The effects of short-term rainfall variability on leaf isotopic traits of desert plants in sand-binding ecosystems

Author's manuscript made available in accordance with the publisher's policy.Sand-binding vegetation is effective in stabilizing sand dunes and reducing soil erosion, thus helps minimize the detrimental effects of desertification. The aim of this study is to better understand the relationships between water and nutrient usage of sand-binding species, and the effects of succession and rainfall variability on plants’ water–nutrient interactions. We examined the effects of long-term succession (50 years), inter-annual rainfall variability (from 65% of the mean annual precipitation in 2004 to 42% in 2005) and seasonality on water–nutrient interactions of three major sand-binding species (Artemisia ordosica, Hedysarum scoparium and Caragana korshinskii) by measuring foliar δ13C, δ15N and [N]. Long-term succession in general did not significantly alter δ13C, δ15N and [N] of the three species. Short-term rainfall variability, however, significantly increased foliar δ13C levels of all three species by 1.0–1.8‰ during the severely dry year. No significant seasonal patterns were found in foliar δ13C and δ15N values of the three species, whereas foliar [N] varied by season. For the two leguminous shrubs, the correlations between δ13C and δ15N were positive in both sampling years, and the positive correlation between [N] and δ13C was only found in the severely dry year. The results indicate that these sand-binding plants have developed into a relatively stable stage and they are able to regulate their nitrogen and water use in responding to environmental conditions, which reinforces the effectiveness of plantation of native shrubs without irrigation in degraded areas. However, the results also indicate that short-term climate variability could have severe impact on the vegetation functions

Factors Influencing Chinese Male\u27s Willingness to Undergo Circumcision: A Cross-Sectional Study in Western China

Background Male circumcision (MC) has been shown to reduce the risk of female to male transmission of HIV. The goal of this survey was to explore the acceptability of MC among the Chinese and to identify factors associated with circumcision preference. Methods A cross-sectional survey was conducted between September 2009 and December 2010. We interviewed 2,219 male community participants, from three high HIV prevalence provinces in western China. A structured questionnaire was used to collect data on MC knowledge, willingness to accept MC, reasons to accept or refuse MC, and sexual behaviors and health. For those who refused MC, a health education intervention providing information on the benefits of circumcision was conducted. We used multiple logistic regression models to identify factors associated with the acceptability of MC. Results Of the respondents (n = 2,219), 44.6% (989/2,219) reported they would accept MC for the following reasons: promotion of female partners\u27 hygiene (60.3%), redundant foreskin (59.4%), prevention of penile cancer (50.2%), enhanced sexual pleasure (41.4%), and protection against HIV and STDs (34.2%). The multivariable logistic regression showed that five factors were associated with MC willingness: long foreskin (OR = 15.98), residing in Xinjiang province (OR = 3.69), being younger than 25 (OR = 1.60), knowing hazards of redundant foreskin (OR = 1.78), and having a friend who underwent circumcision (OR = 1.36). Conclusion The acceptability of male circumcision was high among the general population in China. Our study elucidates the factors associated with circumcision preference and suggests that more health education campaigns about positive health effects are necessary to increase the MC rate in China

Quick and efficient co-treatment of Zn2+/Ni2+ and CN- via the formation of Ni(CN)4 2- intercalated larger ZnAl-LDH crystals

The wide use of metal electroplating involving CN- necessitates the cost-effective treatment of both CN and metals (Zn, Cu, Ni etc.). In this research, we developed a novel strategy - Ni2+-assisted layered double hydroxide (LDH) precipitation - to simultaneously remove aqueous CN and Zn/Ni metals. The strategy is to convert CN-/Zn(CN)(4)(2-) to Ni(CN)(4)(2-) first, and then to quickly precipitate Ni(CN)(4)(2-)/CN- into LDH crystals. The conversion has been clearly evidenced by the change of CN characteristic FTIR bands of Zn-CN solution before and after adding Ni(NO3)(2). The intercalation and efficient removal of CN have also been confirmed through the formation of LDH crystals XRD and SEM. In particular, a set of optimized experimental factors has been obtained by investigating their effects on CN removal efficiency in the simulated tests. Remarkably, over 95% CN were removed with high removal efficiencies of metals. Our results thus suggest that the current strategy is a quick, efficient and promising way to simultaneously treat both Ni and metals/CN rich electroplating wastewaters. (C) 2014 Elsevier B.V. All rights reserved

Pharmacoeconomic evaluation of anti-obesity drugs for chronic weight management: a systematic review of literature

IntroductionPharmacological therapy is recommended as a second-line alternative to reverse obesity. Currently, five anti-obesity drugs (AODs) have been approved by the U.S. Food and Drug Administration (FDA) for chronic weight management. The aim of this paper is to investigate the pharmacoeconomic evaluation of AODs through a systematic review with a special focus on methodological considerations.MethodsWe searched the general and specific databases to identify the primary pharmacoeconomic evaluation of AODs.ResultsA total of 18 full-text articles and three conference abstracts were included in this review. Most of the economic assessments were still about Orlistat. And the observations we could make were consistent with the previous systematic review. A few studies were on the combined therapies (i.e. PHEN/TPM ER and NB ER) compared to different comparators, which could hardly lead to a generalized summary of the cost-effectiveness. Most recently, pharmacoeconomic evidence on the newest GLP 1 RA approved for the indication of obesity or obesity with at least one comorbidity emerged gradually. Modelling-based cost-utility analysis is the major type of assessment method. In the modelling studies, a manageable number of the key health states and the state transitions were structured to capture the disease progression. In particular, the principal structure of the decision model adopted in the three studies on the newly approved drug was nearly the same, which enables more in-depth comparisons and generalizations of the findings.ConclusionThis study provided an up-to-date overview of the strengths and areas for improvement in the methodological design of the pharmacoeconomic evaluation of the licensed drugs for chronic weight management. Future modelling evaluations would benefit from a better understanding of the long-term weight loss effects of the current therapeutic options and the weight rebound process after the discontinuation of treatment.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022302648, identifier CRD42022302648

Factors Influencing Chinese Male's Willingness to Undergo Circumcision: A Cross-Sectional Study in Western China

BACKGROUND: Male circumcision (MC) has been shown to reduce the risk of female to male transmission of HIV. The goal of this survey was to explore the acceptability of MC among the Chinese and to identify factors associated with circumcision preference. METHODS: A cross-sectional survey was conducted between September 2009 and December 2010. We interviewed 2,219 male community participants, from three high HIV prevalence provinces in western China. A structured questionnaire was used to collect data on MC knowledge, willingness to accept MC, reasons to accept or refuse MC, and sexual behaviors and health. For those who refused MC, a health education intervention providing information on the benefits of circumcision was conducted. We used multiple logistic regression models to identify factors associated with the acceptability of MC. RESULTS: Of the respondents (n = 2,219), 44.6% (989/2,219) reported they would accept MC for the following reasons: promotion of female partners' hygiene (60.3%), redundant foreskin (59.4%), prevention of penile cancer (50.2%), enhanced sexual pleasure (41.4%), and protection against HIV and STDs (34.2%). The multivariable logistic regression showed that five factors were associated with MC willingness: long foreskin (OR = 15.98), residing in Xinjiang province (OR = 3.69), being younger than 25 (OR = 1.60), knowing hazards of redundant foreskin (OR = 1.78), and having a friend who underwent circumcision (OR = 1.36). CONCLUSION: The acceptability of male circumcision was high among the general population in China. Our study elucidates the factors associated with circumcision preference and suggests that more health education campaigns about positive health effects are necessary to increase the MC rate in China

Periodic dynamics of a single species model with seasonal Michaelis-Menten type harvesting

In this paper, we formulate a seasonally interactive model between closed seasons and open seasons with Michaelis-Menten type harvesting based on some management and capture methods of renewable resources. It is assumed that the population growth obeys the logistic equation in closed seasons and is captured following Michaelis-Menten type response function in open seasons. We define a length threshold of the closed season T¯⁎, which depends on the harvesting parameter. Under the extinct condition of the corresponding continuous harvesting model, by setting the closed season, theoretical results show that the origin is globally asymptotically stable if and only if T¯≤T¯⁎, and there exists a unique globally asymptotically stable T-periodic solution if and only if T¯>T¯⁎. In particular, under the critical conditions on special harvest parameters, it is found that the T-periodic solution still exists as long as an arbitrary positive close season is formulated. Numerical examples are carried out to confirm the obtained theoretical results. Brief conclusions and discussions on our findings are also provided

Ranking of CMIP5 GCM Skills in Simulating Observed Precipitation over the Lower Mekong Basin, Using an Improved Score-Based Method

