Security Issuance, Institutional Investors and Quid Pro Quo: Insights from SPACs

Security issuance is subject to informational and agency-related frictions. However, their effects on IPO underpricing are difficult to disentangle. We consider SPACs and use their institutional features to study these effects separately. To this end, we identify premium investors who produce information and whose participation is associated with higher SPAC success and announcement-period returns. In contrast, non-premium investors engage in quid pro quo, such that their high returns today means higher participation in weaker future deals. Furthermore, this quid pro quo is not pure agency cost: rather, it acts as insurance for issuers, enabling marginal firms to access financial markets

Low-complexity face-assisted video coding

[[abstract]]This paper presents a novel face-assisted video coding scheme to enhance the visual quality of the face regions in video telephony applications. A skin-color based face detection and tracking scheme is proposed to locate the face regions in real-time. After classifying the macroblocks into the face and non-face regions, we present a dynamic distortion weighting adjustment (DDWA) scheme to drop the static non-face macroblocks, and the saved bits are used to compensate the face region by adjusting the distortion weighting of the face macroblocks. The quality of face regions will thus be enhanced. Moreover, the computation originally required for the skipped macroblocks can also be saved. The experimental results show that the proposed method can significantly improve the PSNR and the subjective quality of face regions, while the degradation introduced on the non-face areas is relatively insensitive to human perception. The proposed algorithm is fully compatible with the H.263 standard, and the low complexity feature makes it well suited to implement for real-time applications[[fileno]]2030144030041[[department]]電機工程學

Nitroprusside modulates pulmonary vein arrhythmogenic activity

<p>Abstract</p> <p>Background</p> <p>Pulmonary veins (PVs) are the most important sources of ectopic beats with the initiation of paroxysmal atrial fibrillation, or the foci of ectopic atrial tachycardia and focal atrial fibrillation. Elimination of nitric oxide (NO) enhances cardiac triggered activity, and NO can decrease PV arrhythmogensis through mechano-electrical feedback. However, it is not clear whether NO may have direct electrophysiological effects on PV cardiomyocytes. This study is aimed to study the effects of nitroprusside (NO donor), on the ionic currents and arrhythmogenic activity of single cardiomyocytes from the PVs.</p> <p>Methods</p> <p>Single PV cardiomyocytes were isolated from the canine PVs. The action potential and ionic currents were investigated in isolated single canine PV cardiomyocytes before and after sodium nitroprusside (80 μM,) using the whole-cell patch clamp technique.</p> <p>Results</p> <p>Nitroprusside decreased PV cardiomyocytes spontaneous beating rates from 1.7 ± 0.3 Hz to 0.5 ± 0.4 Hz in 9 cells (P < 0.05); suppressed delayed afterdepolarization in 4 (80%) of 5 PV cardiomyocytes. Nitroprusside inhibited L-type calcium currents, transient outward currents and transient inward current, but increased delayed rectified potassium currents.</p> <p>Conclusion</p> <p>Nitroprusside regulates the electrical activity of PV cardiomyocytes, which suggests that NO may play a role in PV arrhythmogenesis.</p

Fuzzy Linguistic Optimization on Multi-Attribute Machining

Most existing multi-attribute optimization researches for the modern CNC (computer numerical control) turning industry were either accomplished within certain manufacturing circumstances, or achieved through numerous equipment operations. Therefore, a general deduction optimization scheme proposed is deemed to be necessary for the industry. In this paper, four parameters (cutting depth, feed rate, speed, tool nose runoff) with three levels (low, medium, high) are considered to optimize the multi-attribute (surface roughness, tool wear, and material removal rate) finish turning. Through FAHP (Fuzzy Analytic Hierarchy Process) with eighty intervals for each attribute, the weight of each attribute is evaluated from the paired comparison matrix constructed by the expert judgment. Additionally, twenty-seven fuzzy control rules using trapezoid membership function with respective to seventeen linguistic grades for each attribute are constructed. Considering thirty input and eighty output intervals, the defuzzifierion using center of gravity is thus completed. The TOPSIS (Technique for Order Preference by Similarity to Ideal Solution) is moreover utilized to integrate and evaluate the multiple machining attributes for the Taguchi experiment, and thus the optimum general deduction parameters can then be received. The confirmation experiment for optimum general deduction parameters is furthermore performed on an ECOCA-3807 CNC lathe. It is shown that the attributes from the fuzzy linguistic optimization parameters are all significantly advanced comparing to those from benchmark. This paper not only proposes a general deduction optimization scheme using orthogonal array, but also contributes the satisfactory fuzzy linguistic approach for multiple CNC turning attributes with profound insight

Realtime object extraction and tracking with an active camera using image mosaics

[[abstract]]Moving object extraction plays a key role in applications such as object-based videoconference, surveillance, and so on. The dimculties of moving object segmentation lie in the fact that physical objects are normally not homogeneous with to low-level features and it's usually tough to segment them accnrately and efficiently. Object segmentation based on prestored background information has proved to be effective and efficient in several applications such as videophone, video conferencing, and surveillance, etc. The previous works, however, were mainly concentrated on object segmentation with a static camera and in a stationary background. In this paper, we propose a robust and fast segmentation algorithm and a reliable tracking strategy without knowing the shape of the object in advance. The proposed system can real-time extract the foreground from the background and track the moving object with an active (pan-tilt) camera such that the moving object always stays around the center of images.[[fileno]]2030144030033[[department]]電機工程學

Evolutionary conservation of DNA-contact residues in DNA-binding domains

<p>Abstract</p> <p>Background</p> <p>DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DNA-binding proteins. In this study, we proposed a method to determine whether a domain or a protein can has DNA binding capability by considering evolutionary conservation of DNA-binding residues.</p> <p>Results</p> <p>Our method achieves high precision and recall for 66 families of DNA-binding domains, with a false positive rate less than 5% for 250 non-DNA-binding proteins. In addition, experimental results show that our method is able to identify the different DNA-binding behaviors of proteins in the same SCOP family based on the use of evolutionary conservation of DNA-contact residues.</p> <p>Conclusion</p> <p>This study shows the conservation of DNA-contact residues in DNA-binding domains. We conclude that the members in the same subfamily bind DNA specifically and the members in different subfamilies often recognize different DNA targets. Additionally, we observe the co-evolution of DNA-contact residues and interacting DNA base-pairs.</p

Managing cardiac arrest with refractory ventricular fibrillation in the emergency department: Conventional cardiopulmonary resuscitation versus extracorporeal cardiopulmonary resuscitation

AbstractAimRefractory ventricular fibrillation, resistant to conventional cardiopulmonary resuscitation (CPR), is a life threatening rhythm encountered in the emergency department. Although previous reports suggest the use of extracorporeal CPR can improve the clinical outcomes in patients with prolonged cardiac arrest, the effectiveness of this novel strategy for refractory ventricular fibrillation is not known. We aimed to compare the clinical outcomes of patients with refractory ventricular fibrillation managed with conventional CPR or extracorporeal CPR in our institution.MethodThis is a retrospective chart review study from an emergency department in a tertiary referral medical center. We identified 209 patients presenting with cardiac arrest due to ventricular fibrillation between September 2011 and September 2013. Of these, 60 patients were enrolled with ventricular fibrillation refractory to resuscitation for more than 10min. The clinical outcome of patients with ventricular fibrillation received either conventional CPR, including defibrillation, chest compression, and resuscitative medication (C-CPR, n=40) or CPR plus extracorporeal CPR (E-CPR, n=20) were compared.ResultsThe overall survival rate was 35%, and 18.3% of patients were discharged with good neurological function. The mean duration of CPR was longer in the E-CPR group than in the C-CPR group (69.90±49.6min vs 34.3±17.7min, p=0.0001). Patients receiving E-CPR had significantly higher rates of sustained return of spontaneous circulation (95.0% vs 47.5%, p=0.0009), and good neurological function at discharge (40.0% vs 7.5%, p=0.0067). The survival rate in the E-CPR group was higher (50% vs 27.5%, p=0.1512) at discharge and (50% vs 20%, p=0. 0998) at 1 year after discharge.ConclusionsThe management of refractory ventricular fibrillation in the emergency department remains challenging, as evidenced by an overall survival rate of 35% in this study. Patients with refractory ventricular fibrillation receiving E-CPR had a trend toward higher survival rates and significantly improved neurological outcomes than those receiving C-CPR

TRPC5 channels participate in pressure-sensing in aortic baroreceptors

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