Experimental Evidence of Boundary Induced Coupling Currents in LHC Prototypes

The field quality of 10 m long LHC dipole models has been measured with short rotating coils to explore its dependence on time and position. Multipoles exhibit a longitudinal periodic variation, with period equal to the twist pitch length. This periodicity is shown here to have at least two components with very different time constants. The amplitude of the component with the shorter time constant, in the range of 100 to 300 s, depends on position and time. Larger amplitudes are measured at early times after a ramp and close to regions with incomplete cable transposition with respect to the non-uniform external field change. As the multipoles periodicity is due to current imbalance in the cables, we attribute the short time scale variations to the presence of space and time decaying boundary induced coupling currents (BICC's) in the cable. An estimate of their value is give

Analyticity and the NcN_c counting rule of SS matrix poles

By studying $\pi\pi$ scattering amplitudes in the large $N_c$ limit, we clarify the $N_c$ dependence of the $S$ matrix pole position. It is demonstrated that analyticity and the $N_c$ counting rule exclude the existence of $S$ matrix poles with ${\cal M}, \Gamma\sim O(1)$. Especially the properties of $\sigma$ and $f_0(980)$ with respect to the $1/N_c$ expansion are discussed. We point out that in general tetra-quark resonances do not exist.Comment: This paper replaces hep-ph/0412175. The latter is withdraw

Magnetic Field Quality of Short Superconducting Dipole Model Magnets for LHC

A series of 1-m long, 56 mm aperture dipole models has been built and tested at CERN within the scope of the R&D program for LHC. Here we report a summary of results of warm and cold steady state field measurements in these models, concentrating on the contribution of the coil geometry. The first allowed harmonics are clearly correlated to the coil azimuthal size, and the slope of the correlation can be predicted accurately

A user-friendly wearable single-channel EOG-based human-computer interface for cursor control

This paper presents a novel wearable single-channel electrooculography (EOG) based human-computer interface (HCI) with a simple system design and robust performance. In the proposed system, EOG signals for control are generated from double eye blinks, collected by a commercial wearable device (the NeuroSky MindWave headset), and then converted into a sequence of commands that can control cursor navigations and actions. The EOG-based cursor control system was tested on 8 subjects in indoor or outdoor environment, and the average accuracy is 84.42% for indoor uses and 71.50% for outdoor uses. Compared with other existing EOG-based HCI systems, this system is highly user-friendly and does not require any training. Therefore, this system has the potential to provide an easy-to-use and cheap assistive technique for locked-in patients who have lost their main body muscular abilities but with proper eye-condition. © 2015 IEEE.published_or_final_versio

Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma.

The clinical deployment of immune checkpoint inhibitors (ICIs) has created a tandem drive for the identification of biomarkers linked to benefit. Comprehensive genomic profiling was performed to evaluate the frequency of genomic biomarkers of ICI response in 755 patients with advanced hepatocellular carcinoma (HCC). Median age was 62 years' old, 73% were male, 46% had extrahepatic disease, 107 had documented hepatitis C, 96 had hepatitis B and 4 patients were coinfected. Median tumor mutation burden (TMB) was 4 mutations/Mb and only 6 tumors (0.8%) were TMB-high. Out of 542 cases assessed for microsatellite instability (MSI), one (0.2%) was MSI-high and TMB-high. Twenty-seven (4%) patients had POLE/D alterations. One patient had a pathogenic POLE R762W mutation but TMB was 4 mutations/Mb. Forty percent had DNA damage response gene alterations. In a small case series (N=17) exploring the relationship between biomarkers and ICI response, one patient (TMB 15 mutations/Mb, MSI-low) had a sustained complete response to nivolumab lasting > 2 years. Otherwise there were no significant genomic or TMB differences between responders, progressors, and those with stable disease. Overall, markers of genomic instability were infrequent in this cohort. Larger clinically annotated datasets are needed to explore genomic and non-genomic determinants of ICI response in HCC

Field Quality of the Short Superconducting Dipole Models for the LHC

A full characterization of the magnetic field in warm and cold conditions was performed as a part of the standard test on the LHC 1-m long superconducting dipole models. Furthermore, dedicated measurement campaigns addressed the effect of current cycles and quenches on field quality. Powering and quenches were found to generate characteristic instabilities in the geometric harmonics. Detailed results are presented on this phenomenon, as well as correlations between warm and cold measurements and field reconstructions

Curb-intersection feature based Monte Carlo Localization on urban roads

One of the most prominent features on an urban road is the curb, which defines the boundary of a road surface. An intersection is a junction of two or more roads, appearing where no curb exists. The combination of curb and intersection features and their idiosyncrasies carry significant information about the urban road network that can be exploited to improve a vehicle's localization. This paper introduces a Monte Carlo Localization (MCL) method using the curb-intersection features on urban roads. We propose a novel idea of “Virtual LIDAR” to get the measurement models for these features. Under the MCL framework, above road observation is fused with odometry information, which is able to yield precise localization. We implement the system using a single tilted 2D LIDAR on our autonomous test bed and show robust performance in the presence of occlusion from other vehicles and pedestrians

Coil Size and Geometric Field Quality in Short Model Dipoles for LHC

We have measured the magnetic field at room temperature and at 1.8 K on more than twenty, 1-m long, single aperture LHC superconducting dipole models. The magnets feature either a 5-block coil geometry or the baseline 6-block geometry foreseen for the LHC. Comparison of warm and cold measurements show that the coil geometry is essentially unchanged during cooldown. We have therefore used mechanical measurements taken on the coil and collars during assembly to estimate the azimuthal coil length. Based on these measurements we show here that the sensitivity of allowed harmonics on coil size is in good agreement with the prediction obtained from the numerical model used for designing the LHC magnets

Identification of material properties of orthotropic composite plate using hybrid non-destructive evaluation approach

Identification of material properties is one of the key issues in composite materials research. The mechanical properties of composite materials depend on diverse factors such as configuration of the laminates, constituent materials used and production method adopted. Conventional testing approach tends to be time-consuming, expensive and destructive. As an alternative, a rapid, inexpensive, hybrid and non-destructive evaluation approach which utilises experimental modal analysis and finite element analysis is proposed. Experimental modal data which consist of natural frequencies and mode shapes of an orthotropic composite plate are utilised for correlation purpose with its finite element model. This finite element model of the composite plate is continuously updated and achieves less than 5% in difference of natural frequencies and over 70% in modal assurance criterion. Material properties such as Young's moduli, inplane shear modulus and Poisson ratio of the composite plate are then successfully determined using the well-correlated FE model