TrafficNet: An Open Naturalistic Driving Scenario Library

The enormous efforts spent on collecting naturalistic driving data in the recent years has resulted in an expansion of publicly available traffic datasets, which has the potential to assist the development of the self-driving vehicles. However, we found that many of the attempts to utilize these datasets have failed in practice due to a lack of usability concern from the organizations that host these collected data. For example, extracting data associated with certain critical conditions from naturalistic driving data organized in chronological order may not be convenient for a vehicle engineer that doesn't have big data analytics experiences. To address the general usability challenges of these publicly available traffic datasets, we propose TrafficNet, a large-scale and extensible library of naturalistic driving scenarios, aiming at bridging the gap between research datasets and practically usable information for vehicle engineers and researchers. The proposed web-based driving scenario database preprocesses massive raw traffic data collected in chronological order into an organized scenario-based dataset by applying a set of categorization algorithms to label the naturalistic driving data with six different critical driving scenarios. TrafficNet opens not only the scenario library but also the source code of these categorization methods to the public, which will foster more sophisticated and accurate scenario-based categorization algorithms to advance the intelligent transportation research. The source code and the scenario database can be accessed at https://github.com/TrafficNet.Comment: IEEE 20th International Conference on Intelligent Transportatio

Towards Secure and Safe Appified Automated Vehicles

The advancement in Autonomous Vehicles (AVs) has created an enormous market for the development of self-driving functionalities,raising the question of how it will transform the traditional vehicle development process. One adventurous proposal is to open the AV platform to third-party developers, so that AV functionalities can be developed in a crowd-sourcing way, which could provide tangible benefits to both automakers and end users. Some pioneering companies in the automotive industry have made the move to open the platform so that developers are allowed to test their code on the road. Such openness, however, brings serious security and safety issues by allowing untrusted code to run on the vehicle. In this paper, we introduce the concept of an Appified AV platform that opens the development framework to third-party developers. To further address the safety challenges, we propose an enhanced appified AV design schema called AVGuard, which focuses primarily on mitigating the threats brought about by untrusted code, leveraging theory in the vehicle evaluation field, and conducting program analysis techniques in the cybersecurity area. Our study provides guidelines and suggested practice for the future design of open AV platforms

Sequence of the growth hormone (GH) gene from the silver carp (Hypophthalmichthys molitrix) and evolution of GH genes in vertebrates

The silver carp (Hypophthalmichthys molitrix) growth hormone (GH) genewas isolated and sequenced following amplification from genomic DNA by the polymerase chain reaction. The gene spans a region of approx. 2.5 kb nucleotides (nt) and consists of five exons. The sequence predicts a polypeptide of 210 amino acids (aa) including a putative signal peptide of 22 hydrophobic aa residues. The arrangement of exons and introns is identical to the GH genes of common carp, grass carp, and very similar to mammals and birds, but quite different from that for the GH genes of tilapia and salmonids. The silver carp GH gene shares a high homology at the nt and aa Ievels with those of grass carp (95.3% nt, 99.5% aa) and of common carp (81% nt, 95.7% aa)

Evaluation of electrohysterogram measured from different gestational weeks for recognizing preterm delivery:a preliminary study using random Forest

Developing a computational method for recognizing preterm delivery is important for timely diagnosis and treatment of preterm delivery. The main aim of this study was to evaluate electrohysterogram (EHG) signals recorded at different gestational weeks for recognizing the preterm delivery using random forest (RF). EHG signals from 300 pregnant women were divided into two groups depending on when the signals were recorded: i) preterm and term delivery with EHG recorded before the 26th week of gestation (denoted by PE and TE group), and ii) preterm and term delivery with EHG recorded during or after the 26th week of gestation (denoted by PL and TL group). 31 linear features and nonlinear features were derived from each EHG signal, and then compared comprehensively within PE and TE group, and PL and TL group. After employing the adaptive synthetic sampling approach and six-fold cross-validation, the accuracy (ACC), sensitivity, specificity and area under the curve (AUC) were applied to evaluate RF classification. For PL and TL group, RF achieved the ACC of 0.93, sensitivity of 0.89, specificity of 0.97, and AUC of 0.80. Similarly, their corresponding values were 0.92, 0.88, 0.96 and 0.88 for PE and TE group, indicating that RF could be used to recognize preterm delivery effectively with EHG signals recorded before the 26th week of gestation.</p

Tracing blastomere fate choices of early embryos in single cell culture

Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages. Tracing blastomere fate choices at the single cell level in vitro has not been possible because of the inability to isolate and cultivate early blastomeres as single cells. Here we report the establishment of single cell culture system in the fish medaka, enabling the isolation and cultivation of individual blastomeres from 16- to 64-cell embryos for fate tracing at the single cell level in vitro. Interestingly, these blastomeres immediately upon isolation exhibit motility, lose synchronous divisions and even stop dividing in &#x2265;50% cases, suggesting that the widely accepted nucleocytoplasmic ratio controlling synchronous divisions in entire embryos does not operate on individual blastomeres. We even observed abortive division, endomitosis and cell fusion. Strikingly, ~5% of blastomeres in single cell culture generated extraembryonic yolk syncytial cells, embryonic stem cells and neural crest-derived pigment cells with timings mimicking their appearance in embryos. We revealed the maternal inheritance of key lineage regulators and their differential expression in cleavage embryos. Therefore, medaka blastomeres possess the accessibility for single cell culture, previously unidentified heterogeneity in motility, division, gene expression and intrinsic ability to generate major extraembryonic and embryonic lineages without positioning cues. Our data demonstrate the fidelity and potential of the single cell culture system for tracking blastomere fate decisions under defined conditions in vitro