on previously synthesised Pt nanostructures are also performed. The electroactive surface areas exhibit a two order of magnitude improvement when Pt nanostructures with the smallest size are used. All the biosensors based on Pt nanostructures and immobilised glucose oxidase display higher sensitivity as compared to bare Pt electrodes. Pt nanostructures retained an excellent electrocatalytic activity towards the direct oxidation of glucose. Finally, the nanodeposits were proven to be an excellent solid contact for ion measurements, significantly improving the time-stability of the potential. The use of these new nanostructured coatings in electrochemical sensors opens new perspectives for multipanel monitoring of human metabolism
Measurement of proton electromagnetic form factors in in the energy region 2.00-3.08 GeV
The process of is studied at 22 center-of-mass
energy points () from 2.00 to 3.08 GeV, exploiting 688.5~pb of
data collected with the BESIII detector operating at the BEPCII collider. The
Born cross section~() of is
measured with the energy-scan technique and it is found to be consistent with
previously published data, but with much improved accuracy. In addition, the
electromagnetic form-factor ratio () and the value of the
effective (), electric () and magnetic () form
factors are measured by studying the helicity angle of the proton at 16
center-of-mass energy points. and are determined with
high accuracy, providing uncertainties comparable to data in the space-like
region, and is measured for the first time. We reach unprecedented
accuracy, and precision results in the time-like region provide information to
improve our understanding of the proton inner structure and to test theoretical
models which depend on non-perturbative Quantum Chromodynamics
Observation of in
Using a sample of events recorded with
the BESIII detector at the symmetric electron positron collider BEPCII, we
report the observation of the decay of the charmonium state
into a pair of mesons in the process
. The branching fraction is measured for the first
time to be , where the first uncertainty is
statistical, the second systematic and the third is from the uncertainty of
. The mass and width of the are
determined as MeV/ and
MeV.Comment: 13 pages, 6 figure
Observation of and confirmation of its large branching fraction
The baryonic decay is observed, and the
corresponding branching fraction is measured to be
, where the first uncertainty is statistical
and second systematic. The data sample used in this analysis was collected with
the BESIII detector operating at the BEPCII double-ring collider with
a center-of-mass energy of 4.178~GeV and an integrated luminosity of
3.19~fb. The result confirms the previous measurement by the CLEO
Collaboration and is of greatly improved precision, which may deepen our
understanding of the dynamical enhancement of the W-annihilation topology in
the charmed meson decays
Observation and study of the decay
We report the observation and study of the decay
using events
collected with the BESIII detector. Its branching fraction, including all
possible intermediate states, is measured to be
. We also report evidence for a structure,
denoted as , in the mass spectrum in the GeV/
region. Using two decay modes of the meson ( and
), a simultaneous fit to the mass spectra is
performed. Assuming the quantum numbers of the to be , its
significance is found to be 4.4, with a mass and width of MeV/ and MeV, respectively, and a
product branching fraction
. Alternatively, assuming , the
significance is 3.8, with a mass and width of MeV/ and MeV, respectively, and a product
branching fraction
. The angular distribution of
is studied and the two assumptions of the
cannot be clearly distinguished due to the limited statistics. In all
measurements the first uncertainties are statistical and the second systematic.Comment: 10 pages, 6 figures and 4 table
Improved measurement of the absolute branching fraction of
By analyzing 2.93 fb of data collected at GeV with the
BESIII detector, we measure the absolute branching fraction , which is consistent with previous measurements within
uncertainties but with significantly improved precision. Combining the Particle
Data Group values of , , and the lifetimes of the and
mesons with the value of measured in this work, we determine the following ratios of
partial widths: and .Comment: 9 pages; 8 figure
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