Soil suitability evaluation for rain-fed maize production at Gabari District Zaria Kaduna State, Nigeria

The need to generate adequate information for optimal and sustainable exploitation of the soils of Gabari District Zaria is imperative. The FAO land suitability evaluation was used to evaluate the soils for rain-fed maize cultivation. The total land area surveyed was 70 ha. Three soil units was mapped and designated as GBI 12.3 ha, GBII 38.8 ha and GBIII 18.9 ha. Generally, the surface texture was loam. The soil reactions were slightly acidic to neutral, organic carbon, available phosphorus and total nitrogen was rated low. The CEC (NH4OAc) were medium to high and Base saturation was rated medium while EC and ESP were low. Generally, there were no significant differences in the physical and chemical properties within the three mapping units. Soil mapping units GBI and GBIII were marginally suitable (S3) while GBII was currently not suitable (N1) for maize production due to limitation imposed by soil chemical properties and slope. With proper soil fertility management, the potentials of these soils can be increased to moderately suitable (S2) for rain-fed maize and other arable crops if recommended fertilization and uses of organic manure to improve the soils physical and chemical constraints as well as construction of contour ploughing in unit GBII to reduce the rate of erosion.Keywords: Soil, Suitability Evaluation, Agricultural potential, Gabari Distric

Penyuluhan E-Commerce untuk Mendorong Ekonomi Digital Dalam Rangka Pengabdian Kepada Masyarakat pada Pemuda Tridharma Indonesia Cabang Wihara Dharma Pala

Perkembangan  teknologi  informasi  di  era  revolusi  4.0  memberikan  dampak  yang signifikan terhadap perekonomian Indonesia. Platform digital dalam mendukung kegiatan perekonomian dan pemenuhan kebutuhan masyarakat bertumbuh dengan cepat dengan dukungan internet. dengan diterapkannya teknologi baru akan berdampak pada produkvitas dan menurunkan biaya produksi yang akan meningkatkan daya beli sehingga akan tercipta lapangan kerja baru. Metode kegiatan Pengabdian Kepada Masyarakat ini dilakukan melalui 4 tahapan (metode) yaitu metode sosialisasi, metode demonstrasi, metode praktek/latihan, evaluasi kegiatan. Pelaksanaan PkM ini melibatkan mitra kerjasama, yaitu Wihara Dharma Pala yang beralamat di Jl. Ir. Soekarno Kp, Jl. Raya Rawa Kompeni No.66, RT.003/RW.008, Benda, Kec. Benda, Kota Tangerang, Banten 15125. Tim pelaksana kegiatan Pengabdian kepada Masyarakat (PkM) terdiri dari 4 orang dosen & 1 orang mahasiswa. Tim dosen pelaksana Pkm terdiri atas dosen-dosen yang memiliki keterampilan & kemampuan dibidang teknologi informasi yang sesuai dengan tema PkM yang dilaksanakan serta memiliki kualifikasi akademik. Dari hasil hasil evaluasi yang dilakukan oleh Tim Pelaksana, dapat disimpulkan hal bahwa mayoritas peserta yang mengikuti kegiatan ini, sudah mengetahui tentang E-Commerce dan peserta masih kurang pengalaman dalam menggunakan layanan E-commerce seperti Market Place

Optimasi Penyediaan Internet Murah Dengan Kecepatan Yang Baik Guna Media Pembelajaran Jarak Jauh

Kesadaran pendidikan secara umum, kemampuan panduan teknologi dan kemampuan pembelajaran online masih rendah, sehingga menyulitkan orang tua dan siswa (terutama siswa sekolah dasar) guna menggunakan fasilitas teknologi dan memperoleh informasi dari pembelajaran. Berdasarkan paparan di atas, berikut beberapa permasalahan yang dapat diidentifikasi: 1) Tidak semua warga di lingkungan RT 06 RW 07 Griya Sangiang Mas memiliki fasilitas Internet yang cepat dan murah. Sebagai warga dan pendidik, kami berinisiatif menyediakan fasilitas internet murah dan cepat kemudian memberikan pelatihan. Secara umum kegiatan ini telah berlangsung selama 1 tahun, dan terdapat pengguna aktif pembelajaran sebanyak 15 siswa SD dan SMP setiap harinya. Secara umum bagi warga Perumahan Griya Sangiang Mas, Internet di RT ini bisa menjadi alternatif internet yang mura