This study assessed the performances of 34 Coupled Model Intercomparison Project Phase 5 (CMIP5) general circulation models (GCMs) in reproducing observed precipitation over the Lower Mekong Basin (LMB). Observations from gauge-based data of the Asian Precipitation-Highly Resolved Observational Data Integration Towards Evaluation of Water Resources (APHRODITE) precipitation data were obtained from 1975 to 2004. An improved score-based method was used to rank the performance of the GCMs in reproducing the observed precipitation over the LMB. The results revealed that most GCMs effectively reproduced precipitation patterns for the mean annual cycle, but they generally overestimated the observed precipitation. The GCMs showed good ability in reproducing the time series characteristics of precipitation for the annual period compared to those for the wet and dry seasons. Meanwhile, the GCMs obviously reproduced the spatial characteristics of precipitation for the dry season better than those for annual time and the wet season. More than 50% of the GCMs failed to reproduce the positive trend of the observed precipitation for the wet season and the dry season (approximately 52.9% and 64.7%, respectively), and approximately 44.1% of the GCMs failed to reproduce positive trend for annual time over the LMB. Furthermore, it was also revealed that there existed different robust criteria for assessing the GCMs’ performances at a seasonal scale, and using multiple criteria was superior to a single criterion in assessing the GCMs’ performances. Overall, the better-performed GCMs were obtained, which can provide useful information for future precipitation projection and policy-making over the LMB

Assessing the Performance of CMIP5 GCMs for Projection of Future Temperature Change over the Lower Mekong Basin

In this study, we assessed the performance of 34 Coupled Model Intercomparison Project Phase 5 (CMIP5) general climate models (GCMs) for simulating the observed temperature over the Lower Mekong Basin (LMB) in 1961⁻2004. An improved score-based method was used to rank the performance of the GCMs over the LMB. Two methods of multi-model ensemble (MME), sub-ensemble from the top 25% ranked GCMs and full ensemble from the entire GCMs, were calculated using arithmetic mean (AM) method and downscaled using the Delta method to project future temperature change during two future time periods, the near future (2006⁻2049) and the far future (2050⁻2093), under representative concentration pathways (RCP2.6, RCP4.5, and RCP8.5 scenarios) over the LMB. The improved score-based method combining multiple criteria showed a robust assessment of the GCMs performance over the LMB, which can provide good information for projecting future temperature change. The results showed a significant increase in temperature over the LMB under the two ensembles. However, there were differences in the magnitudes of the future temperature increase between the two ensemble methods, with a higher mean annual temperature increase from full ensemble and sub-ensemble at 1.26 °C (1.09 °C), 1.90 °C (1.70 °C), and 2.97 °C (2.78 °C) during 2050⁻2093 under the RCP2.6, RCP4.5, and RCP8.5 scenarios compared to the values at 0.93 °C (0.87 °C), 0.99 °C (0.95 °C), and 1.09 °C (1.06 °C) during 2006⁻2049, respectively, relative to the reference time period of 1961⁻2004. In the future (2006⁻2093), the temperature is likely to increase at 0.06 °C, 0.18 °C, and 0.39 °C decade−1 under the RCP2.6, RCP4.5, and RCP8.5 scenarios by the sub-ensemble, while a higher temperature increase at 0.08 °C, 0.20 °C, and 0.42 °C was found by the full ensemble over the LMB, relative to the reference time period of 1961⁻2004. On the whole, the higher warming mainly occurred in the northern and central areas over the LMB, while the lower warming mainly occurred in the southeast and the southwest, especially under the RCP4.5 and RCP8.5 scenarios, with the warming increased with increasing RCP for both ensembles. Moreover, in order to reduce the uncertainty of temperature projection in further studies in the LMB, multiple methods of GCMs ensemble should be considered and compared

Temporal and Spatial Variations of Precipitation δ18O and Controlling Factors on the Pearl River Basin and Adjacent Regions

Based on the precipitation  δ18O values from the datasets of the Global Network of Isotopes in Precipitation (GNIP), the National Centers for Environmental Prediction/National Center for Atmospheric Research (NCEP/NCAR) Reanalysis data, and previous researches, we explored the temporal and spatial variations of precipitation  δ18O in a typical monsoon climate zone, the Pearl River basin (PRB), and adjacent regions. The results showed that the temporal variations of precipitation  δ18O for stations should be correlated with water vapor sources, the distance of water vapor transport, the changes in location, and intensity of the intertropical convergence zone (ITCZ) rather than “amount effect.” Meanwhile, local meteorological and geographical factors showed close correlations with mean weighted precipitation  δ18O values, suggesting that “altitude effect” and local meteorological conditions were significant for the spatial variations of precipitation  δ18O. Moreover, we established linear regression models for estimating the mean weighted precipitation  δ18O values, which could better estimate variations in precipitation  δ18O than the Bowen and Wilkinson model in the PRB and adjacent regions