Pelatihan Desain Poster dengan Canva

Perkembangan teknologi informasi dan komunikasi telah berkembang sangat pesat dan hampir telah mempengaruhi semua aspek kehidupan manusia. Dalam era teknologi informasi ini ditandai dengan kecepatan dan kemudahan untuk mendapatkan informasi yang dibutuhkan. Media grafis atau yang sering disebut sebagai media visual, merupakan salah media yang sudah banyak penggunaannya, salah satunya adalah poster. Dengan media visual berupa poster dapat dimanfaatkan untuk menyampaikan informasi lebih menarik dalam bentuk yang efektif dan efisien. Tujuan   dalam   pelatihan   ini   untuk   meningkatkan kreativitas terutama dalam membuat poster untuk menyampaikan informasi, adapun aplikasi yang digunakan adalah Canva. Pelatihan ini dilaksanakan selama satu hari, dengan melibatkan anggota Magabudhi. Pelaksanaan pelatihan dilakukan oleh dosen-dosen Fakultas Sains & Teknologi Universitas Buddhi Dharma. Setelah kegiatan pelatihan selesai, diharapkan para peserta sudah dapat membuat sebuah karya poster yang menarik untuk menyampaikan informasi dan memanfaatkan aplikasi canva untuk kebutuhan lainnya

Cellular responses to modified Plasmodium falciparum MSP119 antigens in individuals previously exposed to natural malaria infection

<p>Abstract</p> <p>Background</p> <p>MSP1 processing-inhibitory antibodies bind to epitopes on the 19 kDa C-terminal region of the <it>Plasmodium falciparum </it>merozoite surface protein 1 (MSP1₁₉), inhibiting erythrocyte invasion. Blocking antibodies also bind to this antigen but prevent inhibitory antibodies binding, allowing invasion to proceed. Recombinant MSP1₁₉had been modified previously to allow inhibitory but not blocking antibodies to continue to bind. Immunization with these modified proteins, therefore, has the potential to induce more effective protective antibodies. However, it was unclear whether the modification of MSP1₁₉would affect critical T-cell responses to epitopes in this antigen.</p> <p>Methods</p> <p>The cellular responses to wild-type MSP1₁₉and a panel of modified MSP1₁₉antigens were measured using an <it>in-vitro </it>assay for two groups of individuals: the first were malaria-naïve and the second had been naturally exposed to <it>Plasmodium falciparum </it>infection. The cellular responses to the modified proteins were examined using cells from malaria-exposed infants and adults.</p> <p>Results</p> <p>Interestingly, stimulation indices (SI) for responses induced by some of the modified proteins were at least two-fold higher than those elicited by the wild-type MSP1₁₉. A protein with four amino acid substitutions (Glu27→Tyr, Leu31→Arg, Tyr34→Ser and Glu43→Leu) had the highest stimulation index (SI up to 360) and induced large responses in 64% of the samples that had significant cellular responses to the modified proteins.</p> <p>Conclusion</p> <p>This study suggests that specific MSP1₁₉variants that have been engineered to improve their antigenicity for inhibitory antibodies, retain T-cell epitopes and the ability to induce cellular responses. These proteins are candidates for the development of MSP1-based malaria vaccines.</p

Epidemiology of neurodegenerative diseases in sub-Saharan Africa: a systematic review

BACKGROUND:Sub-Saharan African (SSA) countries are experiencing rapid transitions with increased life expectancy. As a result the burden of age-related conditions such as neurodegenerative diseases might be increasing. We conducted a systematic review of published studies on common neurodegenerative diseases, and HIV-related neurocognitive impairment in SSA, in order to identify research gaps and inform prevention and control solutions. METHODS: We searched MEDLINE via PubMed, 'Banque de Donnees de Sante Publique' and the database of the 'Institut d'Epidemiologie Neurologique et de Neurologie Tropicale' from inception to February 2013 for published original studies from SSA on neurodegenerative diseases and HIV-related neurocognitive impairment. Screening and data extraction were conducted by two investigators. Bibliographies and citations of eligible studies were investigated. RESULTS: In all 144 publications reporting on dementia (n=49 publications, mainly Alzheimer disease), Parkinsonism (PD, n=20), HIV-related neurocognitive impairment (n=47), Huntington disease (HD, n=19), amyotrophic lateral sclerosis (ALS, n=15), cerebellar degeneration (n=4) and Lewy body dementia (n=1). Of these studies, largely based on prevalent cases from retrospective data on urban populations, half originated from Nigeria and South Africa. The prevalence of dementia (Alzheimer disease) varied between <1% and 10.1% (0.7% and 5.6%) in population-based studies and from <1% to 47.8% in hospital-based studies. Incidence of dementia (Alzheimer disease) ranged from 8.7 to 21.8/1000/year (9.5 to 11.1), and major risk factors were advanced age and female sex. HIV-related neurocognitive impairment's prevalence (all from hospital-based studies) ranged from <1% to 80%. Population-based prevalence of PD and ALS varied from 10 to 235/100,000, and from 5 to 15/100,000 respectively while that for Huntington disease was 3.5/100,000. Equivalent figures for hospital based studies were the following: PD (0.41 to 7.2%), ALS (0.2 to 8.0/1000), and HD (0.2/100,000 to 46.0/100,000). CONCLUSIONS: The body of literature on neurodegenerative disorders in SSA is large with regard to dementia and HIV-related neurocognitive disorders but limited for other neurodegenerative disorders. Shortcomings include few population-based studies, heterogeneous diagnostic criteria and uneven representation of countries on the continent. There are important knowledge gaps that need urgent action, in order to prepare the sub-continent for the anticipated local surge in neurodegenerative diseases

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019

Background Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival. Methods We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (USMR). Scenarios for 2030 represent different potential trajectories, notably including potential effects of the COVID-19 pandemic and the potential impact of improvements preferentially targeting neonatal survival. Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index. Findings Global U5MR decreased from 71.2 deaths per 1000 livebirths (95% uncertainty interval WI] 68.3-74-0) in 2000 to 37.1 (33.2-41.7) in 2019 while global NMR correspondingly declined more slowly from 28.0 deaths per 1000 live births (26.8-29-5) in 2000 to 17.9 (16.3-19-8) in 2019. In 2019,136 (67%) of 204 countries had a USMR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030,154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. Deaths of children younger than 5 years totalled 9.65 million (95% UI 9.05-10.30) in 2000 and 5.05 million (4.27-6.02) in 2019, with the neonatal fraction of these deaths increasing from 39% (3.76 million 95% UI 3.53-4.021) in 2000 to 48% (2.42 million; 2.06-2.86) in 2019. NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0.80 (95% UI 0.71-0.86) deaths per 1000 livebirths and U5MR to 1.44 (95% UI 1-27-1.58) deaths per 1000 livebirths, and in 2019, there were as many as 1.87 million (95% UI 1-35-2.58; 37% 95% UI 32-43]) of 5.05 million more deaths of children younger than 5 years than the survival potential frontier. Interpretation Global child mortality declined by almost half between 2000 and 2019, but progress remains slower in neonates and 65 (32%) of 204 countries, mostly in sub-Saharan Africa and south Asia, are not on track to meet either SDG 3.2 target by 2030. Focused improvements in perinatal and newborn care, continued and expanded delivery of essential interventions such as vaccination and infection prevention, an enhanced focus on equity, continued focus on poverty reduction and education, and investment in strengthening health systems across the development spectrum have the potential to substantially improve USMR. Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